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Renin and Glucose-6-Phosphatase Functions

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Renin and Glucose-6-Phosphatase Functions

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Questions and Answers

What is the primary function of renin in the renin-angiotensin-aldosterone system?

To regulate Na/K levels

To convert angiotensinogen into angiotensin I (correct)

To convert angiotensin I into angiotensin II

To stimulate the release of aldosterone

Glucose-6-phosphatase is primarily involved in which of the following processes?

Reabsorption of NaCl in the kidneys

Regulation of blood pressure

Maintenance of interprandial glucose homeostasis (correct)

Stimulation of aldosterone production

Which of the following is a clinical significance of glucose-6-phosphatase?

Maintenance of glycogen storage

Regulation of Na/K levels

Glycogen storage disease type I (von Gierke's disease) (correct)

Diagnosis of kidney and heart failure

What is the function of kallikrein in the kidneys?

To inhibit the reabsorption of NaCl Signup and view all the answers

Which of the following enzymes is primarily involved in the regulation of blood pressure?

Renin Signup and view all the answers

What is the primary function of the renal kallikrein-kinin system within the nephrons of the kidney?

To inhibit the reabsorption of NaCl Signup and view all the answers

Which enzyme is involved in the synthesis of the active form of vitamin D?

25 1α-Hydroxylase Signup and view all the answers

What is the clinical significance of 11β-hydroxysteroid dehydrogenase type 2 deficiency?

Apparent mineralocorticoid excess (AME) Signup and view all the answers

In which tissues is 11β-hydroxysteroid dehydrogenase type 1 highly expressed?

Liver, adipose tissue, and the central nervous system Signup and view all the answers

What is the role of tissue kallikrein/kinin in the kidney?

To regulate renal blood flow and modulate tubular salt and water transport Signup and view all the answers