6 Questions
What is the difference in STT values between kittens and adult cats?
Kittens have higher STT values
What is the effect of age on STT in adult cats?
Age is not a significant factor in determining STT
What is the reported range of mean TBUT for normal healthy dogs?
14.7– 28.9 seconds
Why did the authors of the study use diluted fluorescein sodium?
The reason is not specified in the study
What did the study find about the TBUT values of brachycephalic breeds compared to non-brachycephalic breeds?
The TBUT values were 18% more accelerated in brachycephalic breeds
What is the range of mean TBUT values reported in the literature for normal healthy dogs?
5.9-8.6 seconds
Study Notes
Tear Film Instability in Dogs
- Unstable tear film (TF) was found in brachycephalic dogs compared to non-brachycephalic dogs.
- The TBUT (tear break-up time) of brachycephalic breeds was 18% more accelerated than non-brachycephalic breeds.
Normal TBUT Values
- Mean normal TBUT for adult healthy dogs: 14.7–28.9 seconds.
- Mean TBUT of both brachycephalic and non-brachycephalic breeds in the present study was at least 50% more accelerated than normal reference values.
Factors Affecting TBUT
- Environment: hot and dry weather may affect TBUT in dogs.
- Fluorescein volume and/or concentration may affect TBUT.
- Poor reliability of TBUT may be a factor.
- Season and environmental factors (temperature, humidity, and altitude) may affect TBUT in dogs.
Comparative Studies
- A recent study reported no difference in mean TBUT between different methods of fluorescein sodium application.
- Mean TBUT values for normal dogs: 5.9–8.6 seconds, similar to the present study.
TBUT-Affecting Factors in Other Animals
- Topical anesthetics, such as tetracaine, decrease TBUT in horses.
- In cats, TBUT is shorter with feline herpesvirus 1 (FHV-1) infection, ulcerative keratitis, conjunctivitis, and corneal sequestrum.
- Anesthesia reduces TBUT in cats.
Tear Film Instability in Dogs
- Unstable tear film (TF) was found in brachycephalic dogs compared to non-brachycephalic dogs.
- The TBUT (tear break-up time) of brachycephalic breeds was 18% more accelerated than non-brachycephalic breeds.
Normal TBUT Values
- Mean normal TBUT for adult healthy dogs: 14.7–28.9 seconds.
- Mean TBUT of both brachycephalic and non-brachycephalic breeds in the present study was at least 50% more accelerated than normal reference values.
Factors Affecting TBUT
- Environment: hot and dry weather may affect TBUT in dogs.
- Fluorescein volume and/or concentration may affect TBUT.
- Poor reliability of TBUT may be a factor.
- Season and environmental factors (temperature, humidity, and altitude) may affect TBUT in dogs.
Comparative Studies
- A recent study reported no difference in mean TBUT between different methods of fluorescein sodium application.
- Mean TBUT values for normal dogs: 5.9–8.6 seconds, similar to the present study.
TBUT-Affecting Factors in Other Animals
- Topical anesthetics, such as tetracaine, decrease TBUT in horses.
- In cats, TBUT is shorter with feline herpesvirus 1 (FHV-1) infection, ulcerative keratitis, conjunctivitis, and corneal sequestrum.
- Anesthesia reduces TBUT in cats.
The Schirmer Tear Test is a conventional method for evaluating the aqueous portion of tear film. It's a widely used diagnostic tool in ophthalmology. This quiz will assess your knowledge of the STT.
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