36 Questions
Which virus is known to cause Koplik spots in the oral mucosa before the onset of the classic rash?
Rubella virus
What is a rare but severe complication of mumps involving inflammation of the brain and spinal cord?
Encephalitis
Which of the following is NOT a typical clinical manifestation of measles?
Blister-like skin lesions
In mumps infections, what is a rare outcome that can involve inflammation of the testicles in males or ovaries in females?
Orchitis
What distinguishes the rash seen in measles infections from other viral rashes?
Target-like appearance with concentric rings
What is the most feared negative outcome of measles infection on the central nervous system?
Subacute sclerosing panencephalitis (SSPE)
What are the characteristic lesions that appear before the rash in a patient with measles?
Koplik spots
Which of the following glands commonly swell in cases of mumps?
Parotid gland
What is a rare but serious complication of mumps that may cause sterility in males?
Orchitis
In measles, when does the characteristic rash typically appear?
After the appearance of Koplik spots
Which of the following is a potential severe complication of measles involving inflammation of the brain?
Encephalitis
What term is used to describe the most contagious phase of measles, characterized by fever and respiratory symptoms?
'Prodromal phase'
Which clinical feature distinguishes mumps from other viral infections like influenza or rhinovirus?
'Parotid swelling'
'Encephalitis' is a known complication associated with which viral infection?
'Measles virus'
Which severe neurological condition is a long-term complication sometimes associated with measles infection?
Subacute sclerosing panencephalitis (SSPE)
Which virus is known to cause severe acute respiratory syndrome?
Respiratory Syncytia virus
What is the primary mode of transmission for Coronaviruses?
Respiratory droplets
Which virus is associated with Guillain-Barré syndrome?
Influenza virus
What is the mechanism by which Respiratory Syncytia virus binds to host cells?
Glycoprotein binding to integrins
Which viral infection can lead to hydrophobia as a clinical manifestation?
Rabies virus
Which virus primarily targets the respiratory epithelium for replication?
Respiratory Syncytia virus
Which viral infection is associated with myocarditis as a potential complication?
Influenza virus
Which of the viruses listed is known to cause vesicular lesions on the skin?
Enteroviruses
What is the key cellular receptor targeted by Hantavirus for cell entry?
Nucleolin receptor
Which of the following viruses is characterized by its ability to cause congenital rubella syndrome in pregnant women?
Rubella virus
Which surface glycoprotein is important for viral binding of paramyxoviruses to the host cell?
Hemagglutinin (H)
In paramyxoviruses, which activity is required for cleaving sialic acid on viral or cellular glycoproteins to prevent self-binding and binding to infected cells?
Neuraminidase (N)
What is the primary method of transmission of paramyxoviruses among individuals?
Inhalation of large droplet aerosols
Which immune cells play a significant role in the immune-mediated cell injury resulting from respiratory syncytial virus (RSV) infections?
Neutrophils
What is the most common cause of fatal acute respiratory tract infection in infants and young children?
Respiratory syncytial virus (RSV)
Which Paramyxovirus binds to sialic acid on epithelial cells of the upper respiratory tract before moving to the parotid gland?
Paramyxovirus
Which clinical manifestation is a hallmark of mumps infections?
Parotitis
What role does the HN protein play in mumps virus infection?
Enables attachment to sialic acid on epithelial cells
Which condition may result from mumps virus infection and cause inflammation of the brain and spinal cord?
Encephalitis
What diagnostic method is used to detect antigens in urinary sediment or blood samples for measles diagnosis?
Immunofluorescence
What treatment option is available for measles cases involving administration of high-dose vitamin A as recommended by the World Health Organization?
High-dose vitamin A
Test your knowledge on the classification of RNA viruses based on families, genera, genome types, and envelope characteristics. Identify viruses like Measles, Mumps, Influenza, Hantavirus, Rabies, Coronavirus, and Enterovirus based on their classification attributes.
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