Pharmacology: Drug Action Mechanisms
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Questions and Answers

What is the maximum dosage of aspirin prescribed in 24 hours?

  • 3.6 gm (correct)
  • 4.5 gm
  • 4.0 gm
  • 3.2 gm
  • What is the effect of aspirin on uric acid in the blood?

  • No effect on concentration
  • Variable effect on concentration
  • Increase in concentration (correct)
  • Decrease in concentration
  • What is the primary use of aspirin in patients who have suffered a stroke?

  • As an anti-inflammatory
  • As an antiplatelet drug (correct)
  • As an anticoagulant
  • As an analgesic
  • What is the treatment for aspirin overdose?

    <p>Induce vomiting and administer activated charcoal</p> Signup and view all the answers

    What is the effect of aspirin on kidney function?

    <p>Increase in edema formation</p> Signup and view all the answers

    What is the dosage of aspirin for an adult?

    <p>325-500mg not more than 4 gm in 24 hours</p> Signup and view all the answers

    What is a rare disorder associated with aspirin intake in children?

    <p>Reye's Syndrome</p> Signup and view all the answers

    What is the effect of aspirin on carbohydrate metabolism?

    <p>Increase in glucose levels</p> Signup and view all the answers

    What is a potential consequence of prescribing aspirin to a child with a viral infection?

    <p>Reye's syndrome</p> Signup and view all the answers

    What is a critical phrase to include when prescribing medication for pain management in children?

    <p>As needed</p> Signup and view all the answers

    Which treatment should be administered within 12 hours in case of aspirin overdosage?

    <p>N-acetylcysteine</p> Signup and view all the answers

    What is a symptom of hepatic necrosis due to aspirin overdosage?

    <p>Liver damage</p> Signup and view all the answers

    Aspirin binds firmly to plasma proteins, which may displace which type of drugs?

    <p>Other drugs from the binding site</p> Signup and view all the answers

    A common adverse reaction to aspirin is allergenicity. What does this imply?

    <p>Allergic reactions</p> Signup and view all the answers

    What is a key step in the initial treatment of aspirin overdosage?

    <p>Gastric lavage</p> Signup and view all the answers

    Which of the following conditions is not directly associated with aspirin use?

    <p>Hypertension</p> Signup and view all the answers

    Which of the following describes a drug with no intrinsic activity but has an affinity to block the effect of another drug?

    <p>Antagonist</p> Signup and view all the answers

    What is the relationship between drug dosage and effect called when the effect does not increase regardless of further dosage increments?

    <p>Maximal Effect</p> Signup and view all the answers

    What type of drug reaction cannot be attributed to a drug allergy and presents differently in a minority of patients?

    <p>Drug Idiosyncrasy</p> Signup and view all the answers

    Which example represents an additive effect where the combined drug effect is an algebraic sum of their individual responses?

    <p>Ibuprofen and Paracetamol</p> Signup and view all the answers

    Which term is used for a drug that increases the potency of another drug without having a significant effect on its own?

    <p>Potentiation</p> Signup and view all the answers

    What type of adverse reaction is mediated by sensitized cells and can manifest after a day or more?

    <p>Delayed Drug Allergy</p> Signup and view all the answers

    Which type of drug interaction refers to a greater than additive effect when combining two drugs?

    <p>Synergism</p> Signup and view all the answers

    Which adverse reaction occurs immediately and is mediated by circulating antibodies?

    <p>Intermediate Drug Allergy</p> Signup and view all the answers

    To manage excessive bleeding in a patient taking warfarin, it is crucial to avoid drugs that exhibit what type of interaction?

    <p>Pharmacologic Antagonism</p> Signup and view all the answers

    Which term is defined as the amount of drug necessary to produce a maximal effect?

    <p>Potency</p> Signup and view all the answers

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