Renal Tubules and Interstitium Disorders Quiz
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Questions and Answers

Which of the following is NOT a type of cast seen in the urine?

  • Hyaline cast
  • Renal artery stenosis cast (correct)
  • Waxy cast
  • Red blood cell cast

Which of the following conditions involves inflammation of the interstitium surrounding the nephrons?

  • Nephritic syndrome
  • Horseshoe kidney
  • Tubulointerstitial nephritis (correct)
  • Acute tubular necrosis

What is the preferred term for acute kidney injury with morphologic evidence of tubular damage, but without necrosis?

  • Acute tubular injury (correct)
  • Renal artery stenosis
  • Acute tubular necrosis
  • Nephritic syndrome

Which of the following is a congenital abnormality of the kidneys?

<p>Horseshoe kidney (D)</p> Signup and view all the answers

Which of the following is a disorder characterized by inflammation of the glomeruli?

<p>Nephritic syndrome (C)</p> Signup and view all the answers

What is the most common cause of acute kidney injury, according to the text?

<p>Acute tubular injury/necrosis (C)</p> Signup and view all the answers

Which of the following is a characteristic of renal artery stenosis?

<p>All of the above (D)</p> Signup and view all the answers

What is the staging system used to classify chronic kidney disease (CKD)?

<p>All of the above (D)</p> Signup and view all the answers

Which of the following is a characteristic of a horseshoe kidney?

<p>The two kidneys are fused at the lower poles (A)</p> Signup and view all the answers

What is the primary characteristic of nephritic syndrome?

<p>Hematuria (D)</p> Signup and view all the answers

Which part of the nephron is responsible for the initial filtration of blood?

<p>Glomerulus (D)</p> Signup and view all the answers

What is the primary function of the medulla in the kidney?

<p>Reabsorption of water and solutes (A)</p> Signup and view all the answers

What is the most likely cause of the 58-year-old man's presentation with decreased urine output and increased BUN after being discharged from the hospital for acute myocardial infarction?

<p>Acute tubular necrosis (D)</p> Signup and view all the answers

What is the primary composition of calcium stones, which make up 70% of renal stones?

<p>Calcium oxalate or calcium phosphate (D)</p> Signup and view all the answers

Which type of stone is composed largely of magnesium ammonium phosphate?

<p>Struvite stones (B)</p> Signup and view all the answers

The main factor contributing to the initiation and propagation of renal stones is:

<p>Raised urinary concentrations exceeding solubility limits (D)</p> Signup and view all the answers

What is the most common cause of nephrotic syndrome in adults?

<p>Focal segmental glomerulosclerosis (A)</p> Signup and view all the answers

Which of the following is a characteristic of membranous nephropathy?

<p>Diffuse thickening of the glomerular basement membrane (A)</p> Signup and view all the answers

Which of the following is a common complication of nephrotic syndrome?

<p>Increased risk of infection (C)</p> Signup and view all the answers

What is the primary cause of nephrotic syndrome?

<p>Derangement in glomerular capillary walls (C)</p> Signup and view all the answers

Which of the following is a characteristic of minimal change disease?

<p>Effacement of podocyte foot processes (A)</p> Signup and view all the answers

What is the most common cause of nephrotic syndrome in children?

<p>Minimal change disease (C)</p> Signup and view all the answers

What is the most common cause of nephrotic syndrome mentioned in the text?

<p>Diabetic nephropathy (D)</p> Signup and view all the answers

Which type of Membranoproliferative Glomerulonephritis (MPGN) is characterized by activation of the complement system?

<p>Type II MPGN (dense deposit disease) (D)</p> Signup and view all the answers

What is the prognosis for patients with Membranoproliferative Glomerulonephritis (MPGN)?

<p>Poor, with 50% of patients developing end-stage renal disease (A)</p> Signup and view all the answers

What is the most common clinical presentation of Membranoproliferative Glomerulonephritis (MPGN)?

<p>Nephrotic-nephritic picture with hematuria or proteinuria in the non-nephrotic range (A)</p> Signup and view all the answers

Which histological feature is characteristic of Membranoproliferative Glomerulonephritis (MPGN)?

<p>Proliferation of glomerular cells and accumulation of mesangial matrix (A)</p> Signup and view all the answers

Which type of Membranoproliferative Glomerulonephritis (MPGN) is characterized by the deposition of immune complexes containing IgG and complement?

<p>Type I MPGN (C)</p> Signup and view all the answers

Which type of immune complex deposition within the glomerulus is associated with the nephrotic syndrome?

<p>Membranous deposits (C)</p> Signup and view all the answers

What is the primary pathological change seen in the nephritic syndrome?

<p>Swelling and proliferation of endothelial cells (B)</p> Signup and view all the answers

Which of the following is a potential outcome of glomerulonephritis?

<p>All of the above (D)</p> Signup and view all the answers

What is the primary cause of the swelling and proliferation of endothelial cells seen in glomerulonephritis?

<p>Deposition of immune complexes (C)</p> Signup and view all the answers

Which type of glomerulonephritis is characterized by the formation of crescents in the Bowman's capsule?

<p>Rapidly progressive glomerulonephritis (A)</p> Signup and view all the answers

What is the primary characteristic of the nephrotic syndrome?

<p>Heavy proteinuria (A)</p> Signup and view all the answers

What type of cells are seen in chronic pyelonephritis?

<p>Lymphocytes (C)</p> Signup and view all the answers

Which part of the kidney shows atrophic tubules with flattened epithelium in chronic pyelonephritis?

<p>Cortex (B)</p> Signup and view all the answers

What is the distinguishing feature of glomerulonephritis compared to chronic pyelonephritis?

<p>Hyaline casts in urine (C)</p> Signup and view all the answers

Which renal disorder is associated with squamous metaplasia of the transitional epithelium in the renal pelvis?

<p>Pyelonephritis (A)</p> Signup and view all the answers

Which condition is characterized by shrunken kidneys and irregular scarring upon autopsy?

<p><strong>Nephrosclerosis</strong> (A)</p> Signup and view all the answers

What is the most likely cause of renal failure in the presented case?

<p><strong>Chronic Glomerulonephritis</strong> (A)</p> Signup and view all the answers

Which of the following is a characteristic feature of nephritic syndrome?

<p>Haematuria and proteinuria (C)</p> Signup and view all the answers

What is the most common cause of acute proliferative glomerulonephritis?

<p>Post-streptococcal infection (A)</p> Signup and view all the answers

Which of the following is NOT a characteristic feature of rapidly progressive glomerulonephritis (RPGN)?

<p>Specific aetiology (A)</p> Signup and view all the answers

In which condition is the inciting antigen endogenous?

<p>Lupus nephritis (D)</p> Signup and view all the answers

What is the typical outcome of post-streptococcal glomerulonephritis in children with conservative therapy?

<p>95% recover fully (C)</p> Signup and view all the answers

Which condition presents similarly to post-streptococcal glomerulonephritis but is differentiated by the presence of IgA deposits in the glomeruli?

<p>IgA nephropathy (C)</p> Signup and view all the answers

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