Rheumatoid Arthritis Treatment Recommendations
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Questions and Answers

What is the recommended frequency for monitoring in patients with active rheumatoid arthritis?

  • Every 2-4 months
  • Every 6-12 months
  • Every 3-6 months
  • Every 1-3 months (correct)
  • What should be considered if the treatment target is not achieved with the first conventional synthetic disease-modifying antirheumatic drug (csDMARD) strategy?

  • Add a biological DMARD (bDMARD) without further evaluation
  • Continue with the same csDMARD at a higher dose
  • Add a JAK-inhibitor immediately
  • Switch to a different csDMARD without considering poor prognostic factors (correct)
  • What is the first-line treatment if a patient has a contraindication to methotrexate?

  • Leflunomide (correct)
  • Hydroxychloroquine
  • Anakinra
  • Tocilizumab
  • When should short-term glucocorticoids be tapered and discontinued in the treatment of rheumatoid arthritis?

    <p>As rapidly as clinically feasible</p> Signup and view all the answers

    What is the recommended course of action if a biological disease-modifying antirheumatic drug (bDMARD) has failed in a patient?

    <p>Switch to another bDMARD</p> Signup and view all the answers

    In patients who cannot use conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) as comedication, what may be advantageous compared to other bDMARDs?

    <p>IL-6 pathway inhibitors</p> Signup and view all the answers

    What should be considered after glucocorticoids have been discontinued and a patient is in sustained remission?

    <p>Dose reduction of DMARDs</p> Signup and view all the answers

    What should be considered when the treatment target is not achieved with the first csDMARD strategy and poor prognostic factors are present?

    <p>Considering a bDMARD while taking pertinent risk factors into account</p> Signup and view all the answers

    What is the recommended action if there is no improvement in disease activity within 3 months of starting treatment for rheumatoid arthritis?

    <p>Adjust therapy as necessary</p> Signup and view all the answers

    In patients with a contraindication to methotrexate, what alternative therapy may be considered?

    <p>Leflunomide or sulfasalazine</p> Signup and view all the answers

    When should short-term glucocorticoids be tapered and discontinued in the treatment of rheumatoid arthritis?

    <p>Gradually and as rapidly as clinically feasible</p> Signup and view all the answers

    What is part of the first treatment strategy for rheumatoid arthritis according to recommendations?

    <p>(csDMARDs) Conventional Synthetic Disease-Modifying Antirheumatic Drugs</p> Signup and view all the answers

    In patients who cannot use conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) as comedication, what is mentioned as having potential advantages over other biological disease-modifying antirheumatic drugs?

    <p>IL-6 pathway inhibitors</p> Signup and view all the answers

    After glucocorticoids have been discontinued and a patient is in sustained remission, what can be considered for dose reduction according to the text?

    <p>Glucocorticoids and/or DMARDs</p> Signup and view all the answers

    What is recommended if a biological disease-modifying antirheumatic drug (bDMARD) or a targeted synthetic disease-modifying antirheumatic drug (tsDMARD) has failed according to the text?

    <p>Consider adding a conventional synthetic disease-modifying antirheumatic drug</p> Signup and view all the answers

    If a patient has failed treatment with one TNF inhibitor, what is recommended in terms of subsequent treatment according to the text?

    <p>Use another TNF inhibitor from a different class</p> Signup and view all the answers

    When considering treatment options after treatment failure with IL-6 receptor inhibitor therapy, what is recommended according to the text?

    <p>Consider switching to a TNF inhibitor</p> Signup and view all the answers

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