Chapter 23 | Male Reproductive

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Questions and Answers

What is the main function of the male gonads in the reproductive system?

  • Production of germ cells (correct)
  • Secretion of estrogen
  • Production of sex hormones
  • Development of secondary sex characteristics

Which hormone is predominantly secreted by the testes in males?

  • Estrogen
  • Testosterone (correct)
  • Inhibins
  • Androgens

How does male gonadotropin secretion differ from females?

  • Increases with age
  • Noncyclical in nature (correct)
  • Inhibited by testosterone
  • Cyclical in nature

What happens to male gonadal function with advancing age?

<p>Slowly declines (C)</p> Signup and view all the answers

In terms of DNA, what is the main source from the male reproductive system?

<p>Testes (D)</p> Signup and view all the answers

Which hormone is masculinizing in its action in males?

<p>Testosterone (C)</p> Signup and view all the answers

What is the role of olfactory receptors in spermatozoa?

<p>Aiding in chemotaxis towards the ovary (D)</p> Signup and view all the answers

What is the function of P2X receptors in male ejaculation?

<p>Mediate contractions of the vas deferens (D)</p> Signup and view all the answers

Where do spermatozoa slow down and undergo capacitation?

<p>Isthmus of the uterine tubes (C)</p> Signup and view all the answers

What is the significance of maintaining testes at a lower temperature?

<p>Facilitates spermatogenesis (C)</p> Signup and view all the answers

What are the ligand gated cation channels that respond to ATP in male ejaculation?

<p>P2X receptors (C)</p> Signup and view all the answers

What is the main nutritional supply for spermatozoa?

<p>Sugar (A)</p> Signup and view all the answers

Where is the temperature of the testes normally maintained?

<p>~32°C (D)</p> Signup and view all the answers

Which hormone causes an increase in body hair but a decrease in scalp hair?

<p>DHT (D)</p> Signup and view all the answers

What is responsible for the fusion of epiphyses to the long bones?

<p>Estrogens (C)</p> Signup and view all the answers

What process results from testosterone binding to an intracellular receptor?

<p>Transcription of genes (B)</p> Signup and view all the answers

Which hormone limits the usefulness of testosterone as an anabolic agent in patients with wasting diseases?

<p>Libido (D)</p> Signup and view all the answers

What enzyme converts testosterone to DHT in some target cells?

<p>5α-reductase (B)</p> Signup and view all the answers

What is the role of androgen in the maturation of spermatids to spermatozoa?

<p>Activating Sertoli cells (C)</p> Signup and view all the answers

Which hormone acts on Sertoli cells to promote the last stages of spermatid maturation?

<p>FSH (D)</p> Signup and view all the answers

Where do spermatozoa acquire motility during their development?

<p>Epididymis (A)</p> Signup and view all the answers

What is the importance of motility for spermatozoa in vivo?

<p>To enable them to move forward towards the ova (A)</p> Signup and view all the answers

What proteins are responsible for the acquired motility of spermatozoa in the epididymis?

<p>CatSper family proteins (D)</p> Signup and view all the answers

What happens to sperm from knockout mice that do not express CatSper1-4?

<p>They have altered motility and are infertile (B)</p> Signup and view all the answers

What is the role of FSH in the male reproductive system?

<p>Maintains gametogenic function of the testes (A)</p> Signup and view all the answers

How does LH affect Leydig cells?

<p>Stimulates testosterone secretion (A)</p> Signup and view all the answers

What feedback mechanism does testosterone have on LH secretion?

<p>Inhibits LH secretion (A)</p> Signup and view all the answers

What is the impact of hypothalamic lesions on testicular function?

<p>Leads to testicular atrophy (C)</p> Signup and view all the answers

What is the role of inhibin in the male reproductive system?

<p>Stimulates FSH secretion (B)</p> Signup and view all the answers

What are the subunits that form inhibins in the male reproductive system?

<p>βA and βB subunits (C)</p> Signup and view all the answers

What is the function of the blood-testis barrier described in the passage?

<p>Allows germ cells to remain in contact with Sertoli cells for survival (B)</p> Signup and view all the answers

Which cell type forms cytoplasmic bridges with germ cells to ensure their survival?

<p>Sertoli cells (A)</p> Signup and view all the answers

What is the role of tight junctions between adjacent Sertoli cells near the basal lamina?

<p>Create a barrier that prevents movement of large molecules from the interstitial tissue to the tubular lumen (B)</p> Signup and view all the answers

What is the role of NO in the male reproductive system?

