Podcast
Questions and Answers
What is the main reservoir for SARS-COV-1?
What is the main reservoir for SARS-COV-1?
- Dogs
- Cats
- Bats (correct)
- Pigs
What is the transmission mode of SARS?
What is the transmission mode of SARS?
- Sexual transmission
- Vector-borne
- Contact with bodily fluids
- Droplet aerosol and fomite deposited on the respiratory mucosal epithelium (correct)
What is the fatality rate of SARS?
What is the fatality rate of SARS?
- 20%
- 1%
- 5%
- 10% (correct)
What is the pathogenesis of SARS?
What is the pathogenesis of SARS?
What is the recommended therapy for SARS?
What is the recommended therapy for SARS?
What is the most common disease caused by Mycobacterial infections?
What is the most common disease caused by Mycobacterial infections?
What is the leading cause of death among infectious diseases worldwide?
What is the leading cause of death among infectious diseases worldwide?
What is the most effective way to eliminate reservoirs of tuberculosis?
What is the most effective way to eliminate reservoirs of tuberculosis?
What is the possible cause of the increase in tuberculosis cases?
What is the possible cause of the increase in tuberculosis cases?
What is the most effective way to prevent the transmission of Salmonella?
What is the most effective way to prevent the transmission of Salmonella?
What are the two surface glycoproteins found in influenza viruses and how many subtypes do they occur in?
What are the two surface glycoproteins found in influenza viruses and how many subtypes do they occur in?
What is the estimated loss due to the negative economic impact on trade, travel, and tourism caused by influenza?
What is the estimated loss due to the negative economic impact on trade, travel, and tourism caused by influenza?
What is the difference between antigenic shift and antigenic drift?
What is the difference between antigenic shift and antigenic drift?
What is the most common subtype of hemagglutinin and neuraminidase found in humans?
What is the most common subtype of hemagglutinin and neuraminidase found in humans?
Which influenza pandemic resulted in the highest number of deaths?
Which influenza pandemic resulted in the highest number of deaths?
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Study Notes
SARS (Severe Acute Respiratory Syndrome)
- The main reservoir for SARS-COV-1 is believed to be bats.
- SARS transmission occurs through close contact with an infected individual, primarily through respiratory droplets and contact with contaminated surfaces.
SARS Epidemiology
- The fatality rate of SARS is approximately 9.6%.
SARS Pathogenesis
- SARS pathogenesis involves the virus binding to ACE2 receptors on lung cells, leading to inflammation, immune responses, and cell damage.
SARS Treatment
- The recommended therapy for SARS typically involves antiviral medications, corticosteroids, and supportive care.
Mycobacterial Infections
- Tuberculosis (TB) is the most common disease caused by Mycobacterial infections.
- TB is the leading cause of death among infectious diseases worldwide.
Tuberculosis Control
- The most effective way to eliminate reservoirs of tuberculosis is through a combination of early detection, treatment, and vaccination efforts.
- The possible cause of the increase in tuberculosis cases is attributed to factors such as HIV/AIDS, poverty, and inadequate healthcare infrastructure.
Salmonella Prevention
- The most effective way to prevent the transmission of Salmonella is through proper food handling, cooking, and hygiene practices.
Influenza Viruses
- The two surface glycoproteins found in influenza viruses are Hemagglutinin (HA) and Neuraminidase (NA), which occur in 18 HA and 11 NA subtypes, respectively.
- The estimated loss due to the negative economic impact on trade, travel, and tourism caused by influenza is approximately $10 billion annually.
Influenza Evolution
- Antigenic shift occurs when two or more different influenza viruses infect a host cell, resulting in a new virus with a unique combination of genes.
- Antigenic drift occurs when an influenza virus undergoes gradual, incremental changes in its surface proteins.
- The most common subtype of hemagglutinin and neuraminidase found in humans is H1N1.
- The 1918 Spanish flu pandemic resulted in the highest number of deaths, with an estimated 50-100 million fatalities.
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