Sheet 3 Physiology

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Questions and Answers

What happens if the amount of fluid in the interstitial space increases?

  • Edema occurs (correct)
  • The thickness of the respiratory membrane decreases
  • Airway resistance increases
  • Respiratory minute volume decreases

How is resistance (R) related to the cross-sectional area (A) of respiratory structures?

  • R is directly proportional to A
  • R is inversely proportional to A (correct)
  • R is directly proportional to A squared
  • R is inversely proportional to A squared

What is the relationship between airway resistance and permeability (K)?

  • They are directly related
  • There is no relationship between them
  • Permeability is directly related to airway resistance
  • Permeability is inversely related to airway resistance (correct)

How is airway resistance typically measured?

<p>Indirectly through pressure difference (B)</p> Signup and view all the answers

What driving force is needed to overcome resistance (R) according to the provided information?

<p>Pressure difference (∆P) (D)</p> Signup and view all the answers

What physiological condition leads to a constant flow of 6L/min when airway resistance = 1?

<p>Pressure difference = 1 (A)</p> Signup and view all the answers

During expiration, air you exhale first comes from which part of the respiratory system?

<p>Trachea (A)</p> Signup and view all the answers

What happens to the partial pressure of O2 in mixed air during expiration?

<p>It is highest in mixed expiration air (D)</p> Signup and view all the answers

In the respiratory tree, which generation does the trachea belong to?

<p>Generation #0 (C)</p> Signup and view all the answers

What does PDS stand for in the context of the respiratory system?

<p>Physiological Dead Space (A)</p> Signup and view all the answers

Which part of the respiratory system has a constant value of 150mm for WV?

<p>Anatomical dead space (B)</p> Signup and view all the answers

What happens when WV is greater than 0 in the respiratory system?

<p>{}PDS will be higher than ADS (D)</p> Signup and view all the answers

Which generation is considered the main site for gas exchange?

<p>Generation #17 (C)</p> Signup and view all the answers

What type of cells occupy 95% of the alveolus due to their thin squamous nature?

<p>Type 1 alveolar cells (A)</p> Signup and view all the answers

Which generation has cartilage for support and is not collapsible?

<p>Generation #3 (B)</p> Signup and view all the answers

What is the function of Type 2 alveolar cells?

<p>Secreting alveolar fluid including surfactant (C)</p> Signup and view all the answers

Which component of alveolar fluid is responsible for reducing surface tension?

<p>Phospholipids (D)</p> Signup and view all the answers

Why is airway resistance considered small and negligible?

<p>Because a very small pressure difference (∆𝑃) is needed to overcome the resistance. (C)</p> Signup and view all the answers

What is the relationship between airway resistance and cross-sectional area?

<p>Airway resistance increases with larger cross-sectional area. (B)</p> Signup and view all the answers

What causes most of the airway resistance in the respiratory system?

<p>Large airways. (A)</p> Signup and view all the answers

How does vascular resistance compare to airway resistance?

<p>Vascular resistance is 100 times greater than airway resistance. (C)</p> Signup and view all the answers

When does asthma become reversible according to the information provided?

<p>When bronchioles are more than 12% of total airway volume. (D)</p> Signup and view all the answers

Where does the air with the highest PO2 come from during mixed air expiration?

<p>Alveolar air (B)</p> Signup and view all the answers

Which part of the respiratory system has a constant value of 150mm for ADS?

<p>Trachea (B)</p> Signup and view all the answers

What is the generation number for the secondary bronchi in the respiratory tree?

<p>#2 (C)</p> Signup and view all the answers

Which type of cells occupy 95% of the alveoli due to their thin squamous nature?

<p>Type 1 alveolar cells (C)</p> Signup and view all the answers

What happens when the amount of fluid in the interstitial space increases?

<p>Impairs gas diffusion (B)</p> Signup and view all the answers

What is the main site for gas exchange in the respiratory system?

<p>Alveoli (D)</p> Signup and view all the answers

How many divisions/branches make up the respiratory tree?

<p>23 (A)</p> Signup and view all the answers

What is the main function of Type 2 alveolar cells?

<p>Produce alveolar fluid containing surfactant (C)</p> Signup and view all the answers

Why are generations #11 to #23 considered collapsible structures in the respiratory system?

<p>Supported by smooth muscles (A)</p> Signup and view all the answers

Which generation in the respiratory tree is responsible for gas exchange?

<p>#17 (A)</p> Signup and view all the answers

What is the primary function of Type 1 alveolar cells?

<p>Facilitate gas exchange (A)</p> Signup and view all the answers

Why is generation #23 referred to as the alveolus (closed bulb)?

<p>It marks the end of the respiratory tree (C)</p> Signup and view all the answers

Which type of cell occupies 5% of the alveolus and secretes surfactant?

<p>Type 2 alveolar cells (C)</p> Signup and view all the answers

What structures support generations #0 to #10 in the respiratory system?

<p>Cartilage (D)</p> Signup and view all the answers

What happens to the thickness of the respiratory membrane when there is an increase in fluid in the interstitial space?

<p>The thickness increases (C)</p> Signup and view all the answers

How is airway resistance related to permeability (K) in the respiratory system?

<p>Inversely proportional (B)</p> Signup and view all the answers

Which factor is used to overcome resistance (R) in the respiratory system?

<p>Pressure difference (∆P) (A)</p> Signup and view all the answers

How is airway resistance typically expressed when measuring it indirectly?

