Ribavirin's Mutagenic Properties and Impact on Viral RNA Polymerase
15 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Ribavirin incorporation is ______, because it serves as a template for incorporation of cytidine and uridine with equal efficiency

mutagenic

The antiviral activity of ribavirin correlates directly with its ______ activity

mutagenic

Ribavirin reduces infectious poliovirus production to as little as 0.00001 percent in ______ culture

cell

These data indicate that ribavirin forces the virus into ______ catastrophe

<p>error</p> Signup and view all the answers

RNA viruses like HIV and the influenza virus use a naturally high mutation rate of their RNA ______ with low fidelity for replication to avoid and escape most treatments and vaccines

<p>polymerases</p> Signup and view all the answers

True or false: Ribavirin incorporation is non-mutagenic?

<p>False</p> Signup and view all the answers

True or false: Ribavirin reduces infectious poliovirus production to as little as 0.00001 percent in cell culture?

<p>True</p> Signup and view all the answers

True or false: The antiviral activity of ribavirin correlates directly with its mutagenic activity?

<p>True</p> Signup and view all the answers

True or false: Ribavirin forces the virus into 'error catastrophe'?

<p>True</p> Signup and view all the answers

True or false: RNA viruses like HIV and the influenza virus have a naturally low mutation rate of their RNA polymerases for replication?

<p>False</p> Signup and view all the answers

True or false: Ribavirin is a mutagenic ribonucleoside?

<p>True</p> Signup and view all the answers

True or false: Ribavirin reduces infectious poliovirus production to as little as 0.00001 percent in cell culture?

<p>True</p> Signup and view all the answers

True or false: Ribavirin incorporation is non-mutagenic?

<p>False</p> Signup and view all the answers

True or false: RNA viruses like HIV and the influenza virus have a naturally low mutation rate of their RNA polymerases for replication?

<p>False</p> Signup and view all the answers

True or false: Ribavirin forces the virus into 'error catastrophe'?

<p>True</p> Signup and view all the answers

More Like This

Use Quizgecko on...
Browser
Browser