Reproductive System Overview and Gametogenesis
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Questions and Answers

What is the primary hormone produced by the male gonads during gonadarche?

  • Progesterone
  • Testosterone (correct)
  • Estrogen
  • Insulin
  • What is a characteristic feature of the male climacteric?

  • Stable sperm production
  • Decrease in testicular volume (correct)
  • Enhanced libido
  • Increased estrogen production
  • At what age range does adrenarche typically begin?

  • 14-16 years
  • 2-4 years
  • 6-8 years (correct)
  • 10-12 years
  • What happens to the ovaries during the female climacteric?

    <p>They become devoid of follicles (B)</p> Signup and view all the answers

    Which of the following is NOT a symptom of reduced circulating testosterone levels in males?

    <p>Increased hair growth (D)</p> Signup and view all the answers

    What is the primary function of the fimbriae in the infundibulum?

    <p>To sweep oocytes into the ostium (C)</p> Signup and view all the answers

    Which region of the fallopian tubes is known as the site of fertilization?

    <p>Ampulla (D)</p> Signup and view all the answers

    What is the main purpose of the two smooth muscle layers in the middle layer of the uterine tubes?

    <p>To transport the oocyte/blastocyst to the uterus (B)</p> Signup and view all the answers

    How is the inner layer of the uterine tubes characterized?

    <p>Highly-folded mucosa lined with ciliated epithelium (C)</p> Signup and view all the answers

    Which part of the uterus is identified as the narrow region?

    <p>Isthmus (D)</p> Signup and view all the answers

    What process do females undergo to produce gametes?

    <p>Oogenesis (C)</p> Signup and view all the answers

    Which structure directly supports germ cell development within the seminiferous tubules?

    <p>Sertoli cells (C)</p> Signup and view all the answers

    What is the primary function of the prostate gland?

    <p>Secretes seminal fluid (A)</p> Signup and view all the answers

    At what stage does spermatogenesis begin?

    <p>At puberty (B)</p> Signup and view all the answers

    Which part of the male reproductive tract is primarily involved in sperm maturation?

    <p>Epididymis (B)</p> Signup and view all the answers

    What is the main component that allows sperm to swim?

    <p>Flagellum (C)</p> Signup and view all the answers

    What type of tissue is the ductus deferens primarily made of?

    <p>Smooth muscle (C)</p> Signup and view all the answers

    How long does it take for spermatogenesis to complete?

    <p>74 days (A)</p> Signup and view all the answers

    Which gland contributes to the first fraction of ejaculate?

    <p>Bulbourethral gland (C)</p> Signup and view all the answers

    What does the term 'gametogenesis' refer to?

    <p>The production of gametes (A)</p> Signup and view all the answers

    What distinguishes sex from gender?

    <p>Sex is biological, gender is social (A)</p> Signup and view all the answers

    Which phase in oogenesis occurs before puberty?

    <p>Oogonia proliferation (C)</p> Signup and view all the answers

    Which anatomical feature separates the two testes?

    <p>Tunica albuginea (D)</p> Signup and view all the answers

    The seminal vesicles primarily contribute to which aspect of male reproduction?

    <p>Semen volume (D)</p> Signup and view all the answers

    What is the primary function of the corpora spongiosum during an erection?

    <p>To maintain the functional pathway of the urethra (A)</p> Signup and view all the answers

    What temperature does the scrotum maintain for optimal spermatogenesis?

    <p>34°C (C)</p> Signup and view all the answers

    Which cells are responsible for the conversion of androgens into estrogen during folliculogenesis?

    <p>Granulosa cells (C)</p> Signup and view all the answers

    What happens to the corpus luteum if pregnancy does not occur?

    <p>It forms into a corpus albicans (D)</p> Signup and view all the answers

    Which structure houses the testes, epididymis, and proximal portion of the ductus deferens?

    <p>Scrotum (D)</p> Signup and view all the answers

    What is the position of the ovaries in relation to the uterus?

    <p>On either side of the uterus (D)</p> Signup and view all the answers

    What ensures blood enters the corpora cavernosa during sexual arousal?

    <p>Cavernosal artery (C)</p> Signup and view all the answers

    What feature of the tertiary follicle allows the oocyte to be isolated?

    <p>Expansion of antrum (B)</p> Signup and view all the answers

    How are the ovarian arteries, veins, and nerves structured in relation to the ovary?

    <p>They converge at the hilum of the ovary (D)</p> Signup and view all the answers

    What is the main role of the mesovarium in relation to the ovaries?

    <p>To anchor the ovaries (C)</p> Signup and view all the answers

    During which stage does the corpus luteum secrete hormones?

    <p>Only if pregnancy occurs (C)</p> Signup and view all the answers

    What distinguishes the median compartment of the scrotum?

