12 Questions
Which of the following statements about bacterial sRNAs is true?
Trans-encoded sRNAs can regulate ribosome binding or mRNA degradation.
How do some bacterial sRNAs affect translation?
By disrupting secondary mRNA structure that impedes ribosome binding.
What is the function of the RyhB sRNA in E. coli?
It regulates translation of different targets in response to iron levels.
What happens to the translation of non-essential products in E. coli when iron levels are high?
Their transcripts are translated or stable.
How do bacterial sRNAs affect mRNA degradation?
By recruiting ribonucleases to the target mRNA.
When are trans-encoded sRNAs in bacteria often produced?
In response to specific environmental conditions.
What is the main function of regulatory RNAs?
To control the behavior of other molecules or processes
Which of the following is NOT a principle that holds true for many regulatory RNA molecules?
Regulatory RNAs always interact with proteins to carry out their functions
How can regulatory RNAs act as regulators by base-pairing?
All of the above
How can regulatory RNAs be encoded with respect to their target on the DNA strand?
All of the above
What is the flexibility of RNA structure that allows it to bind to molecules other than RNA/DNA?
RNA can fold into 3D structures
How are bacterial regulatory RNAs typically synthesized?
As independent 100-300 nt transcripts called small RNAs (sRNAs)
Test your knowledge about regulatory RNAs involved in various steps of gene expression. Learn about how RNA molecules play a crucial role in regulating gene expression through base pairing or 3D structures.
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