Podcast
Questions and Answers
What is the function of the long C-terminal tail of RNA polymerase II in eukaryotic mRNA processing?
What is the function of the long C-terminal tail of RNA polymerase II in eukaryotic mRNA processing?
- Cleaves the pre-mRNA to form mature mRNA.
- Directly transfers capping and splicing components to the emerging RNA. (correct)
- Coordinates with ribosomes for translation initiation.
- Binds to the consensus sequence AAUAAA.
Which protein binds to the hexamer AAUAAA in eukaryotic mRNA processing?
Which protein binds to the hexamer AAUAAA in eukaryotic mRNA processing?
- RNA polymerase II
- Poly-A polymerase
- CPSF (correct)
- CstF
In eukaryotic mRNA processing, what is the role of the CA sequence?
In eukaryotic mRNA processing, what is the role of the CA sequence?
- Promotes splicing of exons.
- Facilitates transcription initiation.
- Binds to the hexamer AAUAAA.
- Required for the cleavage step. (correct)
What happens when a mutation leaves a normal splice site without a partner in eukaryotic mRNA processing?
What happens when a mutation leaves a normal splice site without a partner in eukaryotic mRNA processing?
Which process ensures that the 3’ end of the pre-mRNA is appropriately processed by RNA polymerase II?
Which process ensures that the 3’ end of the pre-mRNA is appropriately processed by RNA polymerase II?
What happens when RNA polymerase II terminates transcription at the end of a gene?
What happens when RNA polymerase II terminates transcription at the end of a gene?
What is the role of the RNA polymerase tail in RNA splicing?
What is the role of the RNA polymerase tail in RNA splicing?
Which enzyme is responsible for adding a modified guanine nucleotide at the 5’ end of a new RNA molecule?
Which enzyme is responsible for adding a modified guanine nucleotide at the 5’ end of a new RNA molecule?
In eukaryotic mRNA processing, what is the function of a methyl transferase enzyme?
In eukaryotic mRNA processing, what is the function of a methyl transferase enzyme?
What happens once RNA polymerase II has produced about 25 nucleotides of RNA?
What happens once RNA polymerase II has produced about 25 nucleotides of RNA?
Which proteins seem to 'hop' from the polymerase tail onto the nascent RNA molecule for processing?
Which proteins seem to 'hop' from the polymerase tail onto the nascent RNA molecule for processing?
What can RNA polymerase II in elongation mode be viewed as?
What can RNA polymerase II in elongation mode be viewed as?
What modifications are made to the ends of eukaryotic mRNA?
What modifications are made to the ends of eukaryotic mRNA?
What is responsible for removing intron sequences from eukaryotic RNA transcripts?
What is responsible for removing intron sequences from eukaryotic RNA transcripts?
What is added to the RNA before transcription is completed?
What is added to the RNA before transcription is completed?
What type of sequences are present in eukaryotic mRNA resulting from transcription?
What type of sequences are present in eukaryotic mRNA resulting from transcription?
What is depicted as occurring concurrently in the RNA processing steps?
What is depicted as occurring concurrently in the RNA processing steps?
Which enzyme is responsible for adding the RNA cap to eukaryotic mRNA?
Which enzyme is responsible for adding the RNA cap to eukaryotic mRNA?
