Podcast
Questions and Answers
Which term is used to describe the dynamic steady state of a living cell?
Which term is used to describe the dynamic steady state of a living cell?
- Isotonic state
- Eutrophic state
- Homeorhesis
- Homeostasis (correct)
What happens when the concentration of AMP in a cell is much lower compared to ATP and ADP?
What happens when the concentration of AMP in a cell is much lower compared to ATP and ADP?
- AMP production is favored upon ATP depletion (correct)
- The cell's energetic state is stabilized
- AMP-dependent kinases are inhibited
- ATP production is prioritized over AMP
What role does AMP-dependent kinase (AMPK) play in response to changes in a cell's energetic state?
What role does AMP-dependent kinase (AMPK) play in response to changes in a cell's energetic state?
- Stabilizes ATP levels
- Inhibits protein phosphorylation
- Activates glycogen synthase
- Promotes metabolic fluxes through multiple pathways (correct)
Why are steps 2 and 3 considered near equilibrium in a reaction according to the text?
Why are steps 2 and 3 considered near equilibrium in a reaction according to the text?
What happens when glycogen synthase dissociates from the particle in glycogen metabolism?
What happens when glycogen synthase dissociates from the particle in glycogen metabolism?
How does a change in external circumstances or energy supply impact the homeostasis of a living cell?
How does a change in external circumstances or energy supply impact the homeostasis of a living cell?
What is the relationship between high ATP concentrations and the rate of fructose 1,6-bisphosphate formation in glycolysis?
What is the relationship between high ATP concentrations and the rate of fructose 1,6-bisphosphate formation in glycolysis?
What regulates the activation of Glycogen Synthase by dephosphorylating it?
What regulates the activation of Glycogen Synthase by dephosphorylating it?
Which hormone inhibits the dephosphorylation of Glycogen Synthase by inactivating PP1?
Which hormone inhibits the dephosphorylation of Glycogen Synthase by inactivating PP1?
What causes the association of glycogen phosphorylase with other proteins, including PP1?
What causes the association of glycogen phosphorylase with other proteins, including PP1?
Which signaling pathway turns off GSK by phosphorylating it?
Which signaling pathway turns off GSK by phosphorylating it?
What stimulates the dephosphorylation of Glycogen Synthase during glucose surplus?
What stimulates the dephosphorylation of Glycogen Synthase during glucose surplus?
What is the primary function of isozymes that catalyze the same reaction?
What is the primary function of isozymes that catalyze the same reaction?
How does the sequestration of hexokinase IV by a nuclear binding protein affect enzyme activity?
How does the sequestration of hexokinase IV by a nuclear binding protein affect enzyme activity?
What effect does a high ATP concentration have on PFK activity?
What effect does a high ATP concentration have on PFK activity?
Why is it important to regulate hexokinase IV and not operate it simultaneously with other hexokinases?
Why is it important to regulate hexokinase IV and not operate it simultaneously with other hexokinases?
What is the primary difference between metabolic regulation and metabolic control?
What is the primary difference between metabolic regulation and metabolic control?
What role does isozyme regulation play in metabolic pathways?
What role does isozyme regulation play in metabolic pathways?
