Salivary Gland Tumors Overview

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Questions and Answers

What is the most common benign tumor of salivary glands?

  • Canalicular Adenoma
  • Basal Cell Adenoma
  • Pleomorphic Adenoma (correct)
  • Warthin Tumor

Which of the following tumors is typically associated with smoking as a risk factor?

  • Adenoid Cystic Carcinoma
  • Mucoepidermoid Carcinoma
  • Warthin Tumor (correct)
  • Acinic Cell Carcinoma

Which malignant tumor is most commonly found in the major salivary glands?

  • Carcinoma ex-pleomorphic adenoma
  • Acinic Cell Carcinoma
  • Mucoepidermoid Carcinoma (correct)
  • Adenoid Cystic Carcinoma

What is a distinguishing clinical feature of Adenoid Cystic Carcinoma compared to Pleomorphic Adenoma?

<p>Presence of painful symptoms (C)</p> Signup and view all the answers

What age group is primarily affected by Mucoepidermoid Carcinoma?

<p>40-50 years old (A)</p> Signup and view all the answers

Which type of salivary gland tumor is typically bilateral?

<p>Warthin Tumor (A)</p> Signup and view all the answers

Which malignant tumor is known for a poor prognosis and a high rate of local recurrence?

<p>Adenoid Cystic Carcinoma (A)</p> Signup and view all the answers

What type of cells are primarily found in Mucoepidermoid Carcinoma?

<p>Squamous, mucous, and intermediate cells (D)</p> Signup and view all the answers

Which salivary gland tumor is characterized by a well-defined encapsulation and presents as a painless rubbery swelling?

<p>Pleomorphic Adenoma (C)</p> Signup and view all the answers

What is the histological characteristic of Acinic Cell Carcinoma?

<p>Presence of large cells with granular basophilic cytoplasm (A)</p> Signup and view all the answers

Flashcards

What is a pleomorphic adenoma?

Benign tumor originating from epithelial tissue, not mixed origin. Most common salivary gland tumor, characterized by slow growth, well-defined capsule, painless swelling, and rubbery texture on palpation.

What is a canalicular adenoma?

Benign tumor of salivary glands, commonly found in the upper lip and parotid gland. Characterized by small, well-defined nodules that may cause slight swelling.

What is a Warthin tumor?

Second most common salivary gland tumor, originating in parotid gland. Primarily affects smokers, characterized by slow growth, soft or rubbery texture, and usually painless. It often presents bilaterally, meaning it occurs in both parotid glands.

What is a mucoepidermoid carcinoma?

Most common malignant tumor of the salivary glands, affecting major glands, particularly the parotid gland. Characterized by similar features to pleomorphic adenoma but can demonstrate signs of malignancy such as ulceration, necrosis, invasion, and potential for facial paralysis.

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What is an adenoid cystic carcinoma?

Second most common malignant salivary gland tumor, with high risk of recurrence, mainly affecting minor salivary glands. Characterized by pain, ulceration, and facial paralysis.

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What is an acinic cell carcinoma?

Rare malignant tumor primarily found in the parotid gland. Characterized by slow growth, well-defined capsule, and painless swelling but with a higher risk of recurrence.

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What is a carcinoma ex-pleomorphic adenoma?

Malignant tumor arising from a pre-existing pleomorphic adenoma, typically after 10-15 years or following a local recurrence. Characterized by signs of malignancy such as pain, paralysis, and ulceration, predominantly affecting the parotid gland.

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What is a basal cell adenoma?

Benign tumor, less common than pleomorphic adenoma, found in the parotid and superior lip. Characterized by slow growth, well-defined capsule, and painless swelling.

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What is an oncocytoma?

Benign tumor found mostly in the parotid gland, characterized by slow growth, well-defined capsule, and painless swelling. It's often bilateral and can cause facial paralysis.

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What are ductal papillomas?

Rare benign growth found in the salivary glands, characterized by papillary structures protruding into the ductal lumen. It may be asymptomatic or cause swelling and discharge.

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Study Notes

Salivary Gland Tumors

  • Benign Tumors (Adenomas):
    • Pleomorphic Adenoma (Mixed Tumor): Most common, slow-growing, well-defined, painless, rubbery swelling on palpation, often in parotid gland. Can be unilocular or multilocular, with a fibrous capsule that can be deficient, leading to recurrence.
    • Warthin Tumor (Adenolymphoma): Second most common, bilateral, slow-growing, painless, often parotid gland. Originates from epithelial tissue with lymph node involvement, not a lymphoma. Associated with smoking.
    • Canalicular Adenoma: Common in upper lip, rare in parotid, slow-growing swelling.
    • Basal Cell Adenoma: 1-2% of cases, seen in parotid, often in the upper lip.
    • Oncocytoma: Eosinophilic, bilateral, parotid-favored.

Malignant Tumors (Carcinomas)

  • Mucoepidermoid Carcinoma: Most common malignant salivary gland tumor in the major glands, often in parotid. Can present clinically like a benign tumor but can progress to malignancy.
  • Adenoid Cystic Carcinoma: Second most common, often in minor salivary glands, especially in the palate, potentially involves nerves causing pain, anesthesia, and paresthesia.
  • Acinic Cell Carcinoma: Rare, primarily parotid, any age, large granular basophilic cells in acinar formations. Can be slow-growing and initially seem benign.
  • Carcinoma Ex-Pleomorphic Adenoma: Develops in a pre-existing pleomorphic adenoma after a long period. Characterized by a malignant component growing from a benign tumor. Increased risk of local recurrence.

Additional Notes

  • Clinical Features: Swelling (slow or fast), pain (often absent in benign tumors), presence of ulcer or neural signs (important for malignant tumors).
  • Histological Features: Important for diagnosis. Differentiates benign from malignant based on cell types, arrangement, presence of capsule, invasion into surrounding tissue.
  • Prognosis: Can range from poor to good, depending on type, location, spread to lymph nodes, etc. Local recurrence in tumors with capsule deficiency is common.

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