10 Questions
What is the role of small RNAs (sRNAs) in bacterial gene regulation?
Small RNAs can repress levels of one protein and promote another, regulate gene expression, and cause mRNA destruction by RNase, blocking translation.
How does 6S RNA impact gene transcription in growing E. coli cells entering stationary phase?
6S RNA binds RNA Pol, down-regulates transcription, and promotes transcription of survival proteins as cells enter stationary phase.
What is the function of Hfq protein in bacterial mRNA translation regulation?
Hfq aids binding of short, imperfect matching mRNA-sRNA, stabilizes it, and helps sRNA bind mRNA target.
Explain the impact of σ S factor on bacterial gene regulation during stationary phase.
During stationary phase, σ S factor translation is affected by mRNA-sRNA binding, either stimulated or inhibited, and it outcompetes σ 70 subunit to promote transcription of survival proteins.
What are riboswitches and how do they regulate gene expression?
Riboswitches are gene transcripts that can directly sense metabolite concentration changes and control gene expression through changes in secondary structure using RNA sequences.
Which of the following is true about riboswitches?
Riboswitches can bind and respond to simple and complex metabolites
What is the role of σS factor in bacterial gene regulation during stationary phase?
It outcompetes σ70 subunit and promotes transcription of survival proteins
What is the function of Hfq protein in bacterial mRNA translation regulation?
Hfq aids binding of short, imperfect matching mRNA-sRNA and then stabilizes it
How do regulatory RNAs in bacteria primarily impact gene expression?
By binding to complementary target mRNAs to form double-stranded RNAs and causing mRNA destruction
How do sRNAs primarily regulate bacterial mRNA translation?
sRNAs cause mRNA destruction by RNase, blocking translation
Test your knowledge of regulatory RNAs in biology with this quiz. Explore how RNA's single-stranded properties facilitate regulatory roles, how RNAs exploit Watson-Crick base-pairing, and how they alter RNA structure and recruit proteins. Learn about the enzymatic alteration of transcribed RNAs and how RNAs bind proteins and metabolites to alter metabolism. Dive into the world of regulatory RNAs in bacteria and their role in repressing protein levels.
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