Role of Antigen Presenting Cells in Immune Response
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Questions and Answers

Which cells are responsible for the uptake of antigens in secondary lymphoid tissues?

  • T cells
  • Follicular dendritic cells (FDCs)
  • Dendritic cells (DCs) (correct)
  • Macrophages
  • Where can immune complexes be found in relation to follicular dendritic cells (FDCs)?

  • Internalized within FDCs
  • On the surface of FDCs (correct)
  • In the cytoplasm of FDCs
  • Within the nucleus of FDCs
  • How do T and B cells enter the spleen in relation to the delivery of antigens?

  • Via central arteriole (correct)
  • Through the lymphatic system
  • By crossing the blood-brain barrier
  • Through specialized exocytosis
  • Where do T and B cells migrate to after leaving the marginal sinus in the spleen?

    <p>Paracortex</p> Signup and view all the answers

    What structures serve as anatomic crossroads for interactions of antigens and lymphocytes?

    <p>Lymph nodes</p> Signup and view all the answers

    How do lymphocytes mainly enter lymph nodes from the blood?

    <p>Via specialized blood vessels named high endothelial venules (HEVs)</p> Signup and view all the answers

    What is the primary function of plasmacytoid dendritic cells (pDCs) in the immune system?

    <p>Producing type I interferons in response to viral infection</p> Signup and view all the answers

    Which type of dendritic cell is known for residing in the epidermis of the skin and has dendritic morphology?

    <p>Langerhans cell</p> Signup and view all the answers

    What is the main function of conventional dendritic cells (cDCs) in nonlymphoid tissues?

    <p>Delivering antigens to T cells in lymphoid tissues</p> Signup and view all the answers

    Which type of dendritic cell is responsible for antigen cross-presentation?

    <p>Langerhans cell</p> Signup and view all the answers

    Where are T-cell responses initiated within the immune system?

    <p>In secondary lymphoid organs by activated dendritic cells</p> Signup and view all the answers

    What distinguishes plasmacytoid dendritic cells (pDCs) from conventional dendritic cells?

    <p>Acting as sentinels in early defense against viral infection</p> Signup and view all the answers

    What is the main function of the white pulp in the spleen?

    <p>Mediate adaptive immune response</p> Signup and view all the answers

    Which area in the spleen is mainly concentrated with follicular dendritic cells (FDCs)?

    <p>B cell zone</p> Signup and view all the answers

    What is the primary role of follicular dendritic cells (FDCs) in the immune response?

    <p>Capture of antigens in immune complexes</p> Signup and view all the answers

    Where do both antigens and lymphocytes enter the spleen from?

    <p>Blood stream</p> Signup and view all the answers

    Which type of cells are follicular dendritic cells (FDCs) NOT derived from?

    <p>Bone marrow precursors</p> Signup and view all the answers

    What do follicular dendritic cells (FDCs) form on their dendrites to capture antigens?

    <p>Beads</p> Signup and view all the answers

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