Renal Function Evaluation Quiz

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Questions and Answers

What does an elevated blood urea nitrogen (BUN) indicate?

  • Decreased glomerular filtration rate (GFR) (correct)
  • Reduced urea production in the liver
  • Low dietary protein intake
  • Normal kidney function

Which factor affects the blood urea nitrogen (BUN) level?

  • Decreased creatinine levels
  • Urea production in the liver
  • Decreased serum phosphorus concentration
  • Gastrointestinal (GI) bleeding (correct)

What does a normal serum creatinine concentration imply?

  • Cachexia
  • Elevated phosphorus concentration
  • Impaired kidney function
  • Normal kidney function (correct)

When is an increase in serum phosphorus concentration typically seen in chronic renal diseases?

<p>When more than 85% of nephrons are non-functional (C)</p>
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What is the effect of cachexia on serum creatinine concentrations?

<p>Reduction (C)</p>
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What is the purpose of renal secondary hyperparathyroidism in relation to serum phosphorus concentration?

<p>To keep the serum phosphorus concentration within normal limits by excreting more phosphorus into the urine (A)</p>
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Why can serum phosphorus concentration be much higher in immature animals?

<p>Due to higher parathyroid hormone levels (C)</p>
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Which biomarker increases earlier than creatinine as glomerular filtration rate decreases?

<p>Symmetric dimethylarginine (D)</p>
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In chronic kidney disease, what is used for staging based on blood creatinine and SDMA concentrations?

<p>Exogenous creatinine clearance (C)</p>
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What does fractional excretion of sodium indicate in the differentiation of prerenal and primary renal azotemia?

<p>Sodium conservation with a very low fractional excretion of sodium in prerenal azotemia (C)</p>
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What is the usefulness of monitoring urinary enzymes for renal tubular damage detection?

<p>Both Υ-glutamyltransferase (GGT) and NAG are specific for renal tubular damage (C)</p>
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What property of urine is typically altered in dogs and may become cloudy?

<p>Appearance due to mucus or casts (C)</p>
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What causes urine to have a red or reddish-brown color?

<p>Intact redblood cells (RBCs), hemoglobin, or myoglobin (A)</p>
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<p>Yellow-brown to yellow-green is due to bilirubin (C)</p>
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What is the effect of urinary enzymes N-acetyl-β-D-glucosaminidase (NAG) in detecting renal tubular damage?

<p>Increases in urinary NAG are specific for renal tubular damage (C)</p>
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Which specific enzyme is a membrane-bound enzyme specific for renal tubular damage?

<p>Î¥-glutamyltransferase (GGT) (C)</p>
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