The Role of Th2 Cells in Parasitic Worm Infections

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Questions and Answers

Which cells produce Th2 cytokines and provide help for antibody production?

  • Classical Th2 cells
  • Tfh cells (correct)
  • Effector T lymphocytes
  • Dendritic cells

What response is activated by IL-5 and is important in the destruction of helminths?

  • Activation of eosinophils (correct)
  • Activation of dendritic cells
  • Activation of macrophages
  • Activation of natural killer cells

Which cytokines induce the development of antigen-activated CD4+ T cells into Th1, Th2, and Th17 subsets?

  • Transforming growth factor β
  • IL-5
  • IL-12 (correct)
  • Interferon-γ

Which cells are induced by parasitic worm infections and promote the destruction of these parasites?

<p>Th2 cells (D)</p> Signup and view all the answers

Which cytokines function cooperatively in eradicating worm infections?

<p>IL-4, IL-5, and IL-13 (A)</p> Signup and view all the answers

What is the role of IL-4 in the destruction of helminths?

<p>Stimulates the production of IgE antibodies (C)</p> Signup and view all the answers

Which type of macrophage response is involved in tissue repair following injury and may contribute to fibrosis in disease states?

<p>Alternative macrophage activation (C)</p> Signup and view all the answers

What type of cells are involved in allergic reactions to environmental antigens?

<p>Th2 cells (A)</p> Signup and view all the answers

Which cytokines act on B cells to stimulate the production of IgE antibodies?

<p>IL-4 and IL-13 (D)</p> Signup and view all the answers

What determines the outcome of an infection caused by the protozoan parasite Leishmania major?

<p>Activation of Th1 cells (A)</p> Signup and view all the answers

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