Rheumatoid Arthritis Treatment Recommendations

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17 Questions

What is the recommended frequency for monitoring in patients with active rheumatoid arthritis?

Every 1-3 months

What should be considered if the treatment target is not achieved with the first conventional synthetic disease-modifying antirheumatic drug (csDMARD) strategy?

Switch to a different csDMARD without considering poor prognostic factors

What is the first-line treatment if a patient has a contraindication to methotrexate?

Leflunomide

When should short-term glucocorticoids be tapered and discontinued in the treatment of rheumatoid arthritis?

As rapidly as clinically feasible

What is the recommended course of action if a biological disease-modifying antirheumatic drug (bDMARD) has failed in a patient?

Switch to another bDMARD

In patients who cannot use conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) as comedication, what may be advantageous compared to other bDMARDs?

IL-6 pathway inhibitors

What should be considered after glucocorticoids have been discontinued and a patient is in sustained remission?

Dose reduction of DMARDs

What should be considered when the treatment target is not achieved with the first csDMARD strategy and poor prognostic factors are present?

Considering a bDMARD while taking pertinent risk factors into account

What is the recommended action if there is no improvement in disease activity within 3 months of starting treatment for rheumatoid arthritis?

Adjust therapy as necessary

In patients with a contraindication to methotrexate, what alternative therapy may be considered?

Leflunomide or sulfasalazine

When should short-term glucocorticoids be tapered and discontinued in the treatment of rheumatoid arthritis?

Gradually and as rapidly as clinically feasible

What is part of the first treatment strategy for rheumatoid arthritis according to recommendations?

(csDMARDs) Conventional Synthetic Disease-Modifying Antirheumatic Drugs

In patients who cannot use conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) as comedication, what is mentioned as having potential advantages over other biological disease-modifying antirheumatic drugs?

IL-6 pathway inhibitors

After glucocorticoids have been discontinued and a patient is in sustained remission, what can be considered for dose reduction according to the text?

Glucocorticoids and/or DMARDs

What is recommended if a biological disease-modifying antirheumatic drug (bDMARD) or a targeted synthetic disease-modifying antirheumatic drug (tsDMARD) has failed according to the text?

Consider adding a conventional synthetic disease-modifying antirheumatic drug

If a patient has failed treatment with one TNF inhibitor, what is recommended in terms of subsequent treatment according to the text?

Use another TNF inhibitor from a different class

When considering treatment options after treatment failure with IL-6 receptor inhibitor therapy, what is recommended according to the text?

Consider switching to a TNF inhibitor

Test your knowledge on the recommendations for treating Rheumatoid Arthritis, including the early use of DMARDs, aiming for remission, frequent monitoring, and the use of Methotrexate as part of the initial treatment. Prepare for exams or refresh your understanding of RA management guidelines.

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