    <p>It bisects the two testicular compartments (B)</p> Signup and view all the answers

    What is the primary purpose of the cilia in the uterine ducts?

    <p>To assist in the movement of the ovum (D)</p> Signup and view all the answers

    Which type of cells are formed from the development of thecal cells?

    <p>Luteal cells (A)</p> Signup and view all the answers

    What is the primary function of the cervix in the female reproductive system?

    <p>Serving as a passageway for the fetus during birth (A)</p> Signup and view all the answers

    Which layer of the uterus is directly involved in implantation?

    <p>Functional layer (C)</p> Signup and view all the answers

    What structure links the uterus to the vagina?

    <p>Cervical canal (D)</p> Signup and view all the answers

    What is the role of the functional layer of the endometrium?

    <p>To respond to hormonal changes and nourish a developing embryo (C)</p> Signup and view all the answers

    What is the primary structure found in the vestibule of female external genitalia?

    <p>Vaginal orifice (B)</p> Signup and view all the answers

    Which hormone initiates the release of gonadotropins from the anterior pituitary?

    <p>GnRH (B)</p> Signup and view all the answers

    During which phase do estrogen levels peak, promoting a positive feedback leading to an LH surge?

    <p>Mid-follicular phase (C)</p> Signup and view all the answers

    What is the primary function of the clitoris in the female reproductive anatomy?

    <p>To contribute to sexual arousal and pleasure (A)</p> Signup and view all the answers

    Which hormone is primarily responsible for preparing the endometrium for implantation?

    <p>Progesterone (D)</p> Signup and view all the answers

    What does the basal layer of the endometrium provide during the menstrual cycle?

    <p>Source of arteries and glands for the functional layer (B)</p> Signup and view all the answers

    Which of the following hormones declines if pregnancy does not occur?

    <p>LH (C)</p> Signup and view all the answers

    During what phase of the ovarian cycle does the formation of the corpus luteum take place?

    <p>Luteal phase (B)</p> Signup and view all the answers

    What characterizes the myometrium layer of the uterus?

    <p>Three layers of smooth muscle (A)</p> Signup and view all the answers

    Flashcards

    Infundibulum's role in oocyte transport

    The infundibulum, with its fimbriae, sweeps oocytes into the oviduct's opening (ostium).

    Ampulla's function

    The ampulla is the location where fertilization usually occurs.

    Isthmus position in oviduct

    The isthmus forms one-third of the oviduct's length.

    Uterine Tube layers

    The uterine tube has three layers: serosa (outer), smooth muscle layers (middle), and highly folded mucosa lined with ciliated epithelium (inner).

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    Uterine regions

    The uterus has four regions: fundus, body, isthmus, and cervix.

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    Corpora Cavernosa

    Paired erectile tissues located dorsolaterally to the corpora spongiosum.

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    Corpora Spongiosum

    The single erectile tissue that surrounds the urethra, crucial for maintaining the urethra's function during erection.

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    Scrotum function

    Maintains optimal temperature (34°C) for sperm production.

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    Ovarian Follicles

    Structures in the ovary containing developing germ cells (eggs).

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    Theca cells

    Steroidogenic cells that convert cholesterol to androgens.

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    Granulosa cells

    Cells that maintain and mature oocytes, converting androgens to estrogen.

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    Corpus Luteum

    Endocrine organ formed from granulosa and thecal cells and secretes hormones; critical for maintaining pregnancy.

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    Corpus albicans

    Structure that replaces the corpus luteum if pregnancy doesn't occur and is resorbed.

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    Uterine Ducts

    Structures that carry eggs from the ovary to the uterus.

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    Ovarian Arteries/Veins

    Blood vessels supplying and draining the ovary.

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    Ovarian Hilum

    Area where blood vessels and nerves enter or exit the ovary.

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    Zona Pellucida

    Protective layer surrounding the oocyte.

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    Tertiary follicle

    Mature follicle containing fluids and mature egg.

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    Ejaculatory pathway

    The route of sperm and seminal fluid during ejaculation.

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    Spermatogenesis

    The process of sperm production.

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    Adrenarche

    The stage of puberty where the adrenal cortex increases androgen production, typically starting around age 6-8.

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    Gonadarche

    The stage of puberty where gonads mature, enabling them to produce gametes and steroids.

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    Male Gonadarche Hormones

    During male gonadarche, the primary hormone produced is testosterone.

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    Female Gonadarche Hormones

    During female gonadarche, the primary hormones produced are estrogen and progesterone, along with growth hormone, insulin, and thyroid hormones.

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    What is the climacteric?

    The climacteric is the transitional period in both males and females where reproductive years end.

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    Cervix function

    Receives, retains, and nourishes the developing fetus during gestation.

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    Uterine layers

    The uterus has three main layers: perimetrium (outer serosa), myometrium (muscle layers), and endometrium (lining).

