Regulation of Hormones and Carrier Proteins Quiz

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How can some medications affect hormone levels?

By decreasing the destruction of hormones in the liver

By altering the levels of binding proteins or displacing hormones bound to them (correct)

By altering the anatomic relationship of hormone release and action

By increasing the synthesis and secretion of hormones

What is the significance of some binding proteins being able to bind multiple hormones?

It ensures sufficient hormone levels for all binding proteins

It may have clinical implications for endocrine homeostasis (correct)

It increases the specificity of hormone regulation

It decreases the bioavailability of free hormones

How can the anatomic relationship of hormone release and action play a role in their regulation?

It can decrease the destruction of hormones in the liver

It can increase the synthesis and secretion of hormones

It can increase the bioavailability of free hormones

It can markedly curtail the temporal window within which a hormone can act (correct)

What is a critical mechanism that regulates the bioavailability of thyroid hormones?

Regulating the expression and secretion of carrier proteins Signup and view all the answers

What is the role of free hormones in endocrine homeostasis?

Free hormones are needed to feedback and control their rates of synthesis and secretion Signup and view all the answers

Which of the following factors can increase the level of free hormones circulating in the bloodstream?

Decreased binding of hormones to plasma carrier proteins Signup and view all the answers

Which type of hormones are mostly bound to large proteins like sex hormone-binding globulin (SHBG)?

Steroid hormones Signup and view all the answers

What is the main function of plasma carriers in the body?

To modulate levels of the free hormone in target tissues Signup and view all the answers

What is the main role of steroid binding proteins (SBP) in the bloodstream?

To provide a source of free hormone by releasing it from equilibrium Signup and view all the answers

Which type of hormones are soluble in plasma and transported as such?

Catecholamines Signup and view all the answers

Why are only small amounts of free steroid hormones dissolved in the plasma?

Because they are mostly bound to steroid binding proteins Signup and view all the answers

In hormone regulation, what form of the hormone is typically biologically active in target tissues?

Free hormone that can access the extravascular compartment Signup and view all the answers

How do hydrophilic hormones primarily exert their acute effects?

By binding to cell surface receptors Signup and view all the answers

Which class of nuclear receptors allows for a wider dynamic range of gene regulation?

Hormone-binding transcriptional co-activators Signup and view all the answers

Which hormones are key contributors to homeostasis according to the text?

Insulin, cortisol, vasopressin Signup and view all the answers

In hormone regulation, which process occurs with the binding of hydrophobic hormones?

Dislodging of transcriptional co-repressors Signup and view all the answers

How do hydrophilic hormones differ from hydrophobic hormones in terms of receptor type?

Hydrophilic hormones bind to GPCR family receptors Signup and view all the answers

What is the primary mechanism by which hydrophilic hormones exert their acute effects?

Binding to cell surface receptors Signup and view all the answers