Drugs effecting blood pressure
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Questions and Answers

Which receptor type do cardiac myocytes respond to?

  • D1-receptors
  • α-receptors
  • β1-receptors (correct)
  • β2-receptors

    • What is the main effect of β2-receptor activation?

  • Vasodilation
  • Bronchodilation (correct)
  • Vasoconstriction
  • Cardiac effects

    • What is the main effect of dopamine receptor activation?

  • Bronchodilation
  • Vasoconstriction
  • Cardiac effects
  • Vasodilation (correct)

    • Which enzyme prevents breakdown of cAMP?

    <p>Phosphodiesterase</p> Signup and view all the answers

    Which drug is an inhibitor of phosphodiesterase?

    <p>Milrinone</p> Signup and view all the answers

    What are the cardiac effects of caffeine?

    <p>Tachycardia</p> Signup and view all the answers

    What is the main effect of cardiac glycosides?

    <p>Positive inotropy</p> Signup and view all the answers

    Which factor plays a role in determining blood pressure?

    <p>Renin</p> Signup and view all the answers

    Which class of drugs affects sympathetic function?

    <p>β-blockers</p> Signup and view all the answers

    Which receptor subtype is targeted by α1-blockers?

    <p>α1 receptors</p> Signup and view all the answers

    Which drug is not a first-line treatment for hypertension?

    <p>β-blockers</p> Signup and view all the answers

    Which drug is an option for hypertension in pregnancy?

    <p>Methyldopa</p> Signup and view all the answers

    Which drug class inhibits the action of angiotensin II?

    <p>ACE inhibitors</p> Signup and view all the answers

    Which drug class affects cardiac contractility?

    <p>Glycosides</p> Signup and view all the answers

    Which receptor does Midodrine primarily target?

    <p>α1-adrenoceptor</p> Signup and view all the answers

    What are the indications for using Midodrine?

    <p>Orthostatic hypotension and vasovagal syncope</p> Signup and view all the answers

    Which of the following is NOT an adverse effect of Midodrine?

    <p>Increased urination</p> Signup and view all the answers

    Which class of drugs primarily inhibits renin release from the kidneys?

    <p>β-blockers</p> Signup and view all the answers

    Which of the following drugs primarily affects blood pressure through cardiac contractility?

    <p>Cardiac glycosides</p> Signup and view all the answers

    Which of the following is NOT a major antihypertensive effect of beta-blockers?

    <p>Reduction in sympathetic tone</p> Signup and view all the answers

    Which of the following is a pharmacologic target in the Renin-Angiotensin-Aldosterone System?

    <p>Renin inhibitor</p> Signup and view all the answers

    Which of the following is NOT a side effect of glycosides?

    <p>Headache</p> Signup and view all the answers

    What is the therapeutic index (TI)?

    <p>The ratio of effective dose to toxic dose</p> Signup and view all the answers

    Which of the following conditions is a contraindication for glycoside use?

    <p>Bradycardia</p> Signup and view all the answers

    What is the therapeutic window?

    <p>The range of drug concentrations that produce a therapeutic effect</p> Signup and view all the answers

    What are the symptoms of glycoside intoxication?

    <p>Ventricular tachycardia, delirium, convulsions</p> Signup and view all the answers

    Which of the following is NOT a treatment for glycoside intoxication?

    <p>Forced diuresis</p> Signup and view all the answers

    What is the main adverse effect of glycosides when plasma potassium (K+) is low?

    <p>Arrhythmias</p> Signup and view all the answers

    What is the median effective dose (ED50)?

    <p>The dose at which 50% of patients experience a therapeutic effect</p> Signup and view all the answers

    Which of the following is a caveat of glycoside use?

    <p>Drug interaction with diuretics</p> Signup and view all the answers

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