Podcast
Questions and Answers
What is the origin of v-src in Rous Sarcoma virus?
What is the origin of v-src in Rous Sarcoma virus?
- It originated from a viral gene
- It originated from a cellular counterpart c-src (correct)
- It was inserted by a retrovirus
- It was formed by a mutation in the LTR
How do cis-activating retroviruses contribute to cancer development?
How do cis-activating retroviruses contribute to cancer development?
- By inserting a promoter near an oncogene (correct)
- By inducing a mutation in the LTR
- By inserting an enhancer far from an oncogene
- By inactivating a tumor suppressor gene
What is the mechanism by which HTLV-1 causes adult T cell leukemia (ATL)?
What is the mechanism by which HTLV-1 causes adult T cell leukemia (ATL)?
- By integrating into a specific site in the host genome
- By inserting a promoter near an oncogene
- By inactivating a tumor suppressor gene
- By expressing viral oncogenic proteins TAX1/HBZ (correct)
What is the global distribution of HTLV-1?
What is the global distribution of HTLV-1?
How many subtypes of HTLV are there?
How many subtypes of HTLV are there?
What is the primary mode of transmission of HTLV-1?
What is the primary mode of transmission of HTLV-1?
What is the role of the Long Terminal Repeat (LTR) in retroviral integration?
What is the role of the Long Terminal Repeat (LTR) in retroviral integration?
What is the main difference between transducing and cis-activating retroviruses?
What is the main difference between transducing and cis-activating retroviruses?
Which of the following is NOT a characteristic of HTLV-1 infection?
Which of the following is NOT a characteristic of HTLV-1 infection?
What is the role of the Tax protein in HTLV-1 infection?
What is the role of the Tax protein in HTLV-1 infection?
What is the primary mechanism of cancer development associated with 'high risk' HPV infection?
What is the primary mechanism of cancer development associated with 'high risk' HPV infection?
What is the primary function of the reverse transcriptase enzyme in retroviruses?
What is the primary function of the reverse transcriptase enzyme in retroviruses?
What is the primary mechanism of HTLV transmission?
What is the primary mechanism of HTLV transmission?
What is the characteristic feature of Adult T cell Leukemia (ATL) cells?
What is the characteristic feature of Adult T cell Leukemia (ATL) cells?
What is the prognosis of Chronic ATL?
What is the prognosis of Chronic ATL?
What is the primary symptom of HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)?
What is the primary symptom of HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)?
What is the function of the Tax protein in the HTLV lifecycle?
What is the function of the Tax protein in the HTLV lifecycle?
What is the result of Tax1 transgenic mice?
What is the result of Tax1 transgenic mice?
What is the outcome of infection with low risk HPV genotypes?
What is the outcome of infection with low risk HPV genotypes?
Which of the following proteins is NOT associated with HPV?
Which of the following proteins is NOT associated with HPV?
What is the outcome of chronic infection with HTLV-1?
What is the outcome of chronic infection with HTLV-1?
What is the role of the E6 and E7 proteins in HPV infection?
What is the role of the E6 and E7 proteins in HPV infection?
What is the availability of a vaccine against HPV?
What is the availability of a vaccine against HPV?
What is the role of HBZ in HTLV-1 infection?
What is the role of HBZ in HTLV-1 infection?
Which of the following is a characteristic of Papillomaviruses?
Which of the following is a characteristic of Papillomaviruses?
What is the clinical manifestation of Low-Risk (LR) HPV genotypes in cutaneous infections?
What is the clinical manifestation of Low-Risk (LR) HPV genotypes in cutaneous infections?
How are High-Risk (HR) HPV genotypes transmitted?
How are High-Risk (HR) HPV genotypes transmitted?
What is the role of HPV 16, 18, 31, and 45 in cervical cancer?
What is the role of HPV 16, 18, 31, and 45 in cervical cancer?
What is the result of the integration of Oncogenic viral genes E6 and E7 into the host genome?
What is the result of the integration of Oncogenic viral genes E6 and E7 into the host genome?
What is the role of Anti-L1 antibodies in HPV infection?
What is the role of Anti-L1 antibodies in HPV infection?
What is the composition of the HPV vaccine Gardasil 9?
What is the composition of the HPV vaccine Gardasil 9?
What is the result of the immune response against HPV infection?
What is the result of the immune response against HPV infection?
What is the significance of Koilocytes in HPV infection?
What is the significance of Koilocytes in HPV infection?
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