Ribavirin's Mutagenic Properties and Impact on Viral RNA Polymerase

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5 Questions

Which virus was used as a model in the study mentioned in the text?

Poliovirus

What effect does ribavirin have on infectious poliovirus production in cell culture?

Reduces it to 0.00001 percent

What is the relationship between the antiviral activity of ribavirin and its mutagenic activity?

They are directly related

What concept about nucleoside analogs does the study reveal?

Mutagenic ribonucleosides are important anti-RNA virus agents

Why do RNA viruses like HIV and influenza virus have a high mutation rate of their RNA polymerases with low fidelity for replication?

To avoid and escape most treatments and vaccines

Test your knowledge on the mutagenic properties of ribavirin and its impact on viral RNA polymerase. Take this quiz to learn more about the study published in Nature Medicine and its findings on reducing infectious poliovirus production.

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