Respiratory Membrane Quiz

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the primary purpose of the respiratory membrane?

  • To facilitate gas exchange (correct)
  • To protect the lungs from infections
  • To produce pulmonary surfactant
  • To filter air before it enters the lungs

The diffusion of gas is enhanced by a thick respiratory membrane.

False (B)

What two structures make up the respiratory membrane?

The wall of the alveolus and the wall of the pulmonary capillary.

Gas exchange occurs by ________ across the respiratory membrane.

<p>diffusion</p> Signup and view all the answers

Which factor is NOT mentioned as influencing the effectiveness of gas diffusion?

<p>Temperature of the gas (A)</p> Signup and view all the answers

Match the factors affecting gas diffusion with their descriptions:

<p>High driving force = Increases the partial pressure gradient Short diffusion distance = Provided by a thin respiratory membrane Pulmonary surfactant = Helps increase compliance Efficient diffusion = Result of the combined factors</p> Signup and view all the answers

Pulmonary surfactant primarily aids in gas exchange directly.

<p>False (B)</p> Signup and view all the answers

Name one factor that determines the effectiveness of gas diffusion.

<p>High driving force for diffusion or short diffusion distance.</p> Signup and view all the answers

What is the total thickness of the alveolar and capillary walls combined?

<p>0.5 µm (C)</p> Signup and view all the answers

Only oxygen (O2) needs to dissolve in the alveolar fluid before diffusion occurs.

<p>False (B)</p> Signup and view all the answers

How many alveoli are there approximately in the human lungs?

<p>500 million</p> Signup and view all the answers

Carbon dioxide (CO2) is approximately ___ times more soluble than oxygen (O2).

<p>20</p> Signup and view all the answers

Match the following components with their descriptions:

<p>Type I alveolar cells = Flattened cells making up the alveolar wall Haemoglobin = Protein that binds O2 in the blood Capillaries = Encircle the alveoli for gas exchange Alveolar fluid = Lining where gas must dissolve before diffusion</p> Signup and view all the answers

The total surface area available for gas exchange in the lungs is approximately 75 m².

<p>True (A)</p> Signup and view all the answers

What is the primary function of the alveoli in the lungs?

<p>Gas exchange</p> Signup and view all the answers

The respiratory membrane consists of the ___ wall and the ___ wall.

<p>alveolar, capillary</p> Signup and view all the answers

What percentage of atmospheric pressure is contributed by nitrogen (N2)?

<p>79% (A)</p> Signup and view all the answers

The total atmospheric pressure is made up entirely of oxygen (O2).

<p>False (B)</p> Signup and view all the answers

What is the typical partial pressure of oxygen (PO2) in the lungs?

<p>100 mmHg</p> Signup and view all the answers

In atmospheric air, the partial pressure of nitrogen is ___ mmHg.

<p>600</p> Signup and view all the answers

Match the gas with its corresponding role in atmospheric pressure:

<p>N2 = 79% atmospheric pressure O2 = 21% atmospheric pressure CO2 = Minor component Ar = Inert gas in atmosphere</p> Signup and view all the answers

What happens to the diffusion of oxygen (O2) when the partial pressures are equal?

<p>Diffusion stops (C)</p> Signup and view all the answers

The partial pressure of a gas contributes to its diffusion force.

<p>True (A)</p> Signup and view all the answers

What is the driving force for gas diffusion?

<p>Partial pressure</p> Signup and view all the answers

The driving force for gas diffusion in the lungs is maintained through a ___ pressure gradient.

<p>partial</p> Signup and view all the answers

What is the calculated partial pressure of nitrogen (PN2) at sea level (760 mmHg)?

<p>600 mmHg (A)</p> Signup and view all the answers

What is primarily responsible for increasing the surface area of food in the stomach?

<p>Mastication (B)</p> Signup and view all the answers

Clinical conditions like Crohn’s disease do not affect the surface area for absorption in the small intestine.

<p>False (B)</p> Signup and view all the answers

What does cholera toxin chronically activate?

<p>CFTR Cl- channel</p> Signup and view all the answers

The main function of villi in the small intestine is __________.

<p>absorption</p> Signup and view all the answers

Match the disease with its effect on intestinal absorption:

<p>Diverticulitis = Multiple pouches in the colon Coeliac disease = Blunting of villi Crohn’s disease = Deep ulceration in the bowel Cholera = Fluid loss due to toxin</p> Signup and view all the answers

Which of the following cells is primarily responsible for secreting mucous in the intestines?

<p>Goblet cells (A)</p> Signup and view all the answers

Kwashiorkor is a form of malnutrition that occurs due to protein deficiency.

