Sensory Physiology: Somatosensation Overview
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Questions and Answers

What type of sensation does the lateral spinothalamic tract primarily convey?

  • Fine touch and vibration sensations
  • Pain and temperature sensations (correct)
  • Touch and pressure sensations
  • Tickle and itch sensations
  • Which pathway is responsible for relaying information related to conscious proprioception?

  • Anterior spinothalamic tract
  • Posterior column medial lemniscus (correct)
  • Lateral spinothalamic tract
  • Spinocerebellar tracts
  • Where do the axons of the second order neurons originating from the gracile nucleus synapse?

  • Primary sensory cortex
  • Medulla oblongata
  • Spinal cord
  • Thalamus (correct)
  • What distinguishes the spinocerebellar tracts from the other sensory pathways mentioned?

    <p>They are ipsilateral. (C)</p> Signup and view all the answers

    Which structure is NOT primarily involved in the relay of tactile sensations?

    <p>Lateral spinothalamic tract (C)</p> Signup and view all the answers

    What type of neurons synapse in the primary somatosensory area of the cerebral cortex?

    <p>Third order neurons (A)</p> Signup and view all the answers

    Which component of muscle spindles is primarily responsible for sending information to the nervous system?

    <p>Afferent fibers (B)</p> Signup and view all the answers

    What function do gamma (γ) motor neurons serve in relation to muscle spindles?

    <p>Control intrafusal muscle fibers (B)</p> Signup and view all the answers

    What type of sensory receptor is responsible for detecting changes in body position, muscle length, and tension?

    <p>Proprioceptors (D)</p> Signup and view all the answers

    How is a receptor potential generated?

    <p>By the deformation of the plasma membrane of sensory neurons (C)</p> Signup and view all the answers

    Which classification of sensory receptors specializes in detecting light?

    <p>Photoreceptors (B)</p> Signup and view all the answers

    What distinguishes phasic receptors from tonic receptors?

    <p>Phasic receptors adapt quickly to constant stimuli, while tonic receptors do not. (C)</p> Signup and view all the answers

    Which of the following best describes the sensory pathway from receptors to the sensory cortex?

    <p>1st order neurone, 2nd order neurone, thalamus, 3rd order neurone (D)</p> Signup and view all the answers

    What term describes the area in which stimulation leads to the response of a particular sensory neuron?

    <p>Receptive field (A)</p> Signup and view all the answers

    What is the primary role of encapsulated nerve endings?

    <p>To provide fine touch and pressure information (C)</p> Signup and view all the answers

    Which pathway is primarily responsible for relaying pain and thermal sensations?

    <p>Spinothalamic pathway (C)</p> Signup and view all the answers

    In terms of sensory acuity, what does 'two-point discrimination' depend on?

    <p>The overlapping of receptive fields and their density (A)</p> Signup and view all the answers

    What is a key characteristic of free nerve endings?

    <p>They are bare dendrites and detect pain. (A)</p> Signup and view all the answers

    Flashcards

    Lateral Spinothalamic Tract (STT)

    The pathway that transmits information about pain and temperature, originating in the spinal cord and ascending to the thalamus.

    Anterior Spinothalamic Tract (STT)

    The pathway that transmits information about tickle, itch, and crude touch, originating in the spinal cord and ascending to the thalamus.

    Posterior Column-Medial Lemniscus Pathway (PCML)

    The pathway that transmits information about conscious proprioception (body position and movement) and fine touch, pressure, and vibration, originating in the spinal cord and ascending to the thalamus.

    Muscle Spindle

    A specialized sensory receptor within muscles that detects changes in muscle length and tension, helping to sense body position and movement.

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    First Order Neuron

    The first neuron in the sensory pathway that transmits information from the periphery (e.g., skin, muscle) to the spinal cord.

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    Second Order Neuron

    The second neuron in the sensory pathway that transmits information from the spinal cord to the thalamus.

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    Third Order Neuron

    The third neuron in the sensory pathway that transmits information from the thalamus to the cerebral cortex (specifically the primary somatosensory area).

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    Spinocerebellar Tract

    The pathway that transmits information from proprioceptors on one side of the body to the same side of the cerebellum.

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    1st order neurons

    These are the nerve cells that carry sensory information from the periphery to the spinal cord or brainstem.

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    2nd order neurons

    These neurons relay sensory information from the spinal cord or brainstem to the thalamus in the brain.

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    3rd order neurons

    These are the final neurons in the sensory pathway that transmit information from the thalamus to the sensory cortex of the brain.

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    Graded potential

    A change in the membrane potential of a sensory receptor, proportional to the intensity of the stimulus. It may or may not trigger an action potential.

