Sepsis Clinical Management Quiz
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Questions and Answers

What is the primary effect of an excessive immune response in sepsis?

  • Increased blood flow to organs
  • Reduced white blood cell count
  • Increased capillary permeability (correct)
  • Enhanced local immune activity
  • What is the primary goal for maintaining SpO₂ levels in clinical management?

  • Enhance oxygen delivery to tissues (correct)
  • Minimize blood pressure
  • Prevent respiratory distress
  • Reduce heart rate
  • What occurs when the body experiences reduced blood flow to organs during sepsis?

  • Increased aerobic respiration
  • Improved tissue perfusion
  • Metabolic acidosis due to lactic acid buildup (correct)
  • Enhanced clot formation
  • Which of the following is a broad-spectrum antibiotic mentioned in clinical management?

    <p>Ceftriaxone</p> Signup and view all the answers

    What initiates the formation of micro clots in the context of sepsis?

    <p>Extrinsic clotting cascade activation</p> Signup and view all the answers

    How does the body respond to hypotension during sepsis?

    <p>By releasing adrenaline</p> Signup and view all the answers

    What is the role of the ODP in recognizing sepsis?

    <p>Perform an A-E assessment</p> Signup and view all the answers

    What is the fluid challenge volume and rate mentioned for establishing fluid therapy?

    <p>500 ml of Saline over ≤15 min</p> Signup and view all the answers

    What leads to multiple organ failure in sepsis?

    <p>Switching to anaerobic respiration</p> Signup and view all the answers

    What is the significance of measuring lactate levels in clinical management?

    <p>To evaluate the degree of acidosis</p> Signup and view all the answers

    What respiratory rate indicates a potential red flag for sepsis or shock?

    <p>25/min</p> Signup and view all the answers

    Which of the following is a component of the Sepsis 6 protocol?

    <p>IV fluids for fluid loss replacement</p> Signup and view all the answers

    What is the minimum urine output aimed for to ensure kidney perfusion in a patient?

    <p>0.5 mLs/kg/hour</p> Signup and view all the answers

    Which factor is NOT one of the three main components needed for effective blood flow?

    <p>Effective Nervous System</p> Signup and view all the answers

    What does a decreased systolic BP of 40 mm Hg less than baseline indicate?

    <p>Possible shock or sepsis</p> Signup and view all the answers

    What is a key characteristic of sepsis?

    <p>It results from the body's response to an infection.</p> Signup and view all the answers

    Which symptom is NOT typically associated with sepsis?

    <p>High blood pressure</p> Signup and view all the answers

    In the A-E assessment, which finding is indicative of respiratory distress in sepsis?

    <p>Tachyapnea with low SpO2</p> Signup and view all the answers

    Which medication is recommended to increase vascular resistance in septic shock?

    <p>Norepinephrine</p> Signup and view all the answers

    What population is at a higher risk for experiencing shock?

    <p>Patients with cardiovascular issues</p> Signup and view all the answers

    What is the effect of adrenaline on the heart regarding its rate and contraction force?

    <p>Increases heart rate and increases force of contraction</p> Signup and view all the answers

    What happens to the arteries when adrenaline binds to alpha-1 receptors?

    <p>They constrict, reducing blood flow</p> Signup and view all the answers

    In the provided blood gas analysis, which test value indicates acidosis?

    <p>pH of 7.23</p> Signup and view all the answers

    What might be inferred from a low PaCO2 value of 3.2 kPa in the blood gas analysis?

    <p>Patient is likely hyperventilating</p> Signup and view all the answers

    What is the metabolic problem indicated by a low HCO3 value of 12.6 mmol/l?

    <p>Metabolic acidosis</p> Signup and view all the answers

    What is the primary purpose of administering oxygen in this scenario?

    <p>To maintain SpO2 above 94%</p> Signup and view all the answers

    Why should Compound Sodium Lactate (Hartmann's) not be administered?

    <p>It contains lactate, which is already high due to metabolic acidosis</p> Signup and view all the answers

    What should be done first when initiating antibiotic therapy?

    <p>Give broad spectrum IV antibiotics</p> Signup and view all the answers

    What role does Noradrenaline play in this treatment plan?

    <p>It increases the tone of the vessels by acting on α1 receptors</p> Signup and view all the answers

    Why is measuring urine output important during sepsis management?

    <p>To monitor renal function, which is often limited</p> Signup and view all the answers

    What is the main cause of sepsis symptoms in the body?

    <p>Immunological overactivity due to excess leukocytes</p> Signup and view all the answers

    Which of the following is a physiological effect of sepsis?

    <p>Decreased urine output</p> Signup and view all the answers

    Which treatment should be administered within the first hour of recognizing sepsis?

    <p>Broad spectrum antibiotics</p> Signup and view all the answers

    What causes the increased heart rate commonly observed in sepsis?

    <p>Adrenaline release causing vascular dilation</p> Signup and view all the answers

    Which condition is indicated by decreased capillary refill time in a patient with sepsis?

    <p>Decreased perfusion to tissues</p> Signup and view all the answers

    What change in metabolic activity occurs as a response to sepsis?

    <p>Increased anaerobic metabolism</p> Signup and view all the answers

    What is a sign of multi-organ failure in sepsis?

    <p>Decreased urine output</p> Signup and view all the answers

    Which symptom may indicate a seriously progressed case of sepsis?

    <p>Cyanosis of lips and tongue</p> Signup and view all the answers

    Study Notes

    Clinical Management

    • Give Oxygen. Try to maintain SpO2 ≥94%.
    • Take blood cultures.
    • Give broad spectrum IV antibiotics.
    • Establish a fluid challenge (500 ml of Saline), over ≤15 min.
    • Measure the lactate, how much acidotic?
    • Monitor the urine output.

    Antibiotic Crystalloids

    • Cefotaxime 500 ml of Saline

    Role of the ODP

    • The role of the ODP is to recognise the sepsis, to perform an A-E assessment, to raise concerns, to support the anaesthetist, work appropriately within a multi-disciplinary team.

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    Description

    Test your knowledge on the clinical management of sepsis. This quiz covers key concepts such as immune response, fluid therapy, and the importance of monitoring vital signs and lab values in septic patients. Dive into the critical aspects needed for effective intervention in sepsis.

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