Rh Factor Sensitization Quiz
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Questions and Answers

What type of antibodies are most agglutinins?

  • IgG
  • IgM (correct)
  • IgA
  • IgE
  • Which antigen system is considered the most important for causing transfusion reactions?

  • Rh factor system (correct)
  • Lutheran system
  • Kell system
  • ABO system
  • How are people with the Rh factor designated in terms of their blood?

  • Rh-positive (correct)
  • Rh-altered
  • Rh-negative
  • Rh-natural
  • What must happen for enough agglutinins to develop against the Rh factor?

    <p>Massive exposure to an Rh antigen</p> Signup and view all the answers

    How many common types of Rh antigens are there?

    <p>6</p> Signup and view all the answers

    Which is the most antigenic Rh antigen among the common types?

    <p>Type D</p> Signup and view all the answers

    How do naturally occurring antibodies differ between ABO and Rh systems?

    <p>No naturally occurring antibodies in ABO, but they occur in Rh system</p> Signup and view all the answers

    What is the significance of the A and B antigens on the surfaces of RBCs?

    <p>They cause RBC agglutination</p> Signup and view all the answers

    Which blood type is classified as type O?

    <p>When neither A nor B antigens are present</p> Signup and view all the answers

    Why is a person with a particular blood group unable to have antibodies of the same type in their plasma?

    <p>Due to the presence of antigens in their plasma</p> Signup and view all the answers

    What causes blood transfusion reactions in individuals?

    <p>The presence of blood group antibodies</p> Signup and view all the answers

    What are the two major antigen systems likely to cause blood transfusion reactions?

    <p>O-A-B system and Rh system</p> Signup and view all the answers

    When is blood type classified as type A?

    <p>When only the A antigen is present</p> Signup and view all the answers

    What happens when both A and B antigens are present on RBC surfaces?

    <p>The blood type is classified as AB</p> Signup and view all the answers

    What does it mean if a person has antibody against an antigen present on their own RBCs?

    <p>They will experience complications upon transfusion</p> Signup and view all the answers

    What happens when RBCs containing Rh factor are injected into an Rh-negative person?

    <p>Delayed transfusion reaction</p> Signup and view all the answers

    In which scenario does erythroblastosis fetalis occur?

    <p>When the mother is Rh-negative and the father is Rh-positive</p> Signup and view all the answers

    Why does an Rh-negative mother usually not harm her first Rh-positive child?

    <p>Due to the mother not developing enough anti-Rh agglutinins</p> Signup and view all the answers

    What causes agglutination and phagocytosis of the fetus's RBCs in erythroblastosis fetalis?

    <p>Presence of anti-Rh agglutinins in the mother</p> Signup and view all the answers

    What happens with multiple exposures to the Rh factor in an Rh-negative person?

    <p>Sensitivity to Rh factor increases</p> Signup and view all the answers

    Which parent carries the risk of developing anti-Rh agglutinins in erythroblastosis fetalis?

    <p>The mother</p> Signup and view all the answers

    What characterizes erythroblastosis fetalis?

    <p>Agglutination and phagocytosis of the fetus’s RBCs</p> Signup and view all the answers

    What is the outcome if an Rh-negative person has repeated exposure to the Rh factor?

    <p>Increased risk of immediate transfusion reaction</p> Signup and view all the answers

    What is the consequence of precipitation of bilirubin in neuronal cells?

    <p>All of the above</p> Signup and view all the answers

    What is the purpose of administering Rh immunoglobulin (anti-D antibody) to expectant mothers?

    <p>To prevent sensitization of the mother</p> Signup and view all the answers

    How does the anti-D antibody prevent the development of large amounts of D antibodies in the expectant mother?

    <p>By inhibiting antibody production</p> Signup and view all the answers

    What happens to fetal Rh-positive RBCs that come in contact with the administered anti-D antibody?

    <p>They have their D antigen sites occupied</p> Signup and view all the answers

    In treating erythroblastosis fetalis, what blood type is typically used for replacement of the neonate's blood?

    <p>Rh-negative blood</p> Signup and view all the answers

    When should administration of Rh immunoglobulin begin in expectant mothers?

    <p>At 28-30 weeks of gestation</p> Signup and view all the answers

    What is the primary goal of treating neonates with erythroblastosis fetalis?

    <p>To replace the neonate's blood with compatible blood</p> Signup and view all the answers

    How does administration of Rh immunoglobulin help in preventing sensitization of mothers to the D antigen?

    <p>By attaching to D antigen sites on fetal RBCs</p> Signup and view all the answers

    What is the primary function of the liver in relation to bilirubin?

    <p>Excreting bilirubin in the bile</p> Signup and view all the answers

    In what scenario does jaundice usually not appear in adults?

    <p>With normal liver function and excretion of bile pigment into the intestines</p> Signup and view all the answers

    What can cause kidney failure after transfusion reactions?

    <p>Loss of circulating RBCs in the recipient</p> Signup and view all the answers

    What is a major effect of renal vasoconstriction on kidney function?

    <p>Kidney shutdown</p> Signup and view all the answers

    How does circulatory shock contribute to kidney failure post-transfusion reactions?

    <p>By causing a decrease in urine output</p> Signup and view all the answers

    What happens when arterial blood pressure falls very low during acute renal failure?

    <p>Renal blood flow and urine output decrease</p> Signup and view all the answers

    Which factor contributes to the appearance of jaundice in a person?

    <p>Toxic substances released from hemolyzing blood</p> Signup and view all the answers

    What leads to powerful renal vasoconstriction during a transfusion reaction?

    <p>Antigen-antibody reactions releasing toxic substances</p> Signup and view all the answers

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