<p>True (A)</p> Signup and view all the answers

What is the primary problem caused by diverticula in the intestines?

<p>Abscess formation</p> Signup and view all the answers

Microvilli are found on the __________ of enterocytes.

<p>apical surface</p> Signup and view all the answers

What triggers the immune response in coeliac disease?

<p>Undeamidated gliadin (D)</p> Signup and view all the answers

Plicae circularis are small finger-like projections in the large intestine.

<p>False (B)</p> Signup and view all the answers

What are the major two forms of malnutrition associated with starvation?

<p>Kwashiorkor and Marasmus</p> Signup and view all the answers

__________ is the main factor in facilitating diffusion of gases across the respiratory membrane.

<p>Surface area</p> Signup and view all the answers

Which of the following is a function of pepsinogen in the stomach?

<p>Protein digestion (B)</p> Signup and view all the answers

Match the following absorption problems with their corresponding conditions:

<p>Diverticulitis = Pouch formations Crohn's disease = Skewed nutrient absorption Coeliac disease = Villi damage Cholera = Fluid loss</p> Signup and view all the answers

What can occur when ventilation is compromised?

<p>Hypoxaemia (B)</p> Signup and view all the answers

Bronchoconstriction results in good ventilation.

<p>False (B)</p> Signup and view all the answers

What is the normal partial pressure of oxygen (PO2) in the alveoli?

<p>100 mmHg</p> Signup and view all the answers

Ventilation-perfusion matching helps to maintain a high level of ____ in the blood.

<p>oxygen</p> Signup and view all the answers

Match the following conditions with their effects on ventilation:

<p>Bronchoconstriction = Poor ventilation Good airflow = Normal PO2 levels Poor ventilation = Hypoxaemia High oxygen blood = Sufficient blood oxygenation</p> Signup and view all the answers

Which statement is true regarding maternal and fetal oxygen levels?

<p>Fetal oxygen levels are generally lower than maternal levels (A)</p> Signup and view all the answers

Alveolar PO2 levels can drop significantly without causing hypoxaemia.

<p>False (B)</p> Signup and view all the answers

What physiological mechanism helps redirect blood vessels in the pulmonary system?

<p>Local controls on smooth muscle</p> Signup and view all the answers

When blood passes through the alveoli with a PO2 of 40 mmHg, it indicates ____ oxygen levels.

<p>low</p> Signup and view all the answers

What effect does poor ventilation have on oxygen levels?

<p>Decreased oxygen levels (A)</p> Signup and view all the answers

What happens in a lung region when there is a decrease in CO2 concentration?

<p>Constriction of bronchioles (A)</p> Signup and view all the answers

Increased CO2 concentration leads to the dilation of bronchioles.

<p>True (A)</p> Signup and view all the answers

What is the primary effect of a greater blood flow than airflow in the lungs?

<p>It helps balance CO2 in the lung region.</p> Signup and view all the answers

When airflow is greater than blood flow, there is _____ of local pulmonary artery smooth muscle.

<p>contraction</p> Signup and view all the answers

Match the following scenarios with their respective effects:

<p>Large blood flow = Constriction of local blood vessels Small airflow = Dilation of local airways Large airflow = Contraction of local pulmonary artery smooth muscle Small blood flow = Relaxation of local airways</p> Signup and view all the answers

What balance is achieved when CO2 concentration is high in a lung region?

<p>Larger blood flow (A)</p> Signup and view all the answers

Airway resistance increases when blood flow is greater than airflow.

<p>False (B)</p> Signup and view all the answers

What is the partial pressure of oxygen (PO2) in the region with constricted blood flow?

<p>94 mmHg</p> Signup and view all the answers

Under conditions of increased blood flow, local airways experience _____ of smooth muscle.

<p>relaxation</p> Signup and view all the answers

What is the effect of small blood flow in a lung region?

<p>Increased airway resistance (B)</p> Signup and view all the answers

Flashcards

Gastric ulcer base

The part of a gastric ulcer that is free of tissue damage.

Surface area (digestion)

The crucial importance of a large surface area within the digestive system for effective breakdown and absorption of food.

Mastication

The mechanical breakdown of food in the mouth.

Small intestine's surface area

Enormous surface in the small intestine, crucial for absorption.

Signup and view all the flashcards

Plicae circularis

Large folds in the small intestine.

Signup and view all the flashcards

Villus

Finger-like projections in the small intestine.

Signup and view all the flashcards

Microvilli

Tiny projections on the surface of villi.

