Role of T Cells in Organ-Specific Autoimmune Diseases

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Which type of antibodies are used to treat psoriasis?

Monoclonal antibodies that block IL-17

Which signaling molecule is targeted by small molecule inhibitors to treat rheumatoid arthritis?

Janus kinase 3 (JAK3)

Which type of drugs block costimulators to inhibit T cell responses?

Drugs that block B7

Which cells are believed to be the cause of many organ-specific autoimmune diseases in humans?

<p>T cells</p> Signup and view all the answers

Why are autoimmune diseases typically chronic and progressive?

<p>Because T cells generate long-lived memory cells</p> Signup and view all the answers

What is epitope spreading in the context of autoimmune diseases?

<p>The spread of immune response to include many self antigens</p> Signup and view all the answers

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