Podcast
Questions and Answers
Which hormone is primarily responsible for initiating uterine contractions during labor?
Which hormone is primarily responsible for initiating uterine contractions during labor?
What is the main component of amniotic fluid?
What is the main component of amniotic fluid?
What does green-tinged amniotic fluid typically indicate?
What does green-tinged amniotic fluid typically indicate?
How does the mother contribute to the amniotic fluid volume?
How does the mother contribute to the amniotic fluid volume?
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Which of the following functions is NOT performed by amniotic fluid?
Which of the following functions is NOT performed by amniotic fluid?
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At what location does fertilization typically occur?
At what location does fertilization typically occur?
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What is the primary function of the trophoblast during the development of the blastocyst?
What is the primary function of the trophoblast during the development of the blastocyst?
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Which structure plays a crucial role in preventing infection from reaching the fetus post-implantation?
Which structure plays a crucial role in preventing infection from reaching the fetus post-implantation?
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What happens during the process of polyspermy?
What happens during the process of polyspermy?
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Which type of gamete has a lifespan of 24 hours within the female reproductive system?
Which type of gamete has a lifespan of 24 hours within the female reproductive system?
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Study Notes
Ovum
- The female egg cell, known as the ovum, is the female gamete
- It has two layers:
- The outer layer is called the corona radiata
- The inner layer is called the zona pellucida
- It has a lifespan of 24 hours
Sperm Cell
- Sperm cells are the male gametes
- They are also known as spermatozoa
- They have three parts:
- The head contains chromatin material
- The neck or mid-piece provides energy for movement
- The tail is responsible for motility
- They have a lifespan of 48 to 72 hours (2-3 days) after ejaculation
- There are two kinds of sperm cells:
- Gynosperm carries the X chromosome
- Androsperm carries the Y chromosome
Insemination
- Fertilization is when the sperm and ovum unite, creating a fertilized ovum called a zygote
- This occurs in the outer third portion of the fallopian tube
- The process involves:
- Penetration
- Mitotic cellular division
- Chromosomal formation
- Capacitation
- Hyaluronidase
- Acrosin
- Polyspermy occurs when more than one sperm cell enters the ovum
Zygote
- The zygote travels from the fallopian tube to the uterus over 3-4 days
- Zygotes can divide and create many daughter cells called blastomeres
- A zygote with multiple blastomeres is called a morula
Blastocyst
- The blastocyst contains two parts:
- An inner layer called the blastocele
- An outer layer called the trophoblast or trophoderm
- The blastocele contains the following layers:
- Ectoderm
- Entoderm
- Mesoderm
- The trophoblast is responsible for:
- Absorbing nutrients from the endometrium
- Secreting the hormone human chorionic gonadotropin (hCG) which keeps the corpus luteum alive and pumping out hormones
Implantation
- Occurs 6 to 7 days after fertilization
- Implantation bleeding may occur
Decidua
- Refers to the endometrium after implantation
- It functions as:
- The ideal site for implantation
- Provides easy access for the baby's birth at the end of gestation
- Prevents infection from the vagina and cervix
- The decidua produces the following hormones:
- Prolactin
- Relaxin
- Corticotrophin Releasing Hormone (CRH)
- Growth Hormones
- Prostaglandin
- Oxytocin
- Endothelin-I
Fetal Membranes
- Enclose the fetus and amniotic fluid
- There are two membranes:
- Chorionic membrane - The outermost layer that separates the baby's amniotic sac from the wall of the uterus
- Amniotic membrane - The amniotic sac
Amniotic Fluid
- The medium in which the fetus and cord float inside the amniotic membrane
- The fetus contributes to amniotic fluid by:
- Active secretion from the epithelium of the amniotic membrane
- Transudation
- Fetal urination
- The mother contributes to amniotic fluid by:
- Transudation from maternal circulation
Amniotic Fluid Removal
- Amniotic fluid is removed or absorbed by:
- Absorption through the amnion to the maternal circulation
- Fetal swallowing, this is the main mechanism that controls amniotic fluid volume
Amniotic Fluid Characteristics
- Normal volume is 500 to 1200 ml, averaging 1000 ml
- Composition: 99% water and 1% solid particles
- Contains albumin, urea, uric acid, creatinine, lecithin, sphingomyelin, bilirubin, minerals, and suspended materials like desquamated epithelial cells and vernix caseosa
- Color is clear and odorless to straw-colored
- Green tinged or meconium stained can signify fetal distress
- Golden colored amniotic fluid can signify hemolytic disease
- Gray colored amniotic fluid can signify infection
- Bloody amniotic fluid can signify vasa previa
- Brownish, coffee or tea-colored amniotic fluid can signify fetal death
- pH is 7.0 to 7.25, a normal to alkaline reaction
- Specific Gravity - 1.005 to 1.025
Amniotic Fluid Functions
- Protection of the fetus:
- From trauma, blows, and pressure
- From uterine contractions
- From sudden changes in temperature
- Of the cord from pressure
- Promotes symmetrical musculoskeletal development by allowing freedom of movement
- Acts as an excretion and secretion system
- Source of oral fluid for the fetus who swallows it
- Aids in the diagnosis of maternal and fetal complications through amniocentesis
- Assists in labor by:
- Intact membranes aid in effacement and dilation of the cervix
- Once membranes rupture, the fluid washes the birth canal and serves as an antiseptic
- It acts as a lubricant, making the birth canal more slippery for passage of the fetus
Umbilical Cord or Funis
- Function: Connection between the fetus and placenta
- Main function: Transport oxygen and nutrients from the placenta to the fetus, and return unoxygenated blood and fetal waste products to the placenta
- Blood vessels: Two arteries and one vein
- Length: About 50-55 cm long and 2 cm in diameter
- Appearance: Dull white and covered by amnion
Umbilical Cord Abnormalities - Short Cord
- Short cord can lead to:
- Intrapartum hemorrhage due to premature separation of the placenta
- Delayed descent of the fetus during labor
- Inversion of the uterus
Umbilical Cord Abnormalities - Long Cord
- Long cord can lead to:
- Wrap around the baby’s neck or body
- Prolapse of the cord before the baby is born
- A knot in the cord that could cut off the baby's blood supply
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Description
Test your knowledge on the fundamentals of reproductive biology, including the structures and functions of ovum and sperm cells, as well as the process of insemination and fertilization. Explore the key concepts related to female and male gametes and their roles in human reproduction.