Signup and view all the flashcards

Coeliac disease

Autoimmune disorder where the immune system attack the villi.

Signup and view all the flashcards

Diverticulitis

Inflammation of small pouches lining the digestive tract.

Signup and view all the flashcards

Cholera toxin

A toxin that chronically activates a channel in the body.

Signup and view all the flashcards

CFTR Cl- channel

A chloride channel in the body activated by Cholera toxin.

Signup and view all the flashcards

Kwashiorkor and Marasmus

Protein deficiency malnutrition.

Signup and view all the flashcards

Respiratory membrane diffusion

Factors affecting gas exchange and oxygen transfer across the respiratory membrane.

Signup and view all the flashcards

Alveolar Wall

A single layer of flattened Type I alveolar cells, responsible for gas exchange.

Signup and view all the flashcards

Capillary Wall

A single layer of endothelium, surrounding the alveoli and facilitating gas exchange.

Signup and view all the flashcards

Respiratory Membrane

Combined structure of the alveolar wall and capillary wall, allowing gas diffusion.

Signup and view all the flashcards

Surface Area for Gas Exchange

The total area of the alveoli available for oxygen and carbon dioxide diffusion.

Signup and view all the flashcards

Solubility of Gases

Tendency of a gas to dissolve in a liquid, affecting diffusion rate.

Signup and view all the flashcards

Oxygen Diffusion

Movement of oxygen from alveoli into the capillaries.

Signup and view all the flashcards

Carbon Dioxide Diffusion

Movement of carbon dioxide from capillaries into the alveoli.

Signup and view all the flashcards

Haemoglobin

Protein in red blood cells that binds to oxygen for transport throughout the body.

Signup and view all the flashcards

Alveolus

A tiny air sac in the lungs where gas exchange takes place.

Signup and view all the flashcards

Pulmonary Capillary

A tiny blood vessel in the lungs that surrounds the alveoli.

Signup and view all the flashcards

Diffusion

The movement of molecules from an area of high concentration to an area of low concentration.

Signup and view all the flashcards

Driving Force for Diffusion

The difference in partial pressure of a gas between two areas, causing movement of molecules.

Signup and view all the flashcards

Partial Pressure Gradient

The difference in pressure of a specific gas between two areas.

Signup and view all the flashcards

Diffusion Distance

The distance that molecules need to travel during diffusion.

Signup and view all the flashcards

Pulmonary Surfactant

A substance produced by type II cells in the alveoli that helps reduce surface tension and keeps alveoli open.

Signup and view all the flashcards

Partial Pressure

The pressure exerted by a specific gas in a mixture of gases. It's a driving force for gas diffusion, determining the movement of gases between areas of different concentrations.

Signup and view all the flashcards

What drives gas diffusion?

The difference in partial pressure between two areas drives the movement of gases. Gases will naturally move from areas of higher partial pressure to areas of lower partial pressure to reach equilibrium.

Signup and view all the flashcards

PN2 in the atmosphere

The partial pressure of nitrogen (N2) in atmospheric air is approximately 600 mm Hg. This is calculated by multiplying the percentage of nitrogen in air (79%) by the total atmospheric pressure (760 mm Hg).

Signup and view all the flashcards

Alveolar PO2

The partial pressure of oxygen (PO2) in the alveoli of the lungs is typically around 100 mmHg. This is higher than the PO2 in the blood, driving oxygen diffusion into the bloodstream.

Signup and view all the flashcards

How does PO2 affect diffusion?

When oxygen diffuses from the alveoli into the bloodstream, the PO2 in the alveoli decreases, which is a driving force for more oxygen to move into the bloodstream.

Signup and view all the flashcards

Why is partial pressure important?

Partial pressure is crucial because it determines the movement and exchange of gases in the lungs and bloodstream. This is essential for delivering oxygen to the body's tissues and removing carbon dioxide.

Signup and view all the flashcards

How is partial pressure maintained?

The body maintains a pressure gradient by constantly replenishing oxygen into the lungs through breathing, and by removing carbon dioxide from the bloodstream.

Signup and view all the flashcards

What happens when partial pressure is equal?

When the partial pressure of a gas is equal between two areas, there is no net movement of that gas. This is called equilibrium.

Signup and view all the flashcards

Oxygen concentration in blood

The concentration of oxygen in blood is approximately 5.20 mmol/liter. This is maintained by the continuous diffusion of oxygen from the alveoli into the bloodstream.

Signup and view all the flashcards

What is the role of the respiratory membrane?

The respiratory membrane acts as a barrier between the alveoli and the capillaries. The thickness and surface area of this membrane influence the rate of gas exchange.

