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Role of GAA in Brain Metabolism and Heat Stress
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Role of GAA in Brain Metabolism and Heat Stress

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Questions and Answers

What is the impact of creatine monohydrate and guanidinoacetic acid supplementation on the growth performance of finishing pigs?

  • It decreases the growth performance
  • It has no effect on the growth performance
  • It is dependent on the breed of pigs
  • It increases the growth performance (correct)
  • What is the primary function of creatine in the body?

  • To regulate creatine transport (correct)
  • To improve bone health
  • To increase muscle mass
  • To enhance cardiovascular function
  • What is the effect of guanidinoacetic acid on the methylation cycle?

  • It has an alternative mechanism to affect the methylation cycle (correct)
  • It has no effect on the methylation cycle
  • It increases the methylation cycle
  • It decreases the methylation cycle
  • What is the role of guanidinoacetic acid in advanced physiological processes?

    <p>It has a role in muscle growth and other physiological processes</p> Signup and view all the answers

    What is the impact of dietary guanidinoacetic acid on the skeletal muscle development of finishing pigs?

    <p>It improves skeletal muscle development</p> Signup and view all the answers

    What is the effect of co-administration of creatine and guanidinoacetic acid on tissue bioenergetics?

    <p>It has a novel approach to augment tissue bioenergetics</p> Signup and view all the answers

    What is the impact of heat stress on poultry production?

    <p>It decreases poultry production</p> Signup and view all the answers

    What is the effect of creatine supplementation on the growth performance of finishing pigs?

    <p>It increases the growth performance</p> Signup and view all the answers

    What is the role of guanidinoacetic acid in meat production and quality?

    <p>It plays a role in both meat production and quality</p> Signup and view all the answers

    What is the effect of dietary guanidinoacetic acid on the myogenic gene expression of finishing pigs?

    <p>It changes myogenic gene expression</p> Signup and view all the answers

    Study Notes

    Guanidinoacetic Acid (GAA) and Creatine

    • GAA is an amino acid derivative and precursor to creatine, which plays a significant role in energy metabolism.
    • GAA has been explored as an effective alternative to creatine supplements due to creatine's instability during manufacturing and cost.

    Effects of GAA on Brain Function

    • Increased dietary GAA can increase brain functions and concentration in broilers subjected to heat stress.
    • GAA supplementation can increase plasma arginine, making it more readily available for metabolic processes other than de novo GAA production.

    GAA Supplementation in Poultry

    • Dietary GAA can be used to substitute 150% of arginine in broiler diets with a moderately low crude protein to achieve comparable growth, meat quality, and creatine production.
    • GAA supplementation can spare dietary arginine, and supplementing with 1.2 g/kg GAA is the most effective way to boost growth performance.
    • GAA supplementation does not affect feed intake in broilers, except at very high doses (6 g/kg) which lead to reduced feed intake.
    • Adding coenzyme Q10, taurine, or a combination of the two in broiler diets can improve growth performance.

    GAA Supplementation in Swine

    • Feeding GAA during gestation and lactation improves multiparity and gilt performance, milk quality, and production, as well as litter growth performance.
    • GAA supplementation can be used as an arginine-sparing agent in animals, improving growth, feed efficiency, and growth performance.

    Other Effects of GAA

    • GAA supplementation can act as an arginine-sparing agent while decreasing mortality related to ascites.
    • GAA can improve skeletal muscle development and expression of myogenic genes.
    • GAA can be used to replace arginine in animal diets.

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    Description

    Exploring the effects of glycine amino acid on brain function and concentration in broilers under heat stress, and its relation to arginine and creatine.

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