ROA: Oral, Injectable Pharm Action and Uses Quiz
40 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which of the following is a potential consequence of abruptly withdrawing from treatment with Nadolol, according to the text?

  • Improved heart rate variability
  • Increased risk of cardiac ischemia (correct)
  • Decreased blood pressure
  • Enhanced effectiveness in treating hypertension

What condition is considered a contraindication for any drug that blocks Beta1 receptors?

  • Pre-existing Bradycardia (correct)
  • Respiratory disorder
  • Hypotension
  • Hyperlipidemia

Which type of beta blocker should be used for a patient with renal disease, based on the information provided?

  • Labetalol
  • Propranolol
  • Atenolol
  • Metoprolol (correct)

What is the Black Box Warning associated with abrupt withdrawal from Propranolol?

<p>Increased risk of angina (D)</p> Signup and view all the answers

What knowledge is tested when questions refer to the 1st generation H1 antihistamines, according to the content?

<p>Understanding about antihistamine drugs (A)</p> Signup and view all the answers

Which of the following is a key warning associated with the use of GCC agonist drugs like plecanatide and linaclotide?

<p>Increased risk of dehydration in children (A)</p> Signup and view all the answers

Which of these drug classes is MOST likely to have a negative interaction with the somatostatin analogs like octreotide?

<p>Antidiarrheals (B)</p> Signup and view all the answers

A patient is prescribed a GCC agonist drug like plecanatide or linaclotide. Which of the following medications should be avoided due to the risk of a negative interaction?

<p>Muscarinic antagonists (C)</p> Signup and view all the answers

A patient with a history of chronic constipation is prescribed a GCC agonist drug. Which of the following adverse effects is MOST likely to occur?

<p>Acute and severe diarrhea (D)</p> Signup and view all the answers

A patient is prescribed a somatostatin analog like octreotide for the treatment of diarrhea associated with a gastric neuroendocrine tumor. Which of the following is a potential drug-food interaction that should be considered?

<p>Increased absorption with high-fat meals (A)</p> Signup and view all the answers

What is the primary mechanism of action of Mirabegron?

<p>Relaxing the bladder to promote urinary retention (C)</p> Signup and view all the answers

Which of the following beta blockers has the potential for the most significant drug interactions?

<p>Propranolol (non-selective) (A)</p> Signup and view all the answers

Which of the following beta blockers is NOT included on the Beers List of potentially inappropriate medications for use in the elderly?

<p>Mirabegron (beta-3 agonist) (B)</p> Signup and view all the answers

Which of the following beta blockers has the potential for the least amount of adverse cardiovascular effects?

<p>Timolol (ophthalmic) (C)</p> Signup and view all the answers

Which of the following drugs is most likely to cause urinary retention as an adverse effect?

<p>Mirabegron (beta-3 agonist) (C)</p> Signup and view all the answers

Which drug class is associated with a black box warning due to significant cardiovascular and central nervous system depression in the elderly?

<p>Systemic Alpha2 Agonists (B)</p> Signup and view all the answers

Which drug class promotes localized vasoconstriction of subcutaneous blood vessels when used topically for facial erythema (Rosacea)?

<p>Topical Alpha2 Agonists (D)</p> Signup and view all the answers

Which pharmacologic class includes drugs that reduce sympathetic outflow and blood pressure but have contraindications in pre-existing cardiovascular disease?

<p>Systemic Alpha2 Agonists (C)</p> Signup and view all the answers

Which drug class acts as competitive Alpha1-Adrenergic Antagonists promoting smooth muscle relaxation by blocking actions of norepinephrine?

<p>Non-Selective Alpha1 Blockers (D)</p> Signup and view all the answers

Which drug class is specifically associated with Beers List due to its significant cardiovascular and central nervous system depression potential in the elderly?

<p>Systemic Alpha2 Agonists (C)</p> Signup and view all the answers

Which of the following drugs has a black box warning for supine hypertension?

<p>Droxidopa (D)</p> Signup and view all the answers

What is the mechanism of action of mecamylamine?

<p>Ganglionic nicotinic blocker (A)</p> Signup and view all the answers

Which drug class is contraindicated in patients with pheochromocytoma?

<p>Beta blockers (A)</p> Signup and view all the answers

What is the black box warning associated with norepinephrine?

<p>Extravasation leading to ischemia and necrosis (C)</p> Signup and view all the answers

Which of the following drugs is used to treat hypotension?

<p>Droxidopa (B)</p> Signup and view all the answers

What is the mechanism of action of methyldopa?

<p>Metabolized to an alpha-2 agonist (A)</p> Signup and view all the answers

Which drug class is used for smoking cessation?

<p>Nicotinic agonists (A)</p> Signup and view all the answers

What is the therapeutic class of varenicline?

<p>Partial nicotinic agonist (C)</p> Signup and view all the answers

Which of the following routes of administration is NOT mentioned for nicotine products?

<p>Oral tablets (C)</p> Signup and view all the answers

What is the mechanism of action of tyrosine hydroxylase inhibitors?

<p>Reduce catecholamine synthesis (C)</p> Signup and view all the answers

Which of the following is a black box warning associated with first-generation H1 antihistamines?

<p>Risk of sedation and impaired cognitive function (D)</p> Signup and view all the answers

Which of the following is a contraindication for the use of non-selective beta-blockers?

<p>Asthma or chronic obstructive pulmonary disease (COPD) (C)</p> Signup and view all the answers

Which of the following is a black box warning associated with the use of beta-blockers in patients with heart failure?

<p>Risk of worsening heart failure (B)</p> Signup and view all the answers

Which of the following is a contraindication for the use of first-generation H1 antihistamines in patients with angle-closure glaucoma?

<p>Risk of exacerbating glaucoma due to mydriatic effects (B)</p> Signup and view all the answers

Which of the following is a black box warning associated with the use of non-selective beta-blockers in patients with diabetes mellitus?

<p>Risk of masking symptoms of hypoglycemia (B)</p> Signup and view all the answers

Which of the following is a black box warning associated with the use of non-selective beta-blockers in patients with bronchospastic disease?

<p>Risk of exacerbating bronchospasm (B)</p> Signup and view all the answers

Which of the following is a contraindication for the use of first-generation H1 antihistamines in elderly patients?

<p>Significant anticholinergic effects (D)</p> Signup and view all the answers

What is the primary reason for the inclusion of non-selective beta-blockers on the Beers List of potentially inappropriate medications for the elderly?

<p>Significant cardiovascular and central nervous system depression (D)</p> Signup and view all the answers

Which of the following is a contraindication for the use of non-selective beta-blockers in patients with peripheral vascular disease?

<p>Risk of exacerbating claudication (C)</p> Signup and view all the answers

Which of the following is a black box warning associated with the use of first-generation H1 antihistamines in patients with angle-closure glaucoma?

<p>Risk of exacerbating glaucoma symptoms (A)</p> Signup and view all the answers

More Like This

Use Quizgecko on...
Browser
Browser