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Questions and Answers
What is the function of the fissure in the lung?
What is the function of the fissure in the lung?
What is the portion of the lung that contains alveoli and participates in gas exchange?
What is the portion of the lung that contains alveoli and participates in gas exchange?
What is the main function of type I alveolar cells?
What is the main function of type I alveolar cells?
What is the function of surfactant?
What is the function of surfactant?
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What is the structure that wraps around the lobule of the lung?
What is the structure that wraps around the lobule of the lung?
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What is the function of the nasopharynx in relation to the auditory tubes?
What is the function of the nasopharynx in relation to the auditory tubes?
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What is the name of the cells that secrete alveolar fluid, including surfactant?
What is the name of the cells that secrete alveolar fluid, including surfactant?
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How many lobes does the right lung have?
How many lobes does the right lung have?
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What type of epithelium lines the wall of the oropharynx?
What type of epithelium lines the wall of the oropharynx?
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What is the name of the structure at the end of the bronchioles?
What is the name of the structure at the end of the bronchioles?
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At which level does the laryngopharynx begin?
At which level does the laryngopharynx begin?
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What is the function of the pharynx in relation to speech?
What is the function of the pharynx in relation to speech?
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What is the location of the larynx in the neck?
What is the location of the larynx in the neck?
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What type of epithelium lines the wall of the larynx superior to the vocal fold?
What type of epithelium lines the wall of the larynx superior to the vocal fold?
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What is the alternative name for the trachea?
What is the alternative name for the trachea?
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What is the function of the tonsils in the pharynx?
What is the function of the tonsils in the pharynx?
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What percentage of oxygen from the lung is transported in combination with hemoglobin?
What percentage of oxygen from the lung is transported in combination with hemoglobin?
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What is the result of an increase in blood oxygen partial pressure on the oxygen-hemoglobin dissociation curve?
What is the result of an increase in blood oxygen partial pressure on the oxygen-hemoglobin dissociation curve?
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What is the effect of carbon dioxide and hydrogen ions on the oxygen dissociation curve?
What is the effect of carbon dioxide and hydrogen ions on the oxygen dissociation curve?
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What is the approximate amount of oxygen that 100ml of human blood can carry?
What is the approximate amount of oxygen that 100ml of human blood can carry?
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What is the amount of oxygen released to tissues in normal state?
What is the amount of oxygen released to tissues in normal state?
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What is the effect of carbon monoxide on oxygen carrying capacity of hemoglobin?
What is the effect of carbon monoxide on oxygen carrying capacity of hemoglobin?
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What is the composition of hemoglobin?
What is the composition of hemoglobin?
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What is the approximate factor by which oxygen release to tissues can increase during strenuous exercise?
What is the approximate factor by which oxygen release to tissues can increase during strenuous exercise?
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What is the primary direction of gas movement related to concentration?
What is the primary direction of gas movement related to concentration?
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What does the solubility coefficient represent?
What does the solubility coefficient represent?
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According to Henry's law, which of the following is true?
According to Henry's law, which of the following is true?
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How is the partial pressure of oxygen at sea level calculated if the concentration of oxygen is 21%?
How is the partial pressure of oxygen at sea level calculated if the concentration of oxygen is 21%?
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Which gas has a solubility coefficient of 0.57?
Which gas has a solubility coefficient of 0.57?
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What does the term 'partial pressure' refer to?
What does the term 'partial pressure' refer to?
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What determines the partial pressure of dissolved gases?
What determines the partial pressure of dissolved gases?
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Which of the following gases has a solubility coefficient of 0.024?
Which of the following gases has a solubility coefficient of 0.024?
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What does the diffusion coefficient of a gas represent?
What does the diffusion coefficient of a gas represent?
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Which factor increases the diffusion rate of gases through the respiratory membrane?
Which factor increases the diffusion rate of gases through the respiratory membrane?
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What is a common cause of decreased diffusion through the respiratory membrane?
What is a common cause of decreased diffusion through the respiratory membrane?
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How is the diffusion capacity of a gas through the respiratory membrane measured?
How is the diffusion capacity of a gas through the respiratory membrane measured?
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What happens to gas diffusion when the membrane thickness increases?
What happens to gas diffusion when the membrane thickness increases?
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Which of the following is NOT a factor that determines gas diffusion through the respiratory membrane?