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    Endometrium layers

    The endometrium has two layers: the basal layer (permanent, with glands) and the functional layer (hormone-responsive) which grows and is shed during periods.

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    Vagina function

    The vagina is the copulatory organ, birth canal, and passageway for menstrual flow.

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    Vagina layers

    The vagina consists of three layers: outer adventitia, middle muscularis, and inner mucosa.

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    Female External Genitalia

    Includes structures like the mons pubis, labia majora, labia minora, and the clitoris.

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    Female Vestibule

    The area between the labia minora, containing the vaginal opening and ducts of glands.

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    Clitoris Function

    It is an erectile body homologous to the penis, rich in nerve endings, and important in sexual pleasure.

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    Hypothalamic-Pituitary-Gonadal Axis

    Hormonal control system regulating gametogenesis and steroid production in both sexes.

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    GnRH

    Hormone released by the hypothalamus, stimulating the release of LH and FSH.

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    Follicular phase

    Phase of the ovarian cycle, where a follicle matures in preparation for ovulation.

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    Luteal phase

    The phase after ovulation where the corpus luteum forms and produces progesterone in preparation for pregnancy.

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    Menstrual Cycle

    Recurring cycle of changes in the ovaries and uterus to prepare for potential pregnancy.

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    Puberty

    Biological process of becoming sexually mature.

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    Primordial Gonad potential

    Gonads in an embryo have the potential to develop into either ovaries or testes depending on genetic factors.

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    Gametogenesis

    The process of producing gametes (sperm and egg cells).

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    Oogenesis

    The production of eggs (ova) in females.

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    Primordial Germ Cells (PGCs)

    The earliest precursor cells that will develop into sperm or egg cells.

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    What is the role of Sertoli cells?

    Sertoli cells are responsible for supporting and nourishing developing sperm cells in the seminiferous tubules. They also contribute to the seminiferous fluid.

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    Seminiferous Tubules

    Tubules within the testes where sperm cells are produced.

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    Epididymis

    A coiled tube that connects the seminiferous tubules to the vas deferens. It stores and matures sperm.

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    Ductus Deferens (Vas Deferens)

    A tube that carries sperm from the epididymis to the ejaculatory duct.

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    Seminal Vesicles

    Glands that produce a fluid rich in fructose and other substances to provide energy and nourishment to sperm.

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    Prostate Gland

    A gland that produces a fluid that helps to activate sperm and protects it from the acidic environment of the vagina.

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    Bulbourethral Glands

    Glands that produce a clear, alkaline fluid that lubricates the urethra and neutralizes any remaining acidic urine.

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    Penis Anatomy

    The male external genitalia, composed of erectile tissue, urethra, and glans penis.

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    What is the function of the scrotum?

    The scrotum is a pouch that hangs outside the body to regulate the temperature of the testes for optimal sperm production.

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    Menopause

    The cessation of menstruation in women, marking the end of reproductive years.

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    Study Notes

    Reproductive System Overview

    • The reproductive system is a fundamental characteristic of life, responsible for creating new individuals.
    • Sex differentiates biological characteristics, defined by genotype or phenotype.
    • Gender differentiates masculinity and femininity.
    • Gametes are reproductive cells (sperm and egg).

    Gametogenesis

    • Gametogenesis is the production of gametes.
    • Females produce ova (takes 300 days).
    • Males produce sperm (takes 74 days).
    • Gametogenesis begins around the fifth week of embryonic development.
    • Primordial germ cells (PGCs) migrate to genital ridges.
    • PGCs divide mitotically during migration and differentiate into gametes.

    Spermatogenesis

    • Spermatogenesis occurs from puberty onward.
    • Stem cells undergo mitosis to maintain stem cells and type B spermatogonia.
    • Type B spermatogonia undergo further mitosis to double germ cells entering the next step.
    • There are meiotic divisions followed by organelle and cytoplasm modifications which leads to the formation of spermatozoa.
    • The spermatogenic cycle approximately takes 74 days.
    • The entire testis produces millions of spermatogonia.

    Spermatozoon Anatomy

    • Spermatozoa are the only self-propelled swimming cells in the human body.
    • They consist of a head, mid-piece, and tail.
    • The head includes the nucleus and acrosome.
    • The mid-piece contains mitochondria for energy.
    • The tail contains microtubules for movement.

    Oogenesis

    • Oogenesis begins during embryogenesis and continues at puberty.
    • Oogenesis produces an ovum.
    • It starts with oogonia during embryonic development resulting in a population of about ~7 million cells.
    • Most of the oogonia undergo atresia (destruction).
    • About 600,000 remain at puberty and only about 400 will be ovulated throughout a woman's reproductive life.
    • The oocyte undergoes two meiotic divisions with incomplete cytokinesis.
    • Secondary meiotic division occurs with a male gamete present for fertilization.
    • First meiotic division(MI) creates a primary oocyte, and the second meiotic division (MII) creates the secondary oocyte. These processes produce haploid nuclei with very little cytoplasm.

