Renal Physiology Overview
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Questions and Answers

What is the main reason patients are given Clexane?

  • To increase renal natriuretic peptide production
  • To prevent deep vein thrombosis (correct)
  • To inhibit the release of EPO
  • To stimulate prostaglandin synthesis
  • Which condition can lead to the release of EPO?

  • Hyperglycemia
  • Hypernatremia
  • Hypoxia (correct)
  • Low levels of prostaglandins
  • What is the function of prostaglandins in the kidney?

  • Prevent diuresis
  • Ensure renal blood flow (correct)
  • Cause vasoconstriction
  • Stimulate EPO production
  • Which enzyme is responsible for the production of prostaglandins from arachidonic acid?

    <p>COX-2</p> Signup and view all the answers

    What is the effect of NSAIDs on prostaglandin production in the kidney?

    <p>Block COX enzymes</p> Signup and view all the answers

    Which component produced by the kidney is responsible for causing vasodilatation?

    <p>Prostaglandin H2</p> Signup and view all the answers

    Where does hydroxylation at C1 occur in the process of calcitriol production?

    <p>Kidney</p> Signup and view all the answers

    Which form of Vitamin D is recommended for patients with liver impairment?

    <p>Calcifediol</p> Signup and view all the answers

    What is the description of the anemia that occurs in kidney impairment?

    <p>Normocytic normochromic anemia</p> Signup and view all the answers

    Which cells produce 10% of erythropoietin (EPO)?

    <p>Liver cells</p> Signup and view all the answers

    What causes polycythemia in polycystic renal disease?

    <p>Overproduction of EPO</p> Signup and view all the answers

    Which vitamin D form is used in renal impairment?

    <p>Alfacalcidol</p> Signup and view all the answers

    Which iron compound is composed of iron complexed with carbohydrate polymer derived from dextran?

    <p>Iron dextran</p> Signup and view all the answers

    What is the ideal route for administering EPO to a patient?

    <p>Subcutaneous injection</p> Signup and view all the answers

    What condition can develop in a patient when EPO-α is administered subcutaneously?

    <p>Pure red blood cell aplasia</p> Signup and view all the answers

    What is the target hemoglobin (Hb) level suggested when giving EPO?

    <p>10-12 g/dL</p> Signup and view all the answers

    What effect can EPO have on blood pressure when administered?

    <p>Increase blood pressure</p> Signup and view all the answers

    Which type of EPO is safer to administer subcutaneously compared to the other type when considering allergic reactions?

    <p>EPO-α</p> Signup and view all the answers

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