SARS Quiz

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Questions and Answers

What is the main reservoir for SARS-COV-1?

  • Dogs
  • Cats
  • Bats (correct)
  • Pigs

What is the transmission mode of SARS?

  • Sexual transmission
  • Vector-borne
  • Contact with bodily fluids
  • Droplet aerosol and fomite deposited on the respiratory mucosal epithelium (correct)

What is the fatality rate of SARS?

  • 20%
  • 1%
  • 5%
  • 10% (correct)

What is the pathogenesis of SARS?

<p>High viral load in the lower respiratory tract (D)</p> Signup and view all the answers

What is the recommended therapy for SARS?

<p>Antiviral drugs (D)</p> Signup and view all the answers

What is the most common disease caused by Mycobacterial infections?

<p>Tuberculosis (B)</p> Signup and view all the answers

What is the leading cause of death among infectious diseases worldwide?

<p>Tuberculosis (D)</p> Signup and view all the answers

What is the most effective way to eliminate reservoirs of tuberculosis?

<p>Early detection of cases and prompt treatment (A)</p> Signup and view all the answers

What is the possible cause of the increase in tuberculosis cases?

<p>HIV/AIDS epidemic (A)</p> Signup and view all the answers

What is the most effective way to prevent the transmission of Salmonella?

<p>Cooking food thoroughly (B)</p> Signup and view all the answers

What are the two surface glycoproteins found in influenza viruses and how many subtypes do they occur in?

<p>Hemagglutinin (HA) and neuraminidase (NA), occurring in 16H and 9N subtypes respectively (B)</p> Signup and view all the answers

What is the estimated loss due to the negative economic impact on trade, travel, and tourism caused by influenza?

<p>$30 to $150 billion (B)</p> Signup and view all the answers

What is the difference between antigenic shift and antigenic drift?

<p>Antigenic shift is a major change in the influenza A virus that results in a new subtype, while antigenic drift is a minor change in the virus that occurs gradually over time (A)</p> Signup and view all the answers

What is the most common subtype of hemagglutinin and neuraminidase found in humans?

<p>H3 and N1 (A)</p> Signup and view all the answers

Which influenza pandemic resulted in the highest number of deaths?

<p>Spanish flu (H1N1) (D)</p> Signup and view all the answers

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Study Notes

SARS (Severe Acute Respiratory Syndrome)

  • The main reservoir for SARS-COV-1 is believed to be bats.
  • SARS transmission occurs through close contact with an infected individual, primarily through respiratory droplets and contact with contaminated surfaces.

SARS Epidemiology

  • The fatality rate of SARS is approximately 9.6%.

SARS Pathogenesis

  • SARS pathogenesis involves the virus binding to ACE2 receptors on lung cells, leading to inflammation, immune responses, and cell damage.

SARS Treatment

  • The recommended therapy for SARS typically involves antiviral medications, corticosteroids, and supportive care.

Mycobacterial Infections

  • Tuberculosis (TB) is the most common disease caused by Mycobacterial infections.
  • TB is the leading cause of death among infectious diseases worldwide.

Tuberculosis Control

  • The most effective way to eliminate reservoirs of tuberculosis is through a combination of early detection, treatment, and vaccination efforts.
  • The possible cause of the increase in tuberculosis cases is attributed to factors such as HIV/AIDS, poverty, and inadequate healthcare infrastructure.

Salmonella Prevention

  • The most effective way to prevent the transmission of Salmonella is through proper food handling, cooking, and hygiene practices.

Influenza Viruses

  • The two surface glycoproteins found in influenza viruses are Hemagglutinin (HA) and Neuraminidase (NA), which occur in 18 HA and 11 NA subtypes, respectively.
  • The estimated loss due to the negative economic impact on trade, travel, and tourism caused by influenza is approximately $10 billion annually.

Influenza Evolution

  • Antigenic shift occurs when two or more different influenza viruses infect a host cell, resulting in a new virus with a unique combination of genes.
  • Antigenic drift occurs when an influenza virus undergoes gradual, incremental changes in its surface proteins.
  • The most common subtype of hemagglutinin and neuraminidase found in humans is H1N1.
  • The 1918 Spanish flu pandemic resulted in the highest number of deaths, with an estimated 50-100 million fatalities.

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