Role of T Cells in Organ-Specific Autoimmune Diseases
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Questions and Answers

Which type of antibodies are used to treat psoriasis?

  • Monoclonal antibodies that block IL-17 (correct)
  • Monoclonal antibodies that block TNF
  • Monoclonal antibodies that block IL-2
  • Monoclonal antibodies that block IL-6 receptor

    • Which signaling molecule is targeted by small molecule inhibitors to treat rheumatoid arthritis?

  • IL-17
  • Janus kinase 3 (JAK3) (correct)
  • IL-6 receptor
  • TNF

    • Which type of drugs block costimulators to inhibit T cell responses?

  • Drugs that block TNF
  • Monoclonal antibodies
  • Drugs that block B7 (correct)
  • Small molecule inhibitors

    • Which cells are believed to be the cause of many organ-specific autoimmune diseases in humans?

    <p>T cells</p> Signup and view all the answers

    Why are autoimmune diseases typically chronic and progressive?

    <p>Because T cells generate long-lived memory cells</p> Signup and view all the answers

    What is epitope spreading in the context of autoimmune diseases?

    <p>The spread of immune response to include many self antigens</p> Signup and view all the answers

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