Renal Physiology Overview

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What is the main reason patients are given Clexane?

To increase renal natriuretic peptide production

To prevent deep vein thrombosis (correct)

To inhibit the release of EPO

To stimulate prostaglandin synthesis

Which condition can lead to the release of EPO?

Hyperglycemia

Hypernatremia

Hypoxia (correct)

Low levels of prostaglandins

What is the function of prostaglandins in the kidney?

Prevent diuresis

Ensure renal blood flow (correct)

Cause vasoconstriction

Stimulate EPO production

Which enzyme is responsible for the production of prostaglandins from arachidonic acid?

COX-2 Signup and view all the answers

What is the effect of NSAIDs on prostaglandin production in the kidney?

Block COX enzymes Signup and view all the answers

Which component produced by the kidney is responsible for causing vasodilatation?

Prostaglandin H2 Signup and view all the answers

Where does hydroxylation at C1 occur in the process of calcitriol production?

Kidney Signup and view all the answers

Which form of Vitamin D is recommended for patients with liver impairment?

Calcifediol Signup and view all the answers

What is the description of the anemia that occurs in kidney impairment?

Normocytic normochromic anemia Signup and view all the answers

Which cells produce 10% of erythropoietin (EPO)?

Liver cells Signup and view all the answers

What causes polycythemia in polycystic renal disease?

Overproduction of EPO Signup and view all the answers

Which vitamin D form is used in renal impairment?

Alfacalcidol Signup and view all the answers

Which iron compound is composed of iron complexed with carbohydrate polymer derived from dextran?

Iron dextran Signup and view all the answers

What is the ideal route for administering EPO to a patient?

Subcutaneous injection Signup and view all the answers

What condition can develop in a patient when EPO-α is administered subcutaneously?

Pure red blood cell aplasia Signup and view all the answers

What is the target hemoglobin (Hb) level suggested when giving EPO?

10-12 g/dL Signup and view all the answers

What effect can EPO have on blood pressure when administered?

Increase blood pressure Signup and view all the answers

Which type of EPO is safer to administer subcutaneously compared to the other type when considering allergic reactions?

EPO-α Signup and view all the answers

Renal Physiology Overview

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Questions and Answers

What is the main reason patients are given Clexane?

Which condition can lead to the release of EPO?

What is the function of prostaglandins in the kidney?

Which enzyme is responsible for the production of prostaglandins from arachidonic acid?

What is the effect of NSAIDs on prostaglandin production in the kidney?

Which component produced by the kidney is responsible for causing vasodilatation?

Where does hydroxylation at C1 occur in the process of calcitriol production?

Which form of Vitamin D is recommended for patients with liver impairment?

What is the description of the anemia that occurs in kidney impairment?

Which cells produce 10% of erythropoietin (EPO)?

What causes polycythemia in polycystic renal disease?

Which vitamin D form is used in renal impairment?

Which iron compound is composed of iron complexed with carbohydrate polymer derived from dextran?

What is the ideal route for administering EPO to a patient?

What condition can develop in a patient when EPO-α is administered subcutaneously?

What is the target hemoglobin (Hb) level suggested when giving EPO?

What effect can EPO have on blood pressure when administered?

Which type of EPO is safer to administer subcutaneously compared to the other type when considering allergic reactions?

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