<p>Resistance = 1 (D)</p> Signup and view all the answers

What does a high value of resistance (R) indicate about the pressure difference required for flow?

<p>High pressure difference required (A)</p> Signup and view all the answers

Why is airway resistance considered a vague concept in the context of the respiratory system?

<p>It cannot be calculated accurately (C)</p> Signup and view all the answers

What factor is inversely related to airway resistance in the respiratory system?

<p>Cross-sectional area (A) (A)</p> Signup and view all the answers

Why is airway resistance considered small and negligible?

<p>The pressure difference () required to overcome airway resistance is minimal. (C)</p> Signup and view all the answers

What contributes to most of the airway resistance in the respiratory system?

<p>Presence of NET cross-sectional area in large divisions (C)</p> Signup and view all the answers

Why does vascular resistance in the cardiovascular system differ significantly from airway resistance?

<p>Vascular resistance is 100 times higher despite similar flow rates. (D)</p> Signup and view all the answers

What leads to the reversibility of asthma, as indicated in the text?

<p>When the flow through alveoli reaches 200ml. (D)</p> Signup and view all the answers

How does the NET cross-sectional area impact airway resistance?

<p>Increases airway resistance in large airways. (D)</p> Signup and view all the answers

What causes the significant difference in resistance between cardiovascular and respiratory systems?

<p>NET cross-sectional area variation between the systems. (C)</p> Signup and view all the answers

In what aspects do vascular and airway resistances differ significantly?

<p>Vascular resistance is much higher despite similar flow rates. (D)</p> Signup and view all the answers

During expiration, where does the air with the highest PCO2 come from in the respiratory system?

<p>Interstitial fluid (A)</p> Signup and view all the answers

Which generation of the respiratory tree is considered non-collapsible and has cartilage for support?

<p>Generation #7 (B)</p> Signup and view all the answers

In the context of the respiratory system, where do most of the airway resistances originate from?

<p>Tertiary bronchi (B)</p> Signup and view all the answers

Which part of the respiratory system contributes significantly to airway resistance due to its narrowing and branching?

<p>Terminal bronchioles (A)</p> Signup and view all the answers

In the given respiratory system hierarchy, which structure belongs to generation #0?

<p>Trachea (D)</p> Signup and view all the answers

Which part of the respiratory tree is associated with a constant value of 150mm for ADS?

<p>Trachea (D)</p> Signup and view all the answers

Based on the provided information, which part of the respiratory system serves as the primary site for gas exchange?

<p>Alveoli (A)</p> Signup and view all the answers

What is the relationship between resistance (R) and cross-sectional area (A) of respiratory structures?

<p>R is inversely proportional to A^2 (D)</p> Signup and view all the answers

What is a key difference between airway resistance and vascular resistance?

<p>Airway resistance is mainly realized in small airway divisions, whereas vascular resistance is in large vessels. (C)</p> Signup and view all the answers

Whose respiratory rate would have a higher resistance value according to the information provided?

<p>A person with a cardiac output of 5L/min and a flow of 6L/min (D)</p> Signup and view all the answers

How is airway resistance typically measured indirectly?

<p>By measuring the pressure difference (∆P) (A)</p> Signup and view all the answers

Why is the airway resistance considered negligible in comparison to vascular resistance?

<p>Airway resistance requires significantly less pressure to overcome. (A)</p> Signup and view all the answers

What does a high value of resistance (R) signify about the pressure difference needed for flow?

<p>Very high pressure difference needed (A)</p> Signup and view all the answers

What factor contributes significantly to the high resistance in large airways?

<p>The net cross-sectional area in small generations (D)</p> Signup and view all the answers

What is the opposite of airway resistance in the context of fluid dynamics?

<p>Permeability (C)</p> Signup and view all the answers

Why is airway resistance challenging to measure directly?

<p>Due to the difficulty in calculating r^4 for all respiratory structures (A)</p> Signup and view all the answers

When does asthma become reversible according to the information provided?

<p>When the bronchioles are more than 12% or 200ml (B)</p> Signup and view all the answers

What happens to the thickness of the respiratory membrane when there is an increase in fluid in the interstitial space?

<p>The thickness increases (C)</p> Signup and view all the answers

What contributes to most of the airway resistance in the respiratory system?

<p>Large cross-sectional areas in small generations (B)</p> Signup and view all the answers

What is the relationship between permeability (K) and airway resistance in the respiratory system?

<p>$K$ is inversely proportional to $R$ (A)</p> Signup and view all the answers

What is the main difference between generations #0 to #10 and generations #11 to #23 in the respiratory system?

<p>Generations #0 to #10 lack cartilage and are collapsible, while generations #11 to #23 have cartilage and are not collapsible. (C)</p> Signup and view all the answers

Which component of alveolar fluid is primarily responsible for reducing surface tension?

<p>Phospholipids (C)</p> Signup and view all the answers

What is the main function of Type 2 alveolar cells in the respiratory system?

<p>Surfactant production (A)</p> Signup and view all the answers

Which type of cell occupies 95% of the alveolus due to its thin squamous nature?

<p>Type 1 alveolar cell (C)</p> Signup and view all the answers

Why are generations #11 to #23 considered collapsible structures in the respiratory system?

<p>They are supported by smooth muscles. (C)</p> Signup and view all the answers

What is the diameter of an alveolus as mentioned in the provided information?

<p>$300$ micrometer (D)</p> Signup and view all the answers

What is the primary site for gas exchange in the respiratory system?

<p>#23 alveolus (B)</p> Signup and view all the answers

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