ROA: Oral, Injectable Pharm Action and Uses Quiz
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Questions and Answers

Which of the following is a potential consequence of abruptly withdrawing from treatment with Nadolol, according to the text?

  • Improved heart rate variability
  • Increased risk of cardiac ischemia (correct)
  • Decreased blood pressure
  • Enhanced effectiveness in treating hypertension

    • What condition is considered a contraindication for any drug that blocks Beta1 receptors?

  • Pre-existing Bradycardia (correct)
  • Respiratory disorder
  • Hypotension
  • Hyperlipidemia

    • Which type of beta blocker should be used for a patient with renal disease, based on the information provided?

  • Labetalol
  • Propranolol
  • Atenolol
  • Metoprolol (correct)

    • What is the Black Box Warning associated with abrupt withdrawal from Propranolol?

    <p>Increased risk of angina</p> Signup and view all the answers

    What knowledge is tested when questions refer to the 1st generation H1 antihistamines, according to the content?

    <p>Understanding about antihistamine drugs</p> Signup and view all the answers

    Which of the following is a key warning associated with the use of GCC agonist drugs like plecanatide and linaclotide?

    <p>Increased risk of dehydration in children</p> Signup and view all the answers

    Which of these drug classes is MOST likely to have a negative interaction with the somatostatin analogs like octreotide?

    <p>Antidiarrheals</p> Signup and view all the answers

    A patient is prescribed a GCC agonist drug like plecanatide or linaclotide. Which of the following medications should be avoided due to the risk of a negative interaction?

    <p>Muscarinic antagonists</p> Signup and view all the answers

    A patient with a history of chronic constipation is prescribed a GCC agonist drug. Which of the following adverse effects is MOST likely to occur?

    <p>Acute and severe diarrhea</p> Signup and view all the answers

    A patient is prescribed a somatostatin analog like octreotide for the treatment of diarrhea associated with a gastric neuroendocrine tumor. Which of the following is a potential drug-food interaction that should be considered?

    <p>Increased absorption with high-fat meals</p> Signup and view all the answers

    What is the primary mechanism of action of Mirabegron?

    <p>Relaxing the bladder to promote urinary retention</p> Signup and view all the answers

    Which of the following beta blockers has the potential for the most significant drug interactions?

    <p>Propranolol (non-selective)</p> Signup and view all the answers

    Which of the following beta blockers is NOT included on the Beers List of potentially inappropriate medications for use in the elderly?

    <p>Mirabegron (beta-3 agonist)</p> Signup and view all the answers

    Which of the following beta blockers has the potential for the least amount of adverse cardiovascular effects?

    <p>Timolol (ophthalmic)</p> Signup and view all the answers

    Which of the following drugs is most likely to cause urinary retention as an adverse effect?

    <p>Mirabegron (beta-3 agonist)</p> Signup and view all the answers

    Which drug class is associated with a black box warning due to significant cardiovascular and central nervous system depression in the elderly?

    <p>Systemic Alpha2 Agonists</p> Signup and view all the answers

    Which drug class promotes localized vasoconstriction of subcutaneous blood vessels when used topically for facial erythema (Rosacea)?

    <p>Topical Alpha2 Agonists</p> Signup and view all the answers

    Which pharmacologic class includes drugs that reduce sympathetic outflow and blood pressure but have contraindications in pre-existing cardiovascular disease?

    <p>Systemic Alpha2 Agonists</p> Signup and view all the answers

    Which drug class acts as competitive Alpha1-Adrenergic Antagonists promoting smooth muscle relaxation by blocking actions of norepinephrine?

    <p>Non-Selective Alpha1 Blockers</p> Signup and view all the answers

    Which drug class is specifically associated with Beers List due to its significant cardiovascular and central nervous system depression potential in the elderly?

    <p>Systemic Alpha2 Agonists</p> Signup and view all the answers

    Which of the following drugs has a black box warning for supine hypertension?

    <p>Droxidopa</p> Signup and view all the answers

    What is the mechanism of action of mecamylamine?

    <p>Ganglionic nicotinic blocker</p> Signup and view all the answers

    Which drug class is contraindicated in patients with pheochromocytoma?

    <p>Beta blockers</p> Signup and view all the answers

    What is the black box warning associated with norepinephrine?

    <p>Extravasation leading to ischemia and necrosis</p> Signup and view all the answers

    Which of the following drugs is used to treat hypotension?

    <p>Droxidopa</p> Signup and view all the answers

    What is the mechanism of action of methyldopa?

    <p>Metabolized to an alpha-2 agonist</p> Signup and view all the answers

    Which drug class is used for smoking cessation?

    <p>Nicotinic agonists</p> Signup and view all the answers

    What is the therapeutic class of varenicline?

    <p>Partial nicotinic agonist</p> Signup and view all the answers

    Which of the following routes of administration is NOT mentioned for nicotine products?

    <p>Oral tablets</p> Signup and view all the answers

    What is the mechanism of action of tyrosine hydroxylase inhibitors?

    <p>Reduce catecholamine synthesis</p> Signup and view all the answers

    Which of the following is a black box warning associated with first-generation H1 antihistamines?

    <p>Risk of sedation and impaired cognitive function</p> Signup and view all the answers

    Which of the following is a contraindication for the use of non-selective beta-blockers?

    <p>Asthma or chronic obstructive pulmonary disease (COPD)</p> Signup and view all the answers

    Which of the following is a black box warning associated with the use of beta-blockers in patients with heart failure?

    <p>Risk of worsening heart failure</p> Signup and view all the answers

    Which of the following is a contraindication for the use of first-generation H1 antihistamines in patients with angle-closure glaucoma?

    <p>Risk of exacerbating glaucoma due to mydriatic effects</p> Signup and view all the answers

    Which of the following is a black box warning associated with the use of non-selective beta-blockers in patients with diabetes mellitus?

    <p>Risk of masking symptoms of hypoglycemia</p> Signup and view all the answers

    Which of the following is a black box warning associated with the use of non-selective beta-blockers in patients with bronchospastic disease?

    <p>Risk of exacerbating bronchospasm</p> Signup and view all the answers

    Which of the following is a contraindication for the use of first-generation H1 antihistamines in elderly patients?

    <p>Significant anticholinergic effects</p> Signup and view all the answers

    What is the primary reason for the inclusion of non-selective beta-blockers on the Beers List of potentially inappropriate medications for the elderly?

    <p>Significant cardiovascular and central nervous system depression</p> Signup and view all the answers

    Which of the following is a contraindication for the use of non-selective beta-blockers in patients with peripheral vascular disease?

    <p>Risk of exacerbating claudication</p> Signup and view all the answers

    Which of the following is a black box warning associated with the use of first-generation H1 antihistamines in patients with angle-closure glaucoma?

    <p>Risk of exacerbating glaucoma symptoms</p> Signup and view all the answers

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