Questions and Answers
What is the generic name for Rocephin?
Rocephin belongs to the class of drugs known as ______.
anti-infectives
What infections is Rocephin used to treat?
Skin and skin structure infections, urinary and gynecologic infections, respiratory tract infections, meningitis, bone/joint infections, intra-abdominal infections and septicemia, otitis media, perioperative prophylaxis, Lyme disease.
How does Rocephin work?
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How is Rocephin metabolized and excreted?
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What are some common side effects of Rocephin?
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Name an adverse effect associated with high doses of Rocephin.
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What should be monitored during therapy with Rocephin?
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What should be done if symptoms of anaphylaxis occur?
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Study Notes
Rocephin Overview
- Rocephin is the brand name for the antibiotic ceftriaxone, a third-generation cephalosporin.
- It targets a wide range of infections caused by susceptible organisms.
Class and Indications
- Classified as an anti-infective medication.
- Effective in treating infections such as:
- Skin and skin structure infections
- Urinary and gynecologic infections
- Respiratory tract infections
- Meningitis and bone/joint infections
- Intra-abdominal infections and septicemia
- Otitis media
- Perioperative prophylaxis
- Lyme disease
Mechanism of Action
- Binds to the bacterial cell wall membrane, causing cell death.
- Exhibits bactericidal action, making it effective against susceptible bacteria.
Pharmacokinetics
- Ceftriaxone is partially metabolized and excreted via urine.
Side Effects
- Common side effects include:
- Headache
- Diarrhea, nausea, vomiting
- Abdominal cramps
- Rashes, urticaria
- Serious side effects may include:
- Agranulocytosis, bleeding complications.
- Hemolytic anemia, lymphocytosis, neutropenia, thrombocytopenia, thrombocytosis.
- Other effects: hematuria, vaginal moniliasis, pain at IM site, phlebitis at IV site.
Adverse Effects
- High doses can lead to seizures.
- Risk of pseudomembranous colitis.
- Possible reactions include:
- Anaphylaxis
- Serum sickness
- Stevens-Johnson syndrome
Nursing Implications
- Assess for signs of infection (vital signs, appearance of wounds, sputum, urine, stool, WBC count).
- Obtain patient history regarding previous reactions to penicillins or cephalosporins.
- Cultures should be taken before starting therapy; the first dose may be administered without results.
- Monitor for anaphylactic reactions; have emergency equipment ready.
- Observe bowel function and report significant changes.
- Check for rash frequently and discontinue if present, as it may indicate severe reactions.
- Special attention to pediatrics: assess newborns for jaundice before using ceftriaxone.
- Be aware that high doses may yield false positives on Coombs' tests.
Patient Education
- Instruct patients to complete the prescribed course to prevent resistance.
- Advise about the dangers of sharing medication.
- Warn against concurrent use of alcohol; may cause disulfiram-like reactions.
- Report any signs of superinfection or severe gastrointestinal symptoms promptly.
- Discuss use of calibrated measuring devices for liquid preparations in pediatric patients.
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Description
Boost your knowledge of Rocephin, a third-generation cephalosporin, with these flashcards. Learn important terms like its generic name and class/indications. Ideal for students in pharmacology or nursing.