<p>Promoting erection (B)</p> Signup and view all the answers

What is one of the functions attributed to the paracrine activity between Sertoli and Leydig cells?

<p>Promotes maturation of spermatozoa (A)</p> Signup and view all the answers

How is erection terminated in the male reproductive system?

<p>Sympathetic vasoconstrictor impulses (A)</p> Signup and view all the answers

How do maturing germ cells navigate through the blood-testis barrier?

<p>By undergoing coordinated breakdown of tight junctions above them (D)</p> Signup and view all the answers

What initiates the process of ejaculation in males?

<p>Touch receptors in the glans penis (B)</p> Signup and view all the answers

What is the significance of germ cells needing to stay in contact with Sertoli cells?

<p>To ensure survival and proper development (B)</p> Signup and view all the answers

Which neurotransmitter is likely released by efferent parasympathetic fibers in the male reproductive system?

<p>Vasoactive intestinal polypeptide (VIP) (B)</p> Signup and view all the answers

What is the main effect of androgens on protein synthesis and breakdown?

<p>Increase synthesis and decrease breakdown (B)</p> Signup and view all the answers

What is the enzyme responsible for converting testosterone to DHT in some target cells?

<p>5α-reductase (A)</p> Signup and view all the answers

What is the effect of dihydrotestosterone (DHT) on hereditary baldness development?

<p>Prevents baldness development (A)</p> Signup and view all the answers

How do androgens impact the fusion of epiphyses to long bones?

<p>Cause fusion of epiphyses (B)</p> Signup and view all the answers

What limits the usefulness of exogenous testosterone as an anabolic agent in patients with wasting diseases?

<p>Masculinizing effects (C)</p> Signup and view all the answers

Which ion retention is caused by androgens due to their anabolic effects?

<p>K+ (A)</p> Signup and view all the answers

What is the final stage of maturation for spermatids to become motile spermatozoa?

<p>Spermiogenesis (B)</p> Signup and view all the answers

Which hormone is the principal hormone of the testis and plays a key role in the development of male secondary sex characteristics?

<p>Testosterone (B)</p> Signup and view all the answers

What is the rate at which testosterone is synthesized by Leydig cells under the control of luteinizing hormone in adult males?

<p>4–9 mg/day (D)</p> Signup and view all the answers

Where is most of the testosterone found in the plasma after being synthesized?

<p>Bound to albumin (B)</p> Signup and view all the answers

What type of cell division occurs from a spermatogonium to a spermatid?

<p>Incomplete division (C)</p> Signup and view all the answers

What is the primary function of inhibin B in adult men and women?

<p>Inhibit FSH secretion (B)</p> Signup and view all the answers

Where are inhibins and activins primarily produced in males and females?

<p>Gonads (B)</p> Signup and view all the answers

What is the function of activins in the bone marrow?

<p>Facilitate white blood cell development (A)</p> Signup and view all the answers

How does castration impact FSH and LH secretion?

<p>Increases both FSH and LH secretion (B)</p> Signup and view all the answers

In the male reproductive system, what is the direct effect of inhibin on the anterior pituitary?

<p>Inhibits FSH secretion (C)</p> Signup and view all the answers

What is the role of the heterodimer βAβB in the male reproductive system?

<p>Promote FSH secretion (D)</p> Signup and view all the answers

What is the final stage of maturation for spermatids?

<p>Spermiogenesis (A)</p> Signup and view all the answers

Where is testosterone synthesized in the male reproductive system?

<p>Leydig cells (B)</p> Signup and view all the answers

What is the principal hormone of the testis?

<p>Testosterone (B)</p> Signup and view all the answers

Which hormone controls the secretion of testosterone from Leydig cells?

<p>Luteinizing hormone (LH) (A)</p> Signup and view all the answers

What is the main function of testosterone in the male reproductive system?

<p>Development of male secondary sex characteristics (B)</p> Signup and view all the answers

How is testosterone primarily transported in the plasma?

<p>Bound to albumin (D)</p> Signup and view all the answers

At what rate is testosterone synthesized by Leydig cells in adult males?

<p>$4-9$ mg/day (C)</p> Signup and view all the answers

What type of cell division occurs from a spermatogonium to a spermatid?

<p>Incomplete division (C)</p> Signup and view all the answers

What is the role of testosterone in spermatogenesis?

<p>Maintains male secondary sex characteristics (A)</p> Signup and view all the answers

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