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Questions and Answers
Which route of drug administration is suitable for drugs destroyed by gastrointestinal enzymes?
What is the advantage of the buccal route of drug administration?
In which condition is the gastric gavage route commonly used?
Which route of drug administration offers 100% bioavailability?
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What is the disadvantage of the oral route of drug administration?
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Study Notes
Routes of Drug Administration
- Parenteral route is suitable for drugs destroyed by gastrointestinal enzymes, as it bypasses the digestive system.
- The advantage of the buccal route of drug administration is that it allows for rapid absorption of the drug into the bloodstream, while avoiding hepatic first-pass metabolism.
- The gastric gavage route is commonly used in research involving animals, particularly in toxicology studies.
- The intravenous (IV) route offers 100% bioavailability, as the drug is directly injected into the bloodstream.
- The disadvantage of the oral route of drug administration is that it is susceptible to hepatic first-pass metabolism and degradation by gastrointestinal enzymes, which can reduce the bioavailability of the drug.
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Description
Test your knowledge of different routes of drug administration including enteral, parenteral, respiratory, and topical methods. This quiz covers advantages, disadvantages, contraindications, and specific examples of drug administration routes.
