8 Questions
Which term is often used to integrate all the processes of distribution, biotransformation, and elimination?
Disposition
Which form of a substance is generally passively absorbed across a membrane?
Non-ionized form
In disposition models, what is the term used for areas of the body where a chemical may go to?
Compartments
Which model describes the disposition of a substance introduced and distributed instantaneously and evenly in the body?
One-compartment open model
What area of the body is considered a compartment in disposition models?
Blood
In kinetic models, what is proportional to the amount left in the body in a first-order rate process?
Concentration in blood
Which process involves a toxicant moving within the body with time according to kinetic models?
Distribution
'One-compartment open model' describes the disposition of a substance that is:
Distributed evenly in the body
Test your knowledge on the different routes of drug exposure, including intraperitoneal, intramuscular, subcutaneous, intradermal, and intravenous, as well as the concept of bioavailability. Learn about factors affecting drug absorption and bioavailability.
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