MPP II LECTURE 2.3 : RESPIRATORY PHARMACOLOGY

<p>Inhibiting COX-2 action and prostaglandin biosynthesis (B)</p> Signup and view all the answers

<p>Reduce hyperresponsiveness after months of regular use (B)</p> Signup and view all the answers

<p>Budesonide (B)</p> Signup and view all the answers

<p>IC = TV + IRV (D)</p> Signup and view all the answers

<p>Decreasing the inflammatory cascade (A)</p> Signup and view all the answers

<p>Inhalation (C)</p> Signup and view all the answers

<p>TLC=TV+IRV+ERV+RV (D)</p> Signup and view all the answers

<p>Promoting bronchodilation by activating β2-adrenergic receptors on smooth muscle cells of the airways. (B)</p> Signup and view all the answers

<p>Loss of lung elasticity (D)</p> Signup and view all the answers

<p>Promoting bronchodilation by blocking muscarinic receptors on bronchial smooth muscle. (A)</p> Signup and view all the answers

<p>Inhaled corticosteroids (C)</p> Signup and view all the answers

<p>Reducing airway inflammation (D)</p> Signup and view all the answers

<p>Decreased FEV1/FVC ratio (C)</p> Signup and view all the answers

<p>Irreversible loss of lung elasticity (C)</p> Signup and view all the answers

<p>Relaxation of bronchial smooth muscle (D)</p> Signup and view all the answers

<p>Decreased inflammatory mediator release (D)</p> Signup and view all the answers

<p>A largely irreversible reduction in FEV1, even after bronchodilator use (B)</p> Signup and view all the answers

<p>Increases cardiac output by improving contractility and rate of contraction (B)</p> Signup and view all the answers

<p>Treating acute asthma symptoms (B)</p> Signup and view all the answers

<p>LABA provides sustained bronchodilation for over 12 hours (D)</p> Signup and view all the answers

<p>Tachycardia or arrhythmia (B)</p> Signup and view all the answers

<p>They bind to adrenergic receptors on effector organs without engaging the presynaptic neuron (A)</p> Signup and view all the answers

<p>Budesonide and formoterol (D)</p> Signup and view all the answers

<p>Has a longer duration of action requiring only once daily administration (A)</p> Signup and view all the answers

<p>Epinephrine (B)</p> Signup and view all the answers

<p>Chronic kidney disease (A)</p> Signup and view all the answers

<p>Bronchodilation (A)</p> Signup and view all the answers

Study of agents acting on catecholamine pathways, like norepinephrine and epinephrine.

Agents that bind directly to adrenergic receptors without affecting presynaptic neurons.

Agonist at both α- and β-adrenoceptors, important in cardiovascular and respiratory functions.

Expansion of the air passages in the respiratory system, primarily through β2 receptor action.

Short-acting β2 agonist used for quick relief of asthma symptoms.

Short-Acting Beta Agonists used for quick bronchodilation.

Long-Acting Beta Agonists for sustained bronchodilation, effective for over 12 hours.

Combination therapy; ICS + LABA to control inflammation and improve airflow.

Agents that block muscarinic receptors, interrupting parasympathetic effects.

Antagonists like ipratropium and tiotropium, used for COPD management.

Key features include bronchoconstriction, inflammation, and loss of lung elasticity.

A narrowing of the airways that restricts airflow, often treated with adrenergic agonists.

Medications that stimulate adrenergic receptors to relax bronchial smooth muscles.

Medications that block cholinergic receptors, helping to dilate airways.

Anti-inflammatory drugs used to reduce airway inflammation in asthma and COPD.

Chronic Obstructive Pulmonary Disease characterized by airflow limitation and breathing difficulties.

A specific type of corticosteroid delivered directly to the lungs to manage asthma.

Total Lung Capacity, the total volume of air in the lungs.

A test used to measure lung function, assessing the volume and speed of air during inhalation and exhalation.

Expiratory Reserve Volume, air that can be forcibly exhaled after normal expiration.

Functional Residual Capacity, the volume of air remaining in lungs after normal expiration.

Asthma is often reversible with treatment; COPD is progressive and generally irreversible.

Refers to the ability of the lungs to take in oxygen and expel carbon dioxide effectively.

A test that measures lung function by assessing the volume and speed of air exhalation.

Medications for long-term asthma control by reducing airway inflammation.

Mechanism where ICS reduce inflammation by inhibiting COX-2 and prostaglandin production.

ICS do not directly affect airway smooth muscle but target inflammation.

An example of an Inhaled Corticosteroid (Qvar) used in asthma treatment.

Asthma classification that includes daily symptoms and the need for a rescue inhaler.

The amount of air left in the lungs after a maximal exhalation.