Research in Humans: Chapter 2

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Questions and Answers

What is the main difference between research in humans and other research?

  • There are no rules or procedures to protect human participants
  • The research is less important than other types of research
  • The human subject has no decision-making power
  • The human subject has decision-making power (correct)

What was the purpose of establishing elaborate rules and procedures to protect human participants in research?

  • To prevent exploitation of human subjects (correct)
  • To discourage human participation in research
  • To limit the scope of medical experiments on humans
  • To make research more difficult

According to the Nuremberg Code 1947, what is the principle related to voluntary informed consent?

  • Beneficence
  • Autonomy (correct)
  • Non-maleficence
  • Justice

Which principle from the Nuremberg Code 1947 emphasizes good science and favorable benefit to risk ratio?

<p>Beneficence (A)</p> Signup and view all the answers

What was the responsibility of the investigator according to the Nuremberg Code 1947?

<p>Ensuring ethical requirements were met (B)</p> Signup and view all the answers

Why did the Nuremberg Code 1947 emphasize equal opportunity to participate and to not participate?

<p>To ensure fairness and respect for individual choices (B)</p> Signup and view all the answers

What is the primary responsibility of physicians according to the Declaration of Helsinki?

<p>The best care, with research being secondary (A)</p> Signup and view all the answers

What is the main provision of the Belmont Report regarding 'Research'?

<p>A systematic investigation to develop or contribute to generalizable knowledge (A)</p> Signup and view all the answers

What does 'Human Subject' refer to according to the Belmont Report?

<p>An individual about whom an investigator obtains data through intervention or interaction (D)</p> Signup and view all the answers

What is the requirement for consent in research involving human subjects according to the Declaration of Helsinki?

<p>It must be voluntary and informed, with documented consent and ability to withdraw (D)</p> Signup and view all the answers

What is the primary focus when scrutinizing a research protocol according to the Declaration of Helsinki?

<p>Risks and benefits, with minimization of risks and maximization of benefits (B)</p> Signup and view all the answers

What is required for the population studied in research involving humans according to the Declaration of Helsinki?

<p>A reasonable chance of benefiting from the results (C)</p> Signup and view all the answers

What is the limitation placed on jointly providing clinical care and research by the Declaration of Helsinki?

<p>A limitation was placed on jointly providing clinical care and research (D)</p> Signup and view all the answers

'Placebo use' in research involving human subjects is strictly limited according to which document?

<p>Declaration of Helsinki (C)</p> Signup and view all the answers

'Intervention' in research refers to which of the following according to the Belmont Report?

<p>Physical procedures and manipulations for research purposes (D)</p> Signup and view all the answers

'Private Information' in research refers to which of the following according to the Belmont Report?

<p>'Private Information' refers to behavior that occurs in a context where no observation or recording is taking place (C)</p> Signup and view all the answers

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