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    Receptor potential

    A type of graded potential specifically generated in sensory receptor cells. It triggers the release of neurotransmitters, which in turn generate postsynaptic potentials in the first-order neuron.

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    Mechanoreceptors

    Sensory receptors that respond to mechanical stimuli like pressure, touch, and vibration.

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    Thermoreceptors

    Sensory receptors that detect changes in temperature.

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    Nociceptors

    Sensory receptors that detect pain.

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    Pacinian corpuscle

    A specialized mechanoreceptor located in the skin that detects deep pressure and vibrations.

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    Receptive field

    This is the area of the body that, when stimulated, activates a particular sensory neuron. The size and density of receptive fields influence our ability to discriminate between stimuli.

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    Study Notes

    Somatosensation: Sensory Information Transmission

    • Information from the periphery to higher centers is relayed by first, second, and third-order neurons.

    Graded Potentials

    • Sensory transduction involves a change in membrane potential, proportional to the stimulus.
    • Three types of sensory receptors: free nerve endings, encapsulated nerve endings, and separate cells.

    Receptor Potentials

    • Separate cells (e.g., hair cells, taste buds) generate receptor potentials.
    • Stimulation triggers neurotransmitter release, leading to postsynaptic potentials in first-order neurons.
    • Sufficiently large receptor potentials initiate action potentials (APs).

    Graded Potentials (Free and Encapsulated Receptors)

    • Free and encapsulated nerve endings generate graded potentials.
    • These potentials trigger APs if the threshold is reached.

    Receptor Types: Classification

    • Structure: Free nerve endings, encapsulated endings, separate cells.
    • Location: Exteroreceptors (external environment), interoreceptors (internal environment), proprioceptors (body position, muscle).
    • Stimulus Type: Mechanoreceptors, chemoreceptors, thermoreceptors, osmoreceptors, nociceptors, photoreceptors.

    Pacinian Corpuscle

    • Contains lamellae that deform when pressure is applied.
    • Deformation opens sodium channels, leading to membrane depolarization (mechanosensitive).

    Adaptation in Sensory Receptors

    • Phasic receptors: Rapidly adapt, signaling changes in stimulus.
    • Slow-adapting receptors: Continuously signal stimulus even with sustained stimulation.

    Receptive Field

    • Area of stimulation that causes a response in a sensory neuron.
    • Receptive field size/overlap affect sensory acuity.

    Sensory Acuity ("Two-point Discrimination")

    • Smaller receptive fields and higher neuron density result in better discrimination.
    • Overlapping receptive fields reduce discrimination.

    Sensation vs. Perception

    • Sensation refers to the raw sensory input.
    • Perception involves higher-level processing for interpretation and understanding.

    Dorsal Root

    • Part of the somatic sensory pathway.

    Somatic Sensory Pathways

    • Three-neuron pathway: first-order (receptor to spinal cord/brainstem), second-order (spinal cord/brainstem to thalamus), third-order (thalamus to sensory cortex).

    Spinothalamic Pathways

    • Relays pain, temperature, tickle, itch, and crude touch.
    • First-order neurons synapse with second-order neurons that immediately cross to the opposite side of the spinal cord.
    • The second-order neuron ascends in the lateral or anterior spinothalamic tract to the thalamus.
    • Third-order neurons project to the primary somatosensory area of the cerebral cortex.

    Posterior Column-Medial Lemniscus Pathway

    • Relays conscious proprioception, fine touch, pressure, and vibration.
    • First-order axons ascend in the dorsal columns (gracile and cuneate tracts).
    • Second-order neurons synapse in the medulla (gracile and cuneate nuclei), cross over, and ascend in the medial lemniscus.
    • Third-order neurons project to the primary sensory cortex.

    Proprioception

    • Sensory information from muscle spindles (intrafusal fibers) travels along axons to the spinal cord.
    • Axons ascend in the dorsal columns (gracile/cuneate tracts).
    • Second-order neurons synapse in the medulla (gracile/cuneate nuclei).
    • Third-order neurons project to the primary sensory area.

    Spinocerebellar Tracts

    • Convey proprioceptive information to the cerebellum (ipsilateral).
    • Two tracts: anterior and posterior.
    • This information is not consciously perceived.

    Muscle Spindles

    • Intrafusal fibers (nuclear bag & chain) are specialized sensory receptors in muscles.
    • Afferents (1a and group II) provide information about muscle length and changes.
    • Efferents (γ-motor neurons) control intrafusal fibers' sensitivity.
    • α-motor neurons control extrafusal fibers.

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    Description

    Explore the complex mechanisms of somatosensation, focusing on sensory information transmission and graded potentials. This quiz delves into the roles of various sensory receptors and how they transmit information to the nervous system, making it essential for understanding sensory physiology.

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