Rodak's Hematology: Hemostasis Part I Quiz
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Questions and Answers

Which of the following is a screening test for assessing deficiencies in factors II, V, VII, and X?

  • Platelet count
  • Prothrombin time (correct)
  • Partial thromboplastin time
  • Thrombin time
  • In which disorder is the platelet aggregation abnormal in response to ristocetin?

  • Bernard-Soulier syndrome (BSS)
  • Glanzmann's thrombasthenia
  • von Willebrand disease (VWD) (correct)
  • Storage pool defect
  • Which of the following is a hereditary coagulopathy that manifests during infancy or early in life?

  • Hemophilia A (correct)
  • Disseminated intravascular coagulation (DIC)
  • Vitamin K deficiency
  • Acquired hemophilia
  • In which disorder is clot retraction absent?

    <p>Bernard-Soulier syndrome (BSS)</p> Signup and view all the answers

    Which of the following tests assesses for hypofibrinogenemia and dysfibrinogenemia?

    <p>Thrombin time</p> Signup and view all the answers

    Which of the following is an acquired coagulopathy that manifests during adulthood?

    <p>Disseminated intravascular coagulation (DIC)</p> Signup and view all the answers

    What is the main function of secondary hemostasis in the body?

    <p>To reinforce the unstable platelet plug with chemically stable fibrin</p> Signup and view all the answers

    Which enzyme is responsible for transforming soluble fibrinogen to insoluble fibrin in secondary hemostasis?

    <p>Thrombin</p> Signup and view all the answers

    What components are involved in determining the equilibrium between bleeding and clotting in hemostasis?

    <p>Platelets, vascular endothelial cells, and coagulation proteins</p> Signup and view all the answers

    In secondary hemostasis, what is the role of thrombin?

    <p>Generates fibrin from fibrinogen to stabilize the platelet plug</p> Signup and view all the answers

    Which phase of hemostasis involves clot (fibrin) dissolution and vessel repair?

    <p>Primary hemostasis</p> Signup and view all the answers

    What is the endpoint of the enzyme-mediated reactions in secondary hemostasis?

    <p>Generation of thrombin</p> Signup and view all the answers

    What is the usual clinical sign of vascular disorders?

    <p>Tendency to bruise easily or bleed spontaneously</p> Signup and view all the answers

    Which laboratory studies are usually normal in patients with vascular disorders?

    <p>Both platelets and blood coagulation</p> Signup and view all the answers

    What is the basis for diagnosing hereditary hemorrhagic telangiectasia?

    <p>Family history of a similar disorder</p> Signup and view all the answers

    Which condition is characterized by obvious hemorrhages into the skin and mucous membranes?

    <p>Purpura</p> Signup and view all the answers

    Which vascular disorder is associated with cherry-red hemangiomas, ataxia-telangiectasia, and chronic actinic telangiectasia?

    <p>Hereditary hemorrhagic telangiectasia</p> Signup and view all the answers

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