10 Questions
What is the primary function of renin in the renin-angiotensin-aldosterone system?
To convert angiotensinogen into angiotensin I
Glucose-6-phosphatase is primarily involved in which of the following processes?
Maintenance of interprandial glucose homeostasis
Which of the following is a clinical significance of glucose-6-phosphatase?
Glycogen storage disease type I (von Gierke's disease)
What is the function of kallikrein in the kidneys?
To inhibit the reabsorption of NaCl
Which of the following enzymes is primarily involved in the regulation of blood pressure?
Renin
What is the primary function of the renal kallikrein-kinin system within the nephrons of the kidney?
To inhibit the reabsorption of NaCl
Which enzyme is involved in the synthesis of the active form of vitamin D?
25 1α-Hydroxylase
What is the clinical significance of 11β-hydroxysteroid dehydrogenase type 2 deficiency?
Apparent mineralocorticoid excess (AME)
In which tissues is 11β-hydroxysteroid dehydrogenase type 1 highly expressed?
Liver, adipose tissue, and the central nervous system
What is the role of tissue kallikrein/kinin in the kidney?
To regulate renal blood flow and modulate tubular salt and water transport
Test your knowledge of the functions and locations of renin and glucose-6-phosphatase, and their importance in regulating blood pressure, aldosterone production, and Na/K levels. Learn about their roles in kidney and heart failure, and diabetes. Assess your understanding of these biological enzymes.
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