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Questions and Answers
How is Rhinovirus typically transmitted?
How is Rhinovirus typically transmitted?
What is the optimal temperature for Rhinovirus growth?
What is the optimal temperature for Rhinovirus growth?
Why is it difficult to develop a vaccine against Rhinovirus?
Why is it difficult to develop a vaccine against Rhinovirus?
What is the primary mechanism by which Rhinovirus enters host cells?
What is the primary mechanism by which Rhinovirus enters host cells?
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What is the best way to prevent the spread of Rhinovirus?
What is the best way to prevent the spread of Rhinovirus?
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Study Notes
Rhinovirus Structure and Characteristics
- Rhinovirus is a positive sense single-stranded RNA virus.
- It is a small pico virus.
Transmission and Prevention
- Rhinovirus is transmitted via inhalation, as it is acid labile.
- It can also be transmitted through fomites, which highlights the importance of washing hands.
- Handwashing and disinfection of contaminated objects are the best means of preventing the spread of the virus.
Mechanism of Infection
- Rhinovirus attaches to ICAM-1 to enter host cells.
Optimal Environment
- Rhinovirus grows best in the upper respiratory tract at a temperature of around 33°C.
- It needs to be kept at a cool temperature to thrive.
Clinical Significance
- Rhinovirus is the most common cause of the common cold and upper respiratory tract infections.
- There are a ridiculous number of serotypes, with 113 total, which makes it challenging to develop a vaccine.
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