RNA Viruses in Virology

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Questions and Answers

What is the consequence of a productive infection in a host cell?

  • No viral replication
  • Cell death and disease signs (correct)
  • Stable host condition
  • Viral latency

In the context of ssDNA viruses, what does the flow of information typically involve?

  • Protein → mRNA → DNA
  • RNA → Protein
  • DNA → mRNA → Protein (correct)
  • DNA → Protein

What is the role of a double-stranded replicative form (RF) in ssDNA viruses?

  • Manufacture viral proteins
  • Promote cell survival
  • Destroy dsRNA in cells
  • Serve as a template for viral genome copies (correct)

Which type of animal viruses do not utilize dsRNA in any of their processes?

<p>Double-stranded RNA viruses (B)</p> Signup and view all the answers

What happens if the viral genome of a latent infection is reactivated?

<p>Productive infection results (B)</p> Signup and view all the answers

In ssDNA viruses, what needs to be manufactured first when the viral genome is the same base sequence as the mRNA?

<p>Complementary DNA strand (D)</p> Signup and view all the answers

For minus-strand DNA viruses, how is the viral genome used to produce mRNA?

<p>By converting it to RNA first (B)</p> Signup and view all the answers

What happens in a host cell if a double-stranded RNA virus infects it?

<p>Systems in the cell eliminate dsRNA (B)</p> Signup and view all the answers

What is the main difference between ssDNA plus-strand and minus-strand DNA viruses regarding mRNA production?

<p>Plus-strand viruses produce mRNA directly from their genome (C)</p> Signup and view all the answers

What is the key outcome of viral genome reactivation in a latent infection of neurons?

<p>Development of disease signs (C)</p> Signup and view all the answers

Flashcards

Productive Infection Consequence

Cell death and observable disease symptoms in the host.

ssDNA Virus Information Flow

DNA is transcribed into mRNA, which is then translated into proteins.

Role of ds Replicative Form (RF)

The RF serves as a template, allowing for the creation of multiple copies of the viral genome.

Viruses NOT using dsRNA

Viruses with a double-stranded RNA genome.

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Reactivation of Latent Infection

The viral genome begins to actively replicate, leading to a productive infection.

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ssDNA (+ strand) Initial Production

A complementary DNA strand needs to be synthesized to act as a template for mRNA production.

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Minus-Strand DNA to mRNA

It is first converted to RNA, which then serves as mRNA for protein synthesis.

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Host Cell Response to dsRNA Virus

The host cell initiates defense mechanisms to eliminate the viral dsRNA.

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ssDNA mRNA Production Difference

Plus-strand viruses can directly produce mRNA from their genome, while minus-strand viruses need a complementary strand first.

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Latent Infection Reactivation in Neurons

The reactivation of a viral genome in neurons leads to renewed viral replication and subsequent development of disease symptoms.

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