Renal Tubules and Interstitium Disorders Quiz
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Questions and Answers

Which of the following is NOT a type of cast seen in the urine?

  • Hyaline cast
  • Renal artery stenosis cast (correct)
  • Waxy cast
  • Red blood cell cast
  • Which of the following conditions involves inflammation of the interstitium surrounding the nephrons?

  • Nephritic syndrome
  • Horseshoe kidney
  • Tubulointerstitial nephritis (correct)
  • Acute tubular necrosis
  • What is the preferred term for acute kidney injury with morphologic evidence of tubular damage, but without necrosis?

  • Acute tubular injury (correct)
  • Renal artery stenosis
  • Acute tubular necrosis
  • Nephritic syndrome
  • Which of the following is a congenital abnormality of the kidneys?

    <p>Horseshoe kidney</p> Signup and view all the answers

    Which of the following is a disorder characterized by inflammation of the glomeruli?

    <p>Nephritic syndrome</p> Signup and view all the answers

    What is the most common cause of acute kidney injury, according to the text?

    <p>Acute tubular injury/necrosis</p> Signup and view all the answers

    Which of the following is a characteristic of renal artery stenosis?

    <p>All of the above</p> Signup and view all the answers

    What is the staging system used to classify chronic kidney disease (CKD)?

    <p>All of the above</p> Signup and view all the answers

    Which of the following is a characteristic of a horseshoe kidney?

    <p>The two kidneys are fused at the lower poles</p> Signup and view all the answers

    What is the primary characteristic of nephritic syndrome?

    <p>Hematuria</p> Signup and view all the answers

    Which part of the nephron is responsible for the initial filtration of blood?

    <p>Glomerulus</p> Signup and view all the answers

    What is the primary function of the medulla in the kidney?

    <p>Reabsorption of water and solutes</p> Signup and view all the answers

    What is the most likely cause of the 58-year-old man's presentation with decreased urine output and increased BUN after being discharged from the hospital for acute myocardial infarction?

    <p>Acute tubular necrosis</p> Signup and view all the answers

    What is the primary composition of calcium stones, which make up 70% of renal stones?

    <p>Calcium oxalate or calcium phosphate</p> Signup and view all the answers

    Which type of stone is composed largely of magnesium ammonium phosphate?

    <p>Struvite stones</p> Signup and view all the answers

    The main factor contributing to the initiation and propagation of renal stones is:

    <p>Raised urinary concentrations exceeding solubility limits</p> Signup and view all the answers

    What is the most common cause of nephrotic syndrome in adults?

    <p>Focal segmental glomerulosclerosis</p> Signup and view all the answers

    Which of the following is a characteristic of membranous nephropathy?

    <p>Diffuse thickening of the glomerular basement membrane</p> Signup and view all the answers

    Which of the following is a common complication of nephrotic syndrome?

    <p>Increased risk of infection</p> Signup and view all the answers

    What is the primary cause of nephrotic syndrome?

    <p>Derangement in glomerular capillary walls</p> Signup and view all the answers

    Which of the following is a characteristic of minimal change disease?

    <p>Effacement of podocyte foot processes</p> Signup and view all the answers

    What is the most common cause of nephrotic syndrome in children?

    <p>Minimal change disease</p> Signup and view all the answers

    What is the most common cause of nephrotic syndrome mentioned in the text?

    <p>Diabetic nephropathy</p> Signup and view all the answers

    Which type of Membranoproliferative Glomerulonephritis (MPGN) is characterized by activation of the complement system?

    <p>Type II MPGN (dense deposit disease)</p> Signup and view all the answers

    What is the prognosis for patients with Membranoproliferative Glomerulonephritis (MPGN)?

    <p>Poor, with 50% of patients developing end-stage renal disease</p> Signup and view all the answers

    What is the most common clinical presentation of Membranoproliferative Glomerulonephritis (MPGN)?

    <p>Nephrotic-nephritic picture with hematuria or proteinuria in the non-nephrotic range</p> Signup and view all the answers

    Which histological feature is characteristic of Membranoproliferative Glomerulonephritis (MPGN)?

    <p>Proliferation of glomerular cells and accumulation of mesangial matrix</p> Signup and view all the answers

    Which type of Membranoproliferative Glomerulonephritis (MPGN) is characterized by the deposition of immune complexes containing IgG and complement?

    <p>Type I MPGN</p> Signup and view all the answers

    Which type of immune complex deposition within the glomerulus is associated with the nephrotic syndrome?

    <p>Membranous deposits</p> Signup and view all the answers

    What is the primary pathological change seen in the nephritic syndrome?

    <p>Swelling and proliferation of endothelial cells</p> Signup and view all the answers

    Which of the following is a potential outcome of glomerulonephritis?

    <p>All of the above</p> Signup and view all the answers

    What is the primary cause of the swelling and proliferation of endothelial cells seen in glomerulonephritis?

    <p>Deposition of immune complexes</p> Signup and view all the answers

    Which type of glomerulonephritis is characterized by the formation of crescents in the Bowman's capsule?

    <p>Rapidly progressive glomerulonephritis</p> Signup and view all the answers

    What is the primary characteristic of the nephrotic syndrome?

    <p>Heavy proteinuria</p> Signup and view all the answers

    What type of cells are seen in chronic pyelonephritis?

    <p>Lymphocytes</p> Signup and view all the answers

    Which part of the kidney shows atrophic tubules with flattened epithelium in chronic pyelonephritis?

    <p>Cortex</p> Signup and view all the answers

    What is the distinguishing feature of glomerulonephritis compared to chronic pyelonephritis?

    <p>Hyaline casts in urine</p> Signup and view all the answers

    Which renal disorder is associated with squamous metaplasia of the transitional epithelium in the renal pelvis?

    <p>Pyelonephritis</p> Signup and view all the answers

    Which condition is characterized by shrunken kidneys and irregular scarring upon autopsy?

    <p><strong>Nephrosclerosis</strong></p> Signup and view all the answers

    What is the most likely cause of renal failure in the presented case?

    <p><strong>Chronic Glomerulonephritis</strong></p> Signup and view all the answers

    Which of the following is a characteristic feature of nephritic syndrome?

    <p>Haematuria and proteinuria</p> Signup and view all the answers

    What is the most common cause of acute proliferative glomerulonephritis?

    <p>Post-streptococcal infection</p> Signup and view all the answers

    Which of the following is NOT a characteristic feature of rapidly progressive glomerulonephritis (RPGN)?

    <p>Specific aetiology</p> Signup and view all the answers

    In which condition is the inciting antigen endogenous?

    <p>Lupus nephritis</p> Signup and view all the answers

    What is the typical outcome of post-streptococcal glomerulonephritis in children with conservative therapy?

    <p>95% recover fully</p> Signup and view all the answers

    Which condition presents similarly to post-streptococcal glomerulonephritis but is differentiated by the presence of IgA deposits in the glomeruli?

    <p>IgA nephropathy</p> Signup and view all the answers

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