Regulation of GFR and RBF
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Questions and Answers

What is the range of systolic arterial pressure at which RBF remains stable?

  • 90 to 180 mmHg (correct)
  • 80 to 150 mmHg
  • 60 to 120 mmHg
  • 100 to 200 mmHg

    • What is the primary function of the autoregulation mechanism in the kidneys?

  • To increase blood pressure
  • To maintain delivery of oxygen and nutrients at a normal level (correct)
  • To decrease RBF
  • To increase GFR

    • What happens to the afferent arterioles when systemic blood pressure increases?

  • They are obliterated
  • They dilate
  • They remain the same
  • They constrict (correct)

    • What is the minimum mean arterial pressure required to perfuse vital organs?

    <p>60 mmHg</p> Signup and view all the answers

    What is the mechanism by which the kidneys respond to changes in systemic blood pressure?

    <p>All of the above</p> Signup and view all the answers

    What is the result of declining systemic blood pressure on the afferent arterioles?

    <p>They dilate</p> Signup and view all the answers

    What is the effect of Angiotensin II on RBF and GFR?

    <p>Decreases RBF and increases GFR</p> Signup and view all the answers

    Which of the following hormones causes vasodilatation and increases RBF?

    <p>Prostaglandin E2</p> Signup and view all the answers

    What is the effect of Natriuretic peptides on RBF and GFR?

    <p>Increases both RBF and GFR</p> Signup and view all the answers

    Which of the following substances is a potent vasoconstrictor of afferent and efferent arterioles?

    <p>Endothelin</p> Signup and view all the answers

    What is the effect of ACE inhibitors on GFR?

    <p>Decreases GFR</p> Signup and view all the answers

    What is the effect of dopamine on RBF and GFR at low doses?

    <p>Increases RBF but has no effect on GFR</p> Signup and view all the answers

    What is the primary function of the juxtaglomerular apparatus in the regulation of GFR?

    <p>To provide feedback signals to both the afferent and the efferent arterioles for efficient autoregulation of GFR</p> Signup and view all the answers

    What happens to the flow rate in the loop of Henle when there is a decrease in GFR?

    <p>It increases, leading to increased reabsorption of sodium and chloride ions</p> Signup and view all the answers

    What is the effect of an increase in arterial blood pressure on GFR?

    <p>It increases GFR by increasing the flow rate in the loop of Henle</p> Signup and view all the answers

    What is the role of the sympathetic nervous system in the regulation of RBF and GFR?

    <p>It causes renal vasoconstriction and decreases RBF and GFR</p> Signup and view all the answers

    What is the purpose of the sympathetic nervous system's control of RBF and GFR during severe acute disturbances?

    <p>To shunt blood to the vital organs such as the heart and brain</p> Signup and view all the answers

    What is the effect of a decrease in sodium chloride delivery to the distal tubule on the afferent arteriole?

    <p>It causes dilation of the afferent arteriole</p> Signup and view all the answers

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