Podcast
Questions and Answers
What is the typical resting membrane potential (RMP) value for a cell?
What is the typical resting membrane potential (RMP) value for a cell?
- -90 mV
- -70 mV (correct)
- -50 mV
- -30 mV
Which of the following factors primarily helps maintain the concentration gradients for sodium and potassium ions?
Which of the following factors primarily helps maintain the concentration gradients for sodium and potassium ions?
- Diffusion
- Electrostatic interactions
- Cellular respiration
- Ion transport (correct)
What is the function of the Na+/K+ pump in relation to resting membrane potential?
What is the function of the Na+/K+ pump in relation to resting membrane potential?
- It relies solely on passive diffusion for ion movement.
- It transports three sodium ions out for every two potassium ions in. (correct)
- It passively allows sodium and potassium to diffuse equally.
- It increases sodium concentration inside the cell.
Which ion has the most substantial effect on the resting membrane potential due to its higher permeability?
Which ion has the most substantial effect on the resting membrane potential due to its higher permeability?
The 'salty banana' analogy is used to describe the distribution of which ion across the cell membrane?
The 'salty banana' analogy is used to describe the distribution of which ion across the cell membrane?
What is the impact of negatively charged ions inside the cell on the resting membrane potential?
What is the impact of negatively charged ions inside the cell on the resting membrane potential?
What does the Goldman Katz Equation help predict?
What does the Goldman Katz Equation help predict?
What is the primary function of the cilia in olfactory receptor neurons?
What is the primary function of the cilia in olfactory receptor neurons?
How many distinct odors can humans distinguish using their olfactory receptor neurons?
How many distinct odors can humans distinguish using their olfactory receptor neurons?
What role does cyclic AMP (cAMP) play in olfactory signal transduction?
What role does cyclic AMP (cAMP) play in olfactory signal transduction?
What is the function of glomeruli in the olfactory bulb?
What is the function of glomeruli in the olfactory bulb?
What type of receptor are the odorant receptors classified as?
What type of receptor are the odorant receptors classified as?
What is the main pathway for retinal ganglion cells to transmit visual information to the brain?
What is the main pathway for retinal ganglion cells to transmit visual information to the brain?
Which structure is primarily responsible for converting light into neural signals?
Which structure is primarily responsible for converting light into neural signals?
What role does the lateral geniculate nucleus (LGN) play in the visual pathway?
What role does the lateral geniculate nucleus (LGN) play in the visual pathway?
Which part of the eye adjusts the size of the pupil based on light intensity?
Which part of the eye adjusts the size of the pupil based on light intensity?
What is the significance of visuotopic mapping in the striate cortex?
What is the significance of visuotopic mapping in the striate cortex?
What does 'plasticity' in the striate cortex refer to?
What does 'plasticity' in the striate cortex refer to?
In terms of light perception, what is the range of the visible spectrum?
In terms of light perception, what is the range of the visible spectrum?
Which component of the eye is responsible for initial light refraction?
Which component of the eye is responsible for initial light refraction?
How does the ciliary muscle contribute to vision?
How does the ciliary muscle contribute to vision?
What function does the aqueous humor serve in the eye?
What function does the aqueous humor serve in the eye?
What role does myelin play in action potential conduction?
What role does myelin play in action potential conduction?
What is the function of the nodes of Ranvier in saltatory conduction?
What is the function of the nodes of Ranvier in saltatory conduction?
What distinguishes electrical synapses from chemical synapses?
What distinguishes electrical synapses from chemical synapses?
Which type of synapse is more prevalent in the mammalian brain?
Which type of synapse is more prevalent in the mammalian brain?
What is a characteristic feature of gap junctions in electrical synapses?
What is a characteristic feature of gap junctions in electrical synapses?
What is the primary role of neurotransmitters in chemical synapses?
What is the primary role of neurotransmitters in chemical synapses?
What is a feature of reciprocal synapses?
What is a feature of reciprocal synapses?
What do presynaptic cells contain to facilitate neurotransmitter release?
What do presynaptic cells contain to facilitate neurotransmitter release?
What enhances the efficiency of presynaptic to postsynaptic communication in rectifying synapses?
What enhances the efficiency of presynaptic to postsynaptic communication in rectifying synapses?
What is the condition of monochromats regarding color perception?
What is the condition of monochromats regarding color perception?
How do rods function in the darkness?
How do rods function in the darkness?
What role does the Lateral Geniculate Nucleus (LGN) serve?
What role does the Lateral Geniculate Nucleus (LGN) serve?
Which of the following describes the function of the ventral stream?
Which of the following describes the function of the ventral stream?
What does visuotopic organization in the visual cortex refer to?
What does visuotopic organization in the visual cortex refer to?
What is the responsibility of retinal ganglion cells?
What is the responsibility of retinal ganglion cells?
Which aspect is true of the dorsal stream?
Which aspect is true of the dorsal stream?
In which condition do cones function primarily?
In which condition do cones function primarily?
What is the role of the iris in the eye?
What is the role of the iris in the eye?
Which of the following statements about binocular vision is correct?
Which of the following statements about binocular vision is correct?
Flashcards
What is Resting Membrane Potential (RMP)?
What is Resting Membrane Potential (RMP)?
The difference in electrical charge across the cell membrane when the cell is at rest, typically around -70 mV.
How does diffusion contribute to RMP?
How does diffusion contribute to RMP?