Which of the following is NOT a factor that determines gas diffusion through the respiratory membrane?
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What is the normal diffusion capacity of oxygen in a resting man?
What is the normal diffusion capacity of oxygen in a resting man?
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Which condition is likely to increase the thickness of the respiratory membrane?
Which condition is likely to increase the thickness of the respiratory membrane?
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Study Notes
Structures of the Respiratory System
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Nasopharynx: Located behind the nasal cavity, extends to the soft palate, lined with pseudostratified ciliated columnar epithelium, facilitates equalization of air pressure between the middle ear and atmosphere via auditory tubes.
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Oropharynx: Serves both respiratory and digestive purposes, acts as a passage for air, food, and fluid, lined with nonkeratinized stratified squamous epithelium for abrasion protection.
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Laryngopharynx: Begins at the hyoid bone, opens to the esophagus and larynx, lined with nonkeratinized stratified squamous epithelium, facilitates air and food passage, acts as a resonating chamber for speech, houses tonsils for immune response.
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Larynx (Voice Box): Connects the laryngopharynx to the trachea, located anterior to the esophagus, has varying epithelial linings: nonkeratinized stratified squamous epithelium above vocal folds and pseudostratified ciliated columnar epithelium below.
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Trachea (Windpipe): Extends inferiorly from the larynx and divides the lungs into lobes, also features a right horizontal fissure that creates a middle lobe.
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Lung Parenchyma: Portion responsible for gas exchange, contains alveoli that open into alveolar ducts, crucial for respiratory function.
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Lobule of the Lung: Small compartments within bronchopulmonary segments, wrapped in elastic connective tissue, includes lymphatic vessels, arterioles, venules, and branches from terminal bronchioles.
Alveoli
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Alveolus: Cup-shaped sac at the bronchiole's end, main site for gas exchange, lined with two types of alveolar epithelial cells.
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Type I Alveolar Cells: Predominant in number, squamous cells forming a continuous lining for gas exchange.
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Type II Alveolar Cells: Fewer in number, secrete alveolar fluid and surfactant to maintain alveolar stability by lowering surface tension.
Gas Exchange Principles
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Partial Pressure: Concentration of gas in a mixture is proportional to its pressure, with gases diffusing from areas of higher to lower concentration.
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Concentration of Oxygen at Sea Level: The partial pressure of oxygen (21% of 760 mmHg) equals 160 mmHg.
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Henry’s Law: The relationship between partial pressure and solubility of gases, critical for understanding gas behavior in solutions.
Factors Affecting Gas Diffusion
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Thickness of Respiratory Membrane: Increased thickness reduces diffusion efficiency, commonly caused by ailments like edema or pulmonary fibrosis.
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Surface Area of Respiratory Membrane: Reduced surface area decreases diffusion, for example, due to removal of lung tissue or conditions like emphysema.
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Diffusion Coefficient: Indicator of diffusion rate, influenced by gas solubility and molecular weight.
Diffusion Capacity
- Diffusion Capacity: Volume of gas diffusing through the membrane per minute for a partial pressure difference of 1 mmHg. Normal oxygen diffusion capacity at rest is 21 ml/min/mmHg.
Hemoglobin and Oxygen Transport
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Oxygen Transportation: 97% of oxygen binds to hemoglobin (Hb) for transport; remaining 3% is dissolved in plasma.
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Hemoglobin Structure: Comprises 4 polypeptide chains (2 alpha, 2 beta), each with a heme group capable of binding oxygen.
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Oxygen-Carrying Capacity: A typical 100 ml blood contains 15 g of hemoglobin, allowing for an oxygen capacity of 20.1 ml, with approximately 5 ml released to tissues under normal conditions.
Oxygen-Hemoglobin Dissociation Curve
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Dissociation Curve: Reflects hemoglobin's oxygen saturation levels rising with increased blood oxygen partial pressure.
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Bohr Effect: An increase in carbon dioxide and hydrogen ions shifts the dissociation curve to the right, facilitating oxygen release to tissues.
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Carbon Monoxide Binding: CO competes with oxygen for hemoglobin binding sites with a much higher affinity, critically affecting oxygen transport efficiency.
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Description
This quiz covers the different structures of the respiratory system, including the nasopharynx, oropharynx, and laryngopharynx. Learn about their functions and characteristics.