Signup and view all the flashcards

Ventilation-Perfusion Matching

The balanced relationship between airflow (ventilation) and blood flow (perfusion) in the lungs, ensuring efficient gas exchange.

Signup and view all the flashcards

Constricted Bronchioles

Narrowed airways in a lung region due to low CO2 concentration. This reduces airflow to that specific region.

Signup and view all the flashcards

Dilated Bronchioles

Widened airways in a lung region due to high CO2 concentration. Allows for increased airflow to that region.

Signup and view all the flashcards

Blood Flow (Perfusion)

The amount of blood passing through the blood vessels in a specific lung region.

Signup and view all the flashcards

Airflow (Ventilation)

The movement of air in and out of the lungs, through the airways.

Signup and view all the flashcards

PO2

Partial pressure of oxygen, indicating the amount of oxygen dissolved in the blood.

Signup and view all the flashcards

High PO2

Indicates high oxygen levels in the blood, typically in areas of well-ventilated lungs.

Signup and view all the flashcards

Low PO2

Indicates low oxygen levels in the blood, often in areas of poor ventilation or blood flow.

Signup and view all the flashcards

CO2 Concentration

The amount of carbon dioxide present in a specific lung region.

Signup and view all the flashcards

Smooth Muscle Relaxation

The relaxation of muscle cells in the airways, resulting in dilation and increased airflow.

Signup and view all the flashcards

Hypoxaemia

Low oxygen levels in the blood.

Signup and view all the flashcards

What compromises ventilation- perfusion matching?

Conditions that disrupt the balance between airflow and blood flow in the alveoli, leading to reduced oxygen uptake. These conditions include bronchoconstriction, poor ventilation, and reduced blood flow to the lungs due to conditions like pulmonary embolism.

Signup and view all the flashcards

How does bronchoconstriction affect ventilation-perfusion matching?

Bronchoconstriction narrows the airways, reducing airflow and leading to a mismatch between ventilation and perfusion. This can result in hypoxaemia.

Signup and view all the flashcards

Local controls on pulmonary blood vessels

The smooth muscle of the pulmonary arteries can constrict or dilate in response to local factors like oxygen levels. This helps to redirect blood flow to areas of the lung with better ventilation.

Signup and view all the flashcards

How do local controls help maintain oxygen levels?

Local controls on the pulmonary blood vessels help to ensure that blood is directed to areas of the lung with good ventilation, maximizing oxygen uptake.

Signup and view all the flashcards

What happens to the blood in poorly ventilated areas?

In poorly ventilated areas of the lung, blood may not receive sufficient oxygen, resulting in a lower oxygen content compared to blood in well-ventilated areas.

Signup and view all the flashcards

Why PO2 is higher in alveoli than in blood?

Alveoli have a higher partial pressure of oxygen (PO2) because they are directly exposed to inspired air, while blood entering the lungs has a lower PO2.

Signup and view all the flashcards

What is the result of ventilation-perfusion mismatch?

Ventilation-perfusion mismatch can cause hypoxaemia because the blood doesn't pick up enough oxygen in the lungs.

Signup and view all the flashcards

How does the body compensate for ventilation-perfusion mismatch?

The body tries to compensate by redirecting blood flow to better ventilated areas and increasing respiratory rate and depth to improve oxygen intake.

Signup and view all the flashcards

Study Notes

Respiratory Membrane

  • The primary purpose of the respiratory membrane is to facilitate gas exchange between the air in the alveoli and the blood in the capillaries.
  • The respiratory membrane is made up of two structures: the thin wall of the alveoli and the thin wall of the capillaries.
  • Gas exchange occurs by diffusion across the respiratory membrane.
  • The effectiveness of gas diffusion is NOT influenced by the thickness of the respiratory membrane.

Factors Affecting Gas Diffusion

  • Pulmonary surfactant aids in gas exchange by reducing surface tension in the alveoli, which prevents them from collapsing.
  • Partial pressure gradient is a key factor determining the effectiveness of gas diffusion.
  • The total thickness of the alveolar and capillary walls combined is 0.5 micrometers.
  • Oxygen (O2) needs to dissolve in the alveolar fluid before diffusion occurs.
  • There are approximately 300 million alveoli in the human lungs.
  • Carbon dioxide (CO2) is approximately 20 times more soluble than oxygen (O2).

