Regulatory RNAs in Gene Expression Overview Quiz
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Questions and Answers

Which of the following statements about bacterial sRNAs is true?

  • Most base-pairing sRNAs in bacteria are encoded in cis with limited complementarity.
  • Trans-encoded sRNAs can regulate ribosome binding or mRNA degradation. (correct)
  • Bacterial sRNAs only enhance translation by disrupting secondary mRNA structure.
  • All bacterial sRNAs are derived from the 5' UTRs of mRNAs.

    • How do some bacterial sRNAs affect translation?

  • By disrupting secondary mRNA structure that impedes ribosome binding. (correct)
  • By recruiting ribosomes to the mRNA and enhancing translation.
  • By binding to the 3' UTR of the mRNA and promoting ribosome binding.
  • By binding close to the Shine-Dalgarno motif and preventing ribosome binding.

    • What is the function of the RyhB sRNA in E. coli?

  • It recruits ribonucleases to degrade mRNAs encoding non-essential products.
  • It promotes ribosome binding to mRNAs encoding iron-binding proteins.
  • It regulates translation of different targets in response to iron levels. (correct)
  • It binds to the 3' UTRs of mRNAs encoding iron-binding proteins.

    • What happens to the translation of non-essential products in E. coli when iron levels are high?

    <p>Their transcripts are translated or stable.</p> Signup and view all the answers

    How do bacterial sRNAs affect mRNA degradation?

    <p>By recruiting ribonucleases to the target mRNA.</p> Signup and view all the answers

    When are trans-encoded sRNAs in bacteria often produced?

    <p>In response to specific environmental conditions.</p> Signup and view all the answers

    What is the main function of regulatory RNAs?

    <p>To control the behavior of other molecules or processes</p> Signup and view all the answers

    Which of the following is NOT a principle that holds true for many regulatory RNA molecules?

    <p>Regulatory RNAs always interact with proteins to carry out their functions</p> Signup and view all the answers

    How can regulatory RNAs act as regulators by base-pairing?

    <p>All of the above</p> Signup and view all the answers

    How can regulatory RNAs be encoded with respect to their target on the DNA strand?

    <p>All of the above</p> Signup and view all the answers

    What is the flexibility of RNA structure that allows it to bind to molecules other than RNA/DNA?

    <p>RNA can fold into 3D structures</p> Signup and view all the answers

    How are bacterial regulatory RNAs typically synthesized?

    <p>As independent 100-300 nt transcripts called small RNAs (sRNAs)</p> Signup and view all the answers

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