Salbutamol and Beta2-Adrenoceptor Quiz
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Questions and Answers

What is the primary mediator of the second phase of asthmatic attacks?

  • Histamine (correct)
  • Mucous
  • Acetylcholine
  • Bronchial smooth muscle
  • Why is a low FEV1 considered a useful metric of airflow limitation?

  • It directly measures the amount of acetylcholine in the lungs.
  • It correlates with a decrease in mucus production.
  • It indicates bronchoconstriction. (correct)
  • It reflects an increase in histamine levels.
  • What is the purpose of pharmacological control of bronchial smooth muscle tone?

  • To minimize side effects of drugs (correct)
  • To increase systemic exposure to drugs
  • To induce hyperinflation of the lungs
  • To promote mucus retention in the airways
  • What is the advantage of inhalation of drugs for airflow limitation compared to oral administration?

    <p>Reduced side effects (B)</p> Signup and view all the answers

    Which method maximizes drug inhalation during inhaler use?

    <p>Use of spacer (A)</p> Signup and view all the answers

    Which statement regarding Salbutamol is FALSE?

    <p>Salbutamol should be given intravenously (A)</p> Signup and view all the answers

    What is the primary mechanism of action of muscarinic receptor antagonists like ipratropium bromide?

    <p>Inhibition of muscarinic receptors (D)</p> Signup and view all the answers

    Which condition are methylxanthines such as theophylline and aminophylline more commonly used for?

    <p>COPD (A)</p> Signup and view all the answers

    What is a common side effect associated with methylxanthines like theophylline?

    <p>Nausea (B)</p> Signup and view all the answers

    Which drug combination shows an additive effect on change in FEV1?

    <p>Ipratropium bromide and albuterol (salbutamol) (B)</p> Signup and view all the answers

    Which statement about the effect of selective Beta2 adrenoceptor agonists on Beta1 receptors is TRUE?

    <p>They have no action on Beta1 receptors (C)</p> Signup and view all the answers

    Which of the following is not a common trigger for asthma?

    <p>Bacterial infections (B)</p> Signup and view all the answers

    What is the primary cause of chronic obstructive pulmonary disease (COPD)?

    <p>Cigarette smoking (B)</p> Signup and view all the answers

    Which class of bronchodilator drugs acts on β-adrenoceptors?

    <p>β-Adrenoceptor agonists (D)</p> Signup and view all the answers

    What is the distinguishing feature between asthma and COPD in terms of lung function?

    <p>COPD causes chest hyperinflation while asthma does not (B)</p> Signup and view all the answers

    Which term describes the episodic bouts of airflow limitation seen in asthma?

    <p>Bronchospasm (A)</p> Signup and view all the answers

    Why is chronic obstructive pulmonary disease (COPD) considered irreversible?

    <p>Irreversible damage to the airways and lung function loss occur (A)</p> Signup and view all the answers

    Which type of adrenoceptor agonist is salbutamol?

    <p>Beta2 (A)</p> Signup and view all the answers

    What is the main side effect related to the stimulation of Beta1 receptors by salbutamol and terbutaline?

    <p>Tachycardia (C)</p> Signup and view all the answers

    Why is regularly scheduled use of short-acting adrenoceptor agonists generally not recommended?

    <p>May increase airway hyperresponsiveness (C)</p> Signup and view all the answers

    Which long-acting β-adrenoceptor agonist has a slower onset of action?

    <p>Salmeterol (A)</p> Signup and view all the answers

    What caution should be taken with long-acting β-adrenoceptor agonists like salmeterol?

    <p>May decrease responsiveness to short-acting Beta2 agonists (A)</p> Signup and view all the answers

    What is the most effective medication for the relief of acute bronchospasm?

    <p>Salbutamol (C)</p> Signup and view all the answers

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