    Male Reproductive Tract

    • The male reproductive tract includes the testes, accessory glands, and ducts.
    • The testes are paired ovoid gonads housed in the scrotum. They divide into 200-300 distinct tubules.
    • The tunica albuginea surrounds the testes.
    • Seminiferous tubules are formed by interconnected Sertoli cells.
    • Sertoli cells direct germ cell development, scavenge cell debris, and produce seminiferous fluid.
    • Sertoli cells also produce inhibin, FSH-responsive, and androgen-binding protein (ABP).
    • Developing germ cells travel from spermatogonia through different stages (primary and secondary spermatocytes, spermatids) to reach spermatozoa in the lumen.
    • Epididymis is a coiled tubule where sperm maturation occurs.
    • Ductus deferens is a continuation of the epididymis.
    • Ejaculatory duct joins ducts deferens and urethra
    • Urethra is a tube that serves both urinary and reproductive functions.
    • Accessory glands (seminal vesicles, prostate, and bulbourethral glands) produce seminal fluid which mixes with sperm.

    Male Accessory Glands

    • Seminal vesicles produce secretions rich in nutrients that provide energy and motility for the sperm.
    • The prostate gland secretes a fluid that aids in sperm motility and viability.
    • The bulbourethral glands produce a pre-ejaculate fluid that lubricates the urethra and neutralizes any residual urine.

    Male External Genitalia

    • The penis is the male external genitalia responsible for sexual intercourse.
    • The penis is composed of the root, body, and glans. The body contains corpora cavernosa and corpora spongiosum containing penile urethra.
    • The glans is the cone-shaped end of the penis
    • The scrotum is a pouch of skin that encloses the testes. It helps regulate testicular temperature.

    Female Reproductive Tract

    • Ovaries are paired organs that produce ova and sex hormones. Ovaries are anchored to the uterus by the mesovarium.
    • Female reproductive tract consists of the ovaries, uterine tubes, uterus, and vagina, external genitalia.
    • Ovarian follicles develop oocytes.
    • A developing follicle forms the primary, secondary, and tertiary follicle, and ovulation occurs once the egg is released in a mature follicle.
    • Corpus luteum (formed from granulosa and thecal cells) is formed after ovulation.
    • If no pregnancy occurs, the corpus luteum regresses to form the corpus albicans.
    • Uterine tubes (fallopian tubes) are the tubes that connect the ovaries to the uterus where fertilization occurs. The uterine tubes have an infundibulum, ampulla, isthmus and intramural segment.

    Female External Genitalia

    • The vulva is the collective term for female external genitalia.
    • It includes the mons pubis, labia majora, labia minora, vestibule, vaginal orifice and clitoris.
    • The clitoris is an erectile body homologous to the male penis, containing corpus cavernosa.
    • The vestibule is the region between the labia minora containing the openings of the urethra and vagina.

    Hormonal Regulation

    • Gametogenesis is regulated by the hypothalamic-pituitary-gonadal (HPG) axis.
    • GnRH from the hypothalamus stimulates the anterior pituitary to release LH and FSH, which stimulate gamete and steroid production in the gonads.
    • Steroid hormones (estrogen, progesterone, testosterone) regulate the menstrual cycle and other reproductive functions.

    Menstrual Cycle

    • The menstrual cycle is a monthly series of changes in the female reproductive system.
    • It involves two intertwined cycles: the ovarian cycle, concerned with follicle development, and the uterine cycle, concerned with changes to the endometrium.
    • The ovarian cycle has a follicular phase (follicle growth), ovulation (release of the egg), and a luteal phase (corpus luteum formation and regrowth of uterine lining).
    • The uterine cycle has 3 phases: menstrual, proliferative, and secretory. These reflect cyclic changes to the lining of the uterus.

    Puberty

    • Puberty is the period of sexual maturation that marks the transition from childhood to adulthood.
    • During puberty, there's an increase in the production of sex hormones (testosterone in males and estrogen and progesterone in females). This results in the development of secondary sexual characteristics and the initiation of gametogenesis.

    Reproductive System Aging

    • Reproductive abilities decline with age.
    • Climacteric in females is associated with a drop in estrogen leading to menopause.
    • Menopause is characterized by the loss of ovarian follicles and the cessation of menstruation.
    • Similar effects occur in males as testosterone production decreases which leads to andropause. Various changes also occur in the male reproductive system such as decreased sperm count, reduced libido and erectile dysfunction.

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    Description

    Explore the essential concepts of the reproductive system in this quiz. Learn about gametogenesis, spermatogenesis, and the differences between biological sex and gender. This quiz covers the development of reproductive cells and their significance in creating new life.

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