The passive movement of ions across the cell membrane, driven by differences in concentration.
What role do electrostatic interactions play in RMP?
What role do electrostatic interactions play in RMP?
The attractive or repulsive forces between charged particles, influencing their distribution and movement across the membrane.
How does the Na+/K+ pump contribute to RMP?
How does the Na+/K+ pump contribute to RMP?
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What is ion permeability and how does it affect RMP?
What is ion permeability and how does it affect RMP?
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What is the Goldman Katz Equation?
What is the Goldman Katz Equation?
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Explain the Salty Banana analogy for RMP.
Explain the Salty Banana analogy for RMP.
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Synapse
Synapse
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Chemical Synapse
Chemical Synapse
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Electrical Synapse
Electrical Synapse
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Gap Junctions
Gap Junctions
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Synaptic Vesicles
Synaptic Vesicles
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Presynaptic Neuron
Presynaptic Neuron
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Postsynaptic Neuron
Postsynaptic Neuron
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Reciprocal Synapses
Reciprocal Synapses
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Rectifying Synapses
Rectifying Synapses
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Olfactory Receptor Neuron
Olfactory Receptor Neuron
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Olfactory Signal Transduction
Olfactory Signal Transduction
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Odorants
Odorants
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Odorant Receptors
Odorant Receptors
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Glomerulus
Glomerulus
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Visible Spectrum
Visible Spectrum
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Iris
Iris
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Intensity (Light)
Intensity (Light)
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Optic Axis
Optic Axis
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Visual Axis
Visual Axis
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Cornea
Cornea
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Lens
Lens
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Retina
Retina
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Optic Nerve
Optic Nerve
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Sphincter Pupillae
Sphincter Pupillae
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Monochromat
Monochromat
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Light Impact on Rods
Light Impact on Rods
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Retinal Ganglion Cells
Retinal Ganglion Cells
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Lateral Geniculate Nucleus (LGN)
Lateral Geniculate Nucleus (LGN)
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Striate Cortex
Striate Cortex
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Visuotopic Organization
Visuotopic Organization
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Cells with Direction Selectivity
Cells with Direction Selectivity
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Ocular Dominance Columns
Ocular Dominance Columns
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Ventral Stream
Ventral Stream
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Dorsal Stream
Dorsal Stream
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Study Notes
Resting Membrane Potential (RMP)
- RMP is the difference in charged particle distribution across a cell membrane when not stimulated.
- Typically around -70 mV.
- Maintained by diffusion of ions, electrostatic interactions, and ion transport (Na+/K+ pump).
- The Na+/K+ pump actively transports 3 sodium ions out of the cell for every 2 potassium ions it brings in, contributing to the negative charge inside the cell.
- negatively charged ions and proteins inside the cell are also key.
- Salty banana analogy: intracellular Na+ concentration is lower than extracellular, while K+ concentration is higher inside the cell.
Ion Transport
- Facilitated mainly by the Na+/K+ pump.
- Crucial for maintaining concentration gradients.
- Requires energy (ATP) for its function.
Goldman Katz Equation
- Predicts the equilibrium potential for an ion across a membrane.
- Used to estimate the membrane potential if the membrane is permeable to multiple ions.
- Consider permeability ratios of different ions.
Permeability Ratios (at rest)
- Potassium (K+) : Chloride (Cl-) : Sodium (Na+) ≈ 1 : 0.45 : 0.04.
- K+ has the greatest impact on the resting membrane potential due to its higher membrane permeability.
Changes in Extracellular K+ Concentration
- Increase in extracellular K+ decreases the concentration gradient, resulting in depolarization (neuron closer to firing).
- Decrease in extracellular K+ increases the concentration gradient, leading to hyperpolarization (neuron further from firing).
Factors Influencing Membrane Potential
- Diffusion of ions, especially potassium, creates a net positive charge loss inside the cell.
- Active transport by the Na+/K+ ATPase pump causes a net loss of positive charge.
- Electrochemical gradients also impact K+ movement, influencing charge balance.
Action Potentials
- Initiated by changes in membrane voltage.
- Hyperpolarization—adding negative charges; depolarization—adding positive charges.
- Threshold: generally around -55 mV.
- Essential for communication between neurons.
Phases of Action Potential
- Resting: Stable membrane potential.
- Threshold: Graded potentials reach a critical level triggering the action potential.
- Depolarization: Influx of sodium ions increases membrane potential positively.
- Repolarization: Outflux of potassium ions returns membrane potential to negative.
- Refractory Period: Brief period where the neuron is less excitable following an action potential; absolute and relative refractory periods exist.
Refractory Periods
- Absolute Refractory Period: brief window where another action potential cannot be produced due to inactivation of Na+ channels.
- Relative Refractory Period: additional stimulus required to trigger another action potential due to hyperpolarization.
Voltage-Gated Channels
- Critical for action potential propagation (specifically Na+ and K+ channels).
- Na+ channels rapidly open during depolarization allowing Na+ influx and close slowly.
- K+ channels open later, increasing K+ permeability, and contribute to repolarization.
Action Potential Summary
- All-or-nothing events initiated at a threshold.
- They facilitate fast electrical signal transmission.
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Description
Explore the concept of Resting Membrane Potential (RMP) and its significance in cellular biology. This quiz delves into ion transport mechanisms, particularly the Na+/K+ pump, and introduces the Goldman Katz Equation for membrane potential calculations. Test your understanding of these fundamental physiological processes.