Components of the Respiratory Membrane and Gas Exchange

  • The total surface area available for gas exchange in the lungs is approximately 75 m².
  • The primary function of the alveoli in the lungs is gas exchange.
  • The respiratory membrane consists of the alveolar wall and the capillary wall.
  • Nitrogen (N2) contributes 78% of atmospheric pressure.
  • The total atmospheric pressure is NOT made up entirely of oxygen (O2).
  • The typical partial pressure of oxygen (PO2) in the lungs is 100 mmHg.
  • In atmospheric air, the partial pressure of nitrogen is 593 mmHg.

Gas Diffusion and Partial Pressure

  • Nitrogen (N2) is the primary component of atmospheric pressure.
  • Oxygen (O2) makes up 21% of atmospheric pressure.
  • Carbon dioxide (CO2) contributes 0.04% to atmospheric pressure.
  • Diffusion of oxygen (O2) stops when the partial pressures are equal.
  • The partial pressure of a gas contributes to its diffusion force.
  • The driving force for gas diffusion is the difference in partial pressure between the alveoli and the blood.
  • The driving force for gas diffusion in the lungs is maintained through a pressure gradient.
  • The calculated partial pressure of nitrogen (PN2) at sea level (760 mmHg) is 593 mmHg.

Intestinal Absorption

  • Plicae circularis, villi, and microvilli are all features that increase the surface area of the small intestine for absorption.
  • Cholera toxin chronically activates adenylate cyclase.
  • The main function of villi in the small intestine is absorption of nutrients.
  • Crohn's disease affects the surface area for absorption in the small intestine.
  • Celiac disease triggers the immune response through gluten.
  • Kwashiorkor is a form of malnutrition that occurs due to protein deficiency.
  • Diverticula in the intestines can cause inflammation, pain, and bleeding.
  • Microvilli are found on the apical surface of enterocytes.
  • Plicae circularis are small finger-like projections in the small intestine.
  • The two major forms of malnutrition associated with starvation are marasmus and kwashiorkor.

Factors Affecting Gas Diffusion

  • The partial pressure gradient is the main factor facilitating diffusion of gases across the respiratory membrane.
  • Pepsinogen in the stomach functions as a precursor to pepsin, which breaks down proteins.
  • Lactose intolerance is a condition caused by a deficiency in lactase, leading to lactose malabsorption.
  • Celiac disease is triggered by gluten, leading to damage in the small intestine and malabsorption.
  • Crohn's disease can cause malabsorption due to inflammation and damage in the small intestine.

Ventilation and Gas Exchange

  • When ventilation is compromised, hypoxia can occur due to decreased oxygen levels in the blood.
  • Bronchoconstriction does NOT result in good ventilation.
  • The normal partial pressure of oxygen (PO2) in the alveoli is 100 mmHg.
  • Ventilation-perfusion matching helps maintain a high level of oxygen in the blood.
  • Asthma can cause airway narrowing and increased airway resistance.
  • Pneumonia causes inflammation in the lungs, leading to decreased gas exchange.
  • Pulmonary embolism blocks blood flow to the lungs, decreasing gas exchange.
  • Chronic obstructive pulmonary disease (COPD) is a condition characterized by airflow limitation and difficulty exhaling.
  • Emphysema causes damage to the alveoli, reducing the surface area for gas exchange.

Maternal and Fetal Oxygen Levels

  • Maternal and fetal oxygen levels are NEVER equal due to the barrier presented by the placenta.
  • Alveolar PO2 levels can drop significantly without causing hypoxaemia.
  • The hypoxic vasoconstriction mechanism helps redirect blood vessels in the pulmonary system.
  • When blood passes through the alveoli with a PO2 of 40 mmHg, it indicates low oxygen levels.
  • Poor ventilation results in decreased oxygen levels.
  • In a lung region with a decrease in CO2 concentration, bronchoconstriction occurs.
  • Increased CO2 concentration leads to the dilation of bronchioles.

Ventilation-Perfusion Matching

  • A greater blood flow than airflow in the lungs results in shunting, where poorly oxygenated blood bypasses the alveoli.
  • When airflow is greater than blood flow, there is constriction of local pulmonary artery smooth muscle.
  • When CO2 concentration is high in a lung region, a balance is achieved by constricting blood flow and dilating airways.
  • Airway resistance increases when blood flow is greater than airflow.
  • The partial pressure of oxygen (PO2) in the region with constricted blood flow is lower than in regions with normal blood flow.
  • Under conditions of increased blood flow, local airways experience dilation of smooth muscle.
  • Small blood flow in a lung region results in vasoconstriction of pulmonary arterioles.

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Quiz Team

Related Documents

NURS1005 Final Lectures PDF
Use Quizgecko on...
Browser
Browser