Enteroviruses and Picornavirus Family

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Questions and Answers

What is the meaning of 'enteric' in enteroviruses?

  • Cardiovascular
  • Nervous
  • Intestinal (correct)
  • Respiratory

Which virus was historically the most significant disease caused by an enterovirus?

  • Echovirus
  • Poliovirus (correct)
  • Enterovirus D68
  • Coxsackie A virus

How many non-polio enteroviruses can cause disease in humans?

  • 81 (correct)
  • 22
  • 3
  • 25

What defines cellular receptor specificity and virus antigenicity of enteroviruses?

<p>Capsid proteins (B)</p> Signup and view all the answers

Based on their pathogenesis, how were the enteroviruses originally classified?

<p>Polioviruses, Coxsackie A viruses, Coxsackie B viruses, and echoviruses (D)</p> Signup and view all the answers

Which region is used to name enteroviruses isolated more recently?

<p>VP1 capsid region (B)</p> Signup and view all the answers

What do enteroviruses affect besides the intestine?

<p>Respiratory secretions and stool (D)</p> Signup and view all the answers

What is the transmission route for enteroviruses?

<p>'Enteric' transmission through the intestine (C)</p> Signup and view all the answers

How many serotypes of poliovirus exist?

<p>3 (C)</p> Signup and view all the answers

What is the characteristic genomic feature of enteroviruses?

<p>Single positive-strand genomic RNA (C)</p> Signup and view all the answers

Which of the following is not a classification group of enteroviruses based on pathogenesis?

<p>EV-D68, EV-B69, EV-D70, EV-A71 etc. (D)</p> Signup and view all the answers

What is the most common form of poliovirus encountered in nature?

<p>PV-1 (D)</p> Signup and view all the answers

Which type of enterovirus can affect the spinal cord and cause poliomyelitis?

<p>Poliovirus (D)</p> Signup and view all the answers

What defines the cellular receptor specificity and virus antigenicity of poliovirus?

<p>Capsid proteins (C)</p> Signup and view all the answers

What is the main method for diagnosing poliovirus infection?

<p>PCR (B)</p> Signup and view all the answers

What type of treatment is available for poliovirus infection?

<p>Supportive treatment (D)</p> Signup and view all the answers

Which form of poliovirus is the most common in nature?

<p>PV-1 (D)</p> Signup and view all the answers

What is the main method for diagnosing poliovirus infection?

<p>PCR (B)</p> Signup and view all the answers

Which form of poliovirus is the most common in nature?

<p>PV-1 (C)</p> Signup and view all the answers

What type of treatment is available for poliovirus infection?

<p>Supportive treatment (B)</p> Signup and view all the answers

Flashcards

Enterovirus definition

Enteroviruses are viruses that primarily infect the intestines.

Enterovirus transmission

Enteroviruses are transmitted through the intestine.

Poliovirus serotypes

There are 3 types of poliovirus.

Poliovirus pathogenicity

Poliovirus can affect the spinal cord and potentially cause poliomyelitis.

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Poliovirus diagnosis

Poliovirus infection is typically diagnosed using PCR.

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Poliovirus treatment

Poliovirus infection is treated with supportive care, there's no cure.

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Enterovirus classification

Historically categorized by pathogenesis into polioviruses, Coxsackie A, Coxsackie B, and echoviruses among others.

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Enterovirus genomic structure

Enteroviruses have a single positive-strand genomic RNA.

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Enterovirus receptor specificity

Capsid proteins determine how enteroviruses bind to cells.

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Historical significant enterovirus

Poliovirus used to be the leading viral disease caused by enteroviruses in many parts of the world.

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Non-polio enteroviruses

There are 81 types of non-polio enteroviruses known to cause disease.

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Most common poliovirus

PV-1 (Poliovirus type 1) is the most prevalent form in nature.

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Enterovirus affect (beyond intestine)

Besides the intestine, enteroviruses can affect respiratory secretions and stool.

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Enterovirus classification recent

More recent enteroviruses are named based on their VP1 capsid region.

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