Rosalind Franklin and DNA
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Questions and Answers

What pivotal insight regarding DNA's structure did Rosalind Franklin provide through Photograph 51?

  • DNA forms a double helix structure. (correct)
  • DNA is composed of four strands intertwined.
  • The backbone of DNA lies on the inside of the molecule.
  • DNA has a triple helix structure.

Which significant contribution of Rosalind Franklin went unrecognized during her lifetime regarding DNA?

  • She directly collaborated with Crick and Watson.
  • She discovered the nucleotide sequences in DNA.
  • Her X-ray photograph established the triple helix model.
  • Her data supported the confirmation of the double helix model. (correct)

After moving to Birkbeck College in 1953, which virus's structure did Franklin propose a new groundbreaking model for?

  • Influenza virus
  • Ebola virus
  • Tobacco mosaic virus (correct)
  • Rabies virus

In which university did Maurice Wilkins primarily conduct his X-ray studies on DNA?

<p>King's College, London (D)</p> Signup and view all the answers

What significant event occurred in 1952 involving Rosalind Franklin's research on DNA?

<p>She captured the first clear image of DNA structure. (D)</p> Signup and view all the answers

Which of the following describes Franklin's proposed DNA molecule structure, contrary to other beliefs at her time?

<p>A double-strand helix with external backbone (A)</p> Signup and view all the answers

What obstacle did Rosalind Franklin face with her DNA research recognition compared to her male peers?

<p>Her death preceded the awarding of the Nobel Prize (D)</p> Signup and view all the answers

Which aspect of the polio virus research was acknowledged posthumously with connection to Franklin?

<p>Confirmation of its crystalline structure (A)</p> Signup and view all the answers

Who was bequeathed funds by Rosalind Franklin for further scientific research?

<p>Aaron Klug (B)</p> Signup and view all the answers

What was the hallmark achievement of Wilkins that led to him sharing the Nobel Prize with Watson and Crick?

<p>His X-ray diffraction studies on DNA fibers (C)</p> Signup and view all the answers

Flashcards

Photograph 51

The first clear X-ray image of DNA's crystalline structure, deemed crucial in science.

Rosalind Franklin

A scientist who conducted DNA research and created the first clear DNA image.

Double helix

The confirmed structure of DNA identified as two intertwined strands.

Maurice Wilkins

Nobel Prize-winning biophysicist known for his work on DNA structure using X-ray techniques.

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Birkbeck College

Where Franklin studied virus structures after her DNA research.

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Tobacco mosaic virus (TMV)

A virus whose molecular structure model was proposed by Franklin and later validated.

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Nobel Prize 1962

Awarded to Watson, Crick, and Wilkins for DNA structure, excluding Franklin.

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Untimely death

Franklin's early passing in 1958, leading to missed recognition for her work.

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Polio virus structure

Franklin's work on polio's crystalline structure gained acknowledgment posthumously in 1959.

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X-ray imaging

Technique used by Franklin and Wilkins to study DNA and molecular structures.

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Study Notes

DNA X-Ray Photography

  • Photograph 51, produced the first clear image of DNA's crystalline structure
  • This image was heralded as one of science's most important photographs
  • This photograph took 60 hours to produce

Rosalind Franklin's Contribution

  • Franklin constructed her own 3D model of DNA at King's College, London
  • Franklin refined X-ray techniques to study DNA's structure.
  • In 1952, Franklin produced the first clear image of DNA's structure
  • The image, labeled Photograph 51, revealed DNA was a helix composed of two strands

Significance of Franklin's Work

  • Franklin's work was crucial to understanding the structure of DNA
  • Her research revealed the double helix structure of DNA.
  • Franklin's critical role in discovering DNA's structure
  • Her work significantly contributed to significant discoveries in virology

Recognition and Awards

  • Franklin's significant scientific discoveries were largely unrecognized during her lifetime.
  • The structure of DNA was confirmed only after her death in 1958
  • Her work on polio viruses was also recognized posthumously
  • She received a $13,000 grant to study the polio virus
  • Another $4,000 was bequeathed to support a scientist's work

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Description

Explore the groundbreaking work of Rosalind Franklin in revealing the structure of DNA through X-ray photography. This quiz covers her significant contributions, including the famous Photograph 51, and the impact of her research on science. Test your knowledge on the history and significance of her findings in molecular biology.

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