Podcast
Questions and Answers
What type of antibodies are most agglutinins?
What type of antibodies are most agglutinins?
- IgG
- IgM (correct)
- IgA
- IgE
Which antigen system is considered the most important for causing transfusion reactions?
Which antigen system is considered the most important for causing transfusion reactions?
- Rh factor system (correct)
- Lutheran system
- Kell system
- ABO system
How are people with the Rh factor designated in terms of their blood?
How are people with the Rh factor designated in terms of their blood?
- Rh-positive (correct)
- Rh-altered
- Rh-negative
- Rh-natural
What must happen for enough agglutinins to develop against the Rh factor?
What must happen for enough agglutinins to develop against the Rh factor?
How many common types of Rh antigens are there?
How many common types of Rh antigens are there?
Which is the most antigenic Rh antigen among the common types?
Which is the most antigenic Rh antigen among the common types?
How do naturally occurring antibodies differ between ABO and Rh systems?
How do naturally occurring antibodies differ between ABO and Rh systems?
What is the significance of the A and B antigens on the surfaces of RBCs?
What is the significance of the A and B antigens on the surfaces of RBCs?
Which blood type is classified as type O?
Which blood type is classified as type O?
Why is a person with a particular blood group unable to have antibodies of the same type in their plasma?
Why is a person with a particular blood group unable to have antibodies of the same type in their plasma?
What causes blood transfusion reactions in individuals?
What causes blood transfusion reactions in individuals?
What are the two major antigen systems likely to cause blood transfusion reactions?
What are the two major antigen systems likely to cause blood transfusion reactions?
When is blood type classified as type A?
When is blood type classified as type A?
What happens when both A and B antigens are present on RBC surfaces?
What happens when both A and B antigens are present on RBC surfaces?
What does it mean if a person has antibody against an antigen present on their own RBCs?
What does it mean if a person has antibody against an antigen present on their own RBCs?
What happens when RBCs containing Rh factor are injected into an Rh-negative person?
What happens when RBCs containing Rh factor are injected into an Rh-negative person?
In which scenario does erythroblastosis fetalis occur?
In which scenario does erythroblastosis fetalis occur?
Why does an Rh-negative mother usually not harm her first Rh-positive child?
Why does an Rh-negative mother usually not harm her first Rh-positive child?
What causes agglutination and phagocytosis of the fetus's RBCs in erythroblastosis fetalis?
What causes agglutination and phagocytosis of the fetus's RBCs in erythroblastosis fetalis?
What happens with multiple exposures to the Rh factor in an Rh-negative person?
What happens with multiple exposures to the Rh factor in an Rh-negative person?
Which parent carries the risk of developing anti-Rh agglutinins in erythroblastosis fetalis?
Which parent carries the risk of developing anti-Rh agglutinins in erythroblastosis fetalis?
What characterizes erythroblastosis fetalis?
What characterizes erythroblastosis fetalis?
What is the outcome if an Rh-negative person has repeated exposure to the Rh factor?
What is the outcome if an Rh-negative person has repeated exposure to the Rh factor?
What is the consequence of precipitation of bilirubin in neuronal cells?
What is the consequence of precipitation of bilirubin in neuronal cells?
What is the purpose of administering Rh immunoglobulin (anti-D antibody) to expectant mothers?
What is the purpose of administering Rh immunoglobulin (anti-D antibody) to expectant mothers?
How does the anti-D antibody prevent the development of large amounts of D antibodies in the expectant mother?
How does the anti-D antibody prevent the development of large amounts of D antibodies in the expectant mother?
What happens to fetal Rh-positive RBCs that come in contact with the administered anti-D antibody?
What happens to fetal Rh-positive RBCs that come in contact with the administered anti-D antibody?
In treating erythroblastosis fetalis, what blood type is typically used for replacement of the neonate's blood?
In treating erythroblastosis fetalis, what blood type is typically used for replacement of the neonate's blood?
When should administration of Rh immunoglobulin begin in expectant mothers?
When should administration of Rh immunoglobulin begin in expectant mothers?
What is the primary goal of treating neonates with erythroblastosis fetalis?
What is the primary goal of treating neonates with erythroblastosis fetalis?
How does administration of Rh immunoglobulin help in preventing sensitization of mothers to the D antigen?
How does administration of Rh immunoglobulin help in preventing sensitization of mothers to the D antigen?
What is the primary function of the liver in relation to bilirubin?
What is the primary function of the liver in relation to bilirubin?
In what scenario does jaundice usually not appear in adults?
In what scenario does jaundice usually not appear in adults?
What can cause kidney failure after transfusion reactions?
What can cause kidney failure after transfusion reactions?
What is a major effect of renal vasoconstriction on kidney function?
What is a major effect of renal vasoconstriction on kidney function?
How does circulatory shock contribute to kidney failure post-transfusion reactions?
How does circulatory shock contribute to kidney failure post-transfusion reactions?
What happens when arterial blood pressure falls very low during acute renal failure?
What happens when arterial blood pressure falls very low during acute renal failure?
Which factor contributes to the appearance of jaundice in a person?
Which factor contributes to the appearance of jaundice in a person?
What leads to powerful renal vasoconstriction during a transfusion reaction?
What leads to powerful renal vasoconstriction during a transfusion reaction?
