Pharmacology: Drug Action Mechanisms

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Questions and Answers

What is the maximum dosage of aspirin prescribed in 24 hours?

  • 3.6 gm (correct)
  • 4.5 gm
  • 4.0 gm
  • 3.2 gm

What is the effect of aspirin on uric acid in the blood?

  • No effect on concentration
  • Variable effect on concentration
  • Increase in concentration (correct)
  • Decrease in concentration

What is the primary use of aspirin in patients who have suffered a stroke?

  • As an anti-inflammatory
  • As an antiplatelet drug (correct)
  • As an anticoagulant
  • As an analgesic

What is the treatment for aspirin overdose?

<p>Induce vomiting and administer activated charcoal (B)</p> Signup and view all the answers

What is the effect of aspirin on kidney function?

<p>Increase in edema formation (C)</p> Signup and view all the answers

What is the dosage of aspirin for an adult?

<p>325-500mg not more than 4 gm in 24 hours (D)</p> Signup and view all the answers

What is a rare disorder associated with aspirin intake in children?

<p>Reye's Syndrome (D)</p> Signup and view all the answers

What is the effect of aspirin on carbohydrate metabolism?

<p>Increase in glucose levels (C)</p> Signup and view all the answers

What is a potential consequence of prescribing aspirin to a child with a viral infection?

<p>Reye's syndrome (A)</p> Signup and view all the answers

What is a critical phrase to include when prescribing medication for pain management in children?

<p>As needed (D)</p> Signup and view all the answers

Which treatment should be administered within 12 hours in case of aspirin overdosage?

<p>N-acetylcysteine (A)</p> Signup and view all the answers

What is a symptom of hepatic necrosis due to aspirin overdosage?

<p>Liver damage (C)</p> Signup and view all the answers

Aspirin binds firmly to plasma proteins, which may displace which type of drugs?

<p>Other drugs from the binding site (A)</p> Signup and view all the answers

A common adverse reaction to aspirin is allergenicity. What does this imply?

<p>Allergic reactions (D)</p> Signup and view all the answers

What is a key step in the initial treatment of aspirin overdosage?

<p>Gastric lavage (A)</p> Signup and view all the answers

Which of the following conditions is not directly associated with aspirin use?

<p>Hypertension (B)</p> Signup and view all the answers

Which of the following describes a drug with no intrinsic activity but has an affinity to block the effect of another drug?

<p>Antagonist (C)</p> Signup and view all the answers

What is the relationship between drug dosage and effect called when the effect does not increase regardless of further dosage increments?

<p>Maximal Effect (A)</p> Signup and view all the answers

What type of drug reaction cannot be attributed to a drug allergy and presents differently in a minority of patients?

<p>Drug Idiosyncrasy (D)</p> Signup and view all the answers

Which example represents an additive effect where the combined drug effect is an algebraic sum of their individual responses?

<p>Ibuprofen and Paracetamol (B)</p> Signup and view all the answers

Which term is used for a drug that increases the potency of another drug without having a significant effect on its own?

<p>Potentiation (B)</p> Signup and view all the answers

What type of adverse reaction is mediated by sensitized cells and can manifest after a day or more?

<p>Delayed Drug Allergy (B)</p> Signup and view all the answers

Which type of drug interaction refers to a greater than additive effect when combining two drugs?

<p>Synergism (D)</p> Signup and view all the answers

Which adverse reaction occurs immediately and is mediated by circulating antibodies?

<p>Intermediate Drug Allergy (C)</p> Signup and view all the answers

To manage excessive bleeding in a patient taking warfarin, it is crucial to avoid drugs that exhibit what type of interaction?

<p>Pharmacologic Antagonism (C)</p> Signup and view all the answers

Which term is defined as the amount of drug necessary to produce a maximal effect?

<p>Potency (C)</p> Signup and view all the answers

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