Podcast
Questions and Answers
What do first order neurons conduct?
What do first order neurons conduct?
What do second order neurons carry information to?
What do second order neurons carry information to?
Thalamus
What do third order neurons carry sensory information to?
What do third order neurons carry sensory information to?
Cerebral cortex
Referred pain is perceived as occurring on the skin surface.
Referred pain is perceived as occurring on the skin surface.
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What are simple mechanoreceptors?
What are simple mechanoreceptors?
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What are complex mechanoreceptors?
What are complex mechanoreceptors?
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A detectable change in the internal or external environment is known as a ______.
A detectable change in the internal or external environment is known as a ______.
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What is an adequate stimulus?
What is an adequate stimulus?
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What is receptor potential?
What is receptor potential?
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What does labeled line coding refer to?
What does labeled line coding refer to?
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Match the mechanoreceptors with their functions:
Match the mechanoreceptors with their functions:
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What is the function of free nerve endings in the skin?
What is the function of free nerve endings in the skin?
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How do we encode the length of the stimulus in a first order sensory neuron?
How do we encode the length of the stimulus in a first order sensory neuron?
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How is intensity encoded?
How is intensity encoded?
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Tonic receptors adapt quickly to stimuli.
Tonic receptors adapt quickly to stimuli.
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Phasic receptors adapt slowly to stimuli.
Phasic receptors adapt slowly to stimuli.
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How do overlap and convergence of receptor fields influence sensory sensitivity?
How do overlap and convergence of receptor fields influence sensory sensitivity?
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What is the function of sensory fiber type Aalpha (I)?
What is the function of sensory fiber type Aalpha (I)?
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What is the function of sensory fiber Abeta (II)?
What is the function of sensory fiber Abeta (II)?
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What is the function of Adelta fiber (III)?
What is the function of Adelta fiber (III)?
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What is the function of C (type IV) fiber?
What is the function of C (type IV) fiber?
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Differentiate between dermatome and receptive field:
Differentiate between dermatome and receptive field:
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What is lateral inhibition?
What is lateral inhibition?
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Map the dorsal column-medial lemniscal pathway.
Map the dorsal column-medial lemniscal pathway.
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Map the spinothalamic pathway.
Map the spinothalamic pathway.
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Map the pathway that conveys fine touch sensation from the head/face.
Map the pathway that conveys fine touch sensation from the head/face.
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Where are the cell bodies of the first order sensory neurons of the face?
Where are the cell bodies of the first order sensory neurons of the face?
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Explain the topographic organization of sensory transmission from the spinal cord to sensory cortex.
Explain the topographic organization of sensory transmission from the spinal cord to sensory cortex.
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Map the pathway for pain and temperature of the face.
Map the pathway for pain and temperature of the face.
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Study Notes
Neuron Types in Sensory Systems
- First-order neurons carry impulses from skin receptors and proprioceptors to the spinal cord or brain stem, synapsing with second-order neurons.
- Second-order neurons transmit information from the central nervous system to the thalamus and decussate, crossing to the opposite side of the CNS.
- Third-order neurons relay sensory information from the thalamus to the cerebral cortex.
Pain Perception and Mechanisms
- Referred pain occurs when visceral pain is felt on the skin, as visceral organs share sensory afferents with specific dermatomes (e.g., heart attack may cause shoulder and arm pain).
- Lateral inhibition enhances contrast in sensory input through GABA activity by second-order neurons.
Mechanoreceptors
- Simple mechanoreceptors include free nerve endings for pain and temperature, as well as hair follicles detecting mechanical stimuli.
- Complex mechanoreceptors are specialized nerve endings encapsulated for more refined sensitivity, such as Meissner's corpuscles for light touch and Pacinian corpuscles for vibration.
Signal Processing and Encoding
- Stimulus energy refers to detectable environmental changes processed into electrical signals via stimulus transduction.
- Adequate stimulus is the form of energy to which a receptor is most responsive.
- Receptor potential indicates the graded potential change in sensory receptor membranes.
- Labeled line coding ensures a 1:1 association between receptors and sensations, maintaining specific sensory perceptions.
Skin Mechanoreceptors
- Meissner's corpuscle detects fine touch.
- Merkel's disks respond to pressure and texture.
- Ruffini endings sense skin stretch, part of proprioception.
- Pacinian corpuscles detect vibrations, often located in joints.
- Free nerve endings encompass nociceptors (pain), thermoreceptors (temperature), and those in hair follicles.
Receptor Adaptation
- Tonic receptors are slow to adapt (e.g., persistent pain or temperature sensation).
- Phasic receptors adapt quickly, becoming less responsive after initial stimulation (e.g., feeling the texture of clothing).
Sensory Fibers
- Aalpha fibers (I): Large diameter, myelinated; responsible for proprioception.
- Abeta fibers (II): Large diameter, myelinated; convey fine touch sensations.
- Adelta fibers (III): Small diameter, lightly myelinated; transmit fast pain and temperature signals.
- C fibers (IV): Small diameter, unmyelinated; associated with slow pain.
Sensory Field Concepts
- Dermatome represents skin regions related to a specific dorsal root ganglion (DRG).
- Receptive field refers to the area influenced by one sensory neuron.
Sensory Pathways
- Dorsal column-medial lemniscal pathway: First-order neurons ascend ipsilaterally, synapsing in the cuneate/gracilis nucleus; second-order neurons cross midline and ascend to thalamus; third-order neurons project to the primary sensory cortex.
- Spinothalamic pathway: First-order neurons synapse in the dorsal horn upon entering the CNS; second-order neurons decussate and ascend to thalamus; third-order neurons transmit to sensory cortex.
- Pathway for fine touch from head/face: First-order neurons from the trigeminal ganglion synapse in the ipsilateral chief trigeminal nucleus; second-order neurons cross over ascending to VPM of thalamus; third-order neurons project to the sensory cortex.
- Pain and temperature pathway for face: First-order neurons descend into the ipsilateral spinal trigeminal nucleus; second-order neurons cross and ascend contralaterally to the VPM of thalamus; third-order neurons relay to sensory cortex.
Cellular Structures
- First-order sensory neuron cell bodies for the face are located in the trigeminal ganglion, unlike the DRG for other body parts.
Topographic Organization
- Sensory information follows a structured pathway from the spinal cord through multiple relay points to the sensory cortex, maintaining regional organization throughout the process.
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Test your knowledge on the sensory systems with these flashcards. Learn the definitions and functions of first order and second order neurons as they relate to the nervous system. Perfect for students studying neuroscience or biology.