Brain Metabolism and Vitamin Deficiencies
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Questions and Answers

What is the role of PDH kinase in regulating PDH complex activity?

  • It has no effect on PDH
  • It activates PDH
  • It deactivates PDH (correct)
  • It regulates the activity of PDH phosphatase

Which vitamin deficiency can cause Wernicke-Korsakoff syndrome?

  • Vitamin B3
  • Vitamin B1 (correct)
  • Vitamin B2
  • Vitamin B5

What is the effect of ATP on PDH kinase activity?

  • It has no effect on PDH kinase
  • It inhibits PDH phosphatase
  • It activates PDH kinase
  • It deactivates PDH kinase (correct)

What is the effect of pyruvate on PDH complex activity?

<p>It deactivates PDH (D)</p> Signup and view all the answers

Which of the following is a positive allosteric regulator of PDH phosphatase?

<p>Ca2+ (B)</p> Signup and view all the answers

What is the consequence of PDH complex inactivity in brain cells?

<p>Decreased ATP production (A)</p> Signup and view all the answers

What is the cause of Wernicke-Korsakoff syndrome?

<p>Thiamine deficiency (B)</p> Signup and view all the answers

What is the role of PDH phosphatase in regulating PDH complex activity?

<p>It activates PDH (D)</p> Signup and view all the answers

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