Salbutamol and Beta2-Adrenoceptor Quiz

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What is the primary mediator of the second phase of asthmatic attacks?

Histamine (correct)

Mucous

Acetylcholine

Bronchial smooth muscle

Why is a low FEV1 considered a useful metric of airflow limitation?

It directly measures the amount of acetylcholine in the lungs.

It correlates with a decrease in mucus production.

It indicates bronchoconstriction. (correct)

It reflects an increase in histamine levels.

What is the purpose of pharmacological control of bronchial smooth muscle tone?

To minimize side effects of drugs (correct)

To increase systemic exposure to drugs

To induce hyperinflation of the lungs

To promote mucus retention in the airways

What is the advantage of inhalation of drugs for airflow limitation compared to oral administration?

Reduced side effects Signup and view all the answers

Which method maximizes drug inhalation during inhaler use?

Use of spacer Signup and view all the answers

Which statement regarding Salbutamol is FALSE?

Salbutamol should be given intravenously Signup and view all the answers

What is the primary mechanism of action of muscarinic receptor antagonists like ipratropium bromide?

Inhibition of muscarinic receptors Signup and view all the answers

Which condition are methylxanthines such as theophylline and aminophylline more commonly used for?

COPD Signup and view all the answers

What is a common side effect associated with methylxanthines like theophylline?

Nausea Signup and view all the answers

Which drug combination shows an additive effect on change in FEV1?

Ipratropium bromide and albuterol (salbutamol) Signup and view all the answers

Which statement about the effect of selective Beta2 adrenoceptor agonists on Beta1 receptors is TRUE?

They have no action on Beta1 receptors Signup and view all the answers

Which of the following is not a common trigger for asthma?

Bacterial infections Signup and view all the answers

What is the primary cause of chronic obstructive pulmonary disease (COPD)?

Cigarette smoking Signup and view all the answers

Which class of bronchodilator drugs acts on β-adrenoceptors?

β-Adrenoceptor agonists Signup and view all the answers

What is the distinguishing feature between asthma and COPD in terms of lung function?

COPD causes chest hyperinflation while asthma does not Signup and view all the answers

Which term describes the episodic bouts of airflow limitation seen in asthma?

Bronchospasm Signup and view all the answers

Why is chronic obstructive pulmonary disease (COPD) considered irreversible?

Irreversible damage to the airways and lung function loss occur Signup and view all the answers

Which type of adrenoceptor agonist is salbutamol?

Beta2 Signup and view all the answers

What is the main side effect related to the stimulation of Beta1 receptors by salbutamol and terbutaline?

Tachycardia Signup and view all the answers

Why is regularly scheduled use of short-acting adrenoceptor agonists generally not recommended?

May increase airway hyperresponsiveness Signup and view all the answers

Which long-acting β-adrenoceptor agonist has a slower onset of action?

Salmeterol Signup and view all the answers

What caution should be taken with long-acting β-adrenoceptor agonists like salmeterol?

May decrease responsiveness to short-acting Beta2 agonists Signup and view all the answers

What is the most effective medication for the relief of acute bronchospasm?

Salbutamol Signup and view all the answers