Podcast
Questions and Answers
In the Cre-lox technique, what is the function of Cre-recombinase?
In the Cre-lox technique, what is the function of Cre-recombinase?
- It generates gene mutations in specific cells
- It binds to the loxP sequences flanking exon 2 and removes that exon (correct)
- It synthesizes albumin in the developing liver cells
- It activates the albumin gene promoter
What paracrine factors does the optic vesicle secrete to initiate lens formation?
What paracrine factors does the optic vesicle secrete to initiate lens formation?
- Sox and Pax6
- Nasal structures and Proteins
- BMP and FGF (correct)
- Morphogen and Iris
What is the promoter that activates the gene for Cre-recombinase in the Cre-lox technique?
What is the promoter that activates the gene for Cre-recombinase in the Cre-lox technique?
- Albumin gene promoter (correct)
- Hnf4α gene promoter
- Extracellular matrix (ECM) promoter
- Exon 2 promoter
What happens when Pax6 is lost in rats according to the text?
What happens when Pax6 is lost in rats according to the text?
How does paracrine signaling differ from juxtracrine signaling?
How does paracrine signaling differ from juxtracrine signaling?
In which cells does Pax6 play a role for proper lens induction according to the text?
In which cells does Pax6 play a role for proper lens induction according to the text?
What is the purpose of flanking the second exon with loxP sequences in the Cre-lox technique?
What is the purpose of flanking the second exon with loxP sequences in the Cre-lox technique?
What is a characteristic phenotype resulting from mutations in the Pax6 gene, as mentioned in the text?
What is a characteristic phenotype resulting from mutations in the Pax6 gene, as mentioned in the text?
What do cells exposed to intermediate concentrations of morphogen do?
What do cells exposed to intermediate concentrations of morphogen do?
What happens when Cre-recombinase binds to the loxP sequences flanking exon 2 in the Cre-lox technique?
What happens when Cre-recombinase binds to the loxP sequences flanking exon 2 in the Cre-lox technique?
Where is ribosomal protein Rpl38 concentrated in mice?
Where is ribosomal protein Rpl38 concentrated in mice?
What is the consequence of Rpl38 deficiency in mice?
What is the consequence of Rpl38 deficiency in mice?
What happens to futile cycle mutant embryos?
What happens to futile cycle mutant embryos?
Where are miRNAs processed by the Drosha RNAase in the cell?
Where are miRNAs processed by the Drosha RNAase in the cell?
What primarily makes up the RNA-induced silencing complex (RISC)?
What primarily makes up the RNA-induced silencing complex (RISC)?
