15 Questions
Ribavirin incorporation is ______, because it serves as a template for incorporation of cytidine and uridine with equal efficiency
mutagenic
The antiviral activity of ribavirin correlates directly with its ______ activity
mutagenic
Ribavirin reduces infectious poliovirus production to as little as 0.00001 percent in ______ culture
cell
These data indicate that ribavirin forces the virus into ______ catastrophe
error
RNA viruses like HIV and the influenza virus use a naturally high mutation rate of their RNA ______ with low fidelity for replication to avoid and escape most treatments and vaccines
polymerases
True or false: Ribavirin incorporation is non-mutagenic?
False
True or false: Ribavirin reduces infectious poliovirus production to as little as 0.00001 percent in cell culture?
True
True or false: The antiviral activity of ribavirin correlates directly with its mutagenic activity?
True
True or false: Ribavirin forces the virus into 'error catastrophe'?
True
True or false: RNA viruses like HIV and the influenza virus have a naturally low mutation rate of their RNA polymerases for replication?
False
True or false: Ribavirin is a mutagenic ribonucleoside?
True
True or false: Ribavirin reduces infectious poliovirus production to as little as 0.00001 percent in cell culture?
True
True or false: Ribavirin incorporation is non-mutagenic?
False
True or false: RNA viruses like HIV and the influenza virus have a naturally low mutation rate of their RNA polymerases for replication?
False
True or false: Ribavirin forces the virus into 'error catastrophe'?
True
Test your knowledge on the mutagenic properties of ribavirin and its impact on viral RNA polymerase. Take this quiz to learn more about the study published in Nature Medicine and its findings on reducing infectious poliovirus production.
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