Drugs effecting blood pressure
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Questions and Answers

Which receptor type do cardiac myocytes respond to?

  • D1-receptors
  • α-receptors
  • β1-receptors (correct)
  • β2-receptors

What is the main effect of β2-receptor activation?

  • Vasodilation
  • Bronchodilation (correct)
  • Vasoconstriction
  • Cardiac effects

What is the main effect of dopamine receptor activation?

  • Bronchodilation
  • Vasoconstriction
  • Cardiac effects
  • Vasodilation (correct)

Which enzyme prevents breakdown of cAMP?

<p>Phosphodiesterase (A)</p> Signup and view all the answers

Which drug is an inhibitor of phosphodiesterase?

<p>Milrinone (B)</p> Signup and view all the answers

What are the cardiac effects of caffeine?

<p>Tachycardia (B)</p> Signup and view all the answers

What is the main effect of cardiac glycosides?

<p>Positive inotropy (A)</p> Signup and view all the answers

Which factor plays a role in determining blood pressure?

<p>Renin (C)</p> Signup and view all the answers

Which class of drugs affects sympathetic function?

<p>β-blockers (A)</p> Signup and view all the answers

Which receptor subtype is targeted by α1-blockers?

<p>α1 receptors (B)</p> Signup and view all the answers

Which drug is not a first-line treatment for hypertension?

<p>β-blockers (C)</p> Signup and view all the answers

Which drug is an option for hypertension in pregnancy?

<p>Methyldopa (C)</p> Signup and view all the answers

Which drug class inhibits the action of angiotensin II?

<p>ACE inhibitors (B)</p> Signup and view all the answers

Which drug class affects cardiac contractility?

<p>Glycosides (B)</p> Signup and view all the answers

Which receptor does Midodrine primarily target?

<p>α1-adrenoceptor (D)</p> Signup and view all the answers

What are the indications for using Midodrine?

<p>Orthostatic hypotension and vasovagal syncope (C)</p> Signup and view all the answers

Which of the following is NOT an adverse effect of Midodrine?

<p>Increased urination (A)</p> Signup and view all the answers

Which class of drugs primarily inhibits renin release from the kidneys?

<p>β-blockers (D)</p> Signup and view all the answers

Which of the following drugs primarily affects blood pressure through cardiac contractility?

<p>Cardiac glycosides (C)</p> Signup and view all the answers

Which of the following is NOT a major antihypertensive effect of beta-blockers?

<p>Reduction in sympathetic tone (D)</p> Signup and view all the answers

Which of the following is a pharmacologic target in the Renin-Angiotensin-Aldosterone System?

<p>Renin inhibitor (B)</p> Signup and view all the answers

Which of the following is NOT a side effect of glycosides?

<p>Headache (A)</p> Signup and view all the answers

What is the therapeutic index (TI)?

<p>The ratio of effective dose to toxic dose (C)</p> Signup and view all the answers

Which of the following conditions is a contraindication for glycoside use?

<p>Bradycardia (B)</p> Signup and view all the answers

What is the therapeutic window?

<p>The range of drug concentrations that produce a therapeutic effect (A)</p> Signup and view all the answers

What are the symptoms of glycoside intoxication?

<p>Ventricular tachycardia, delirium, convulsions (B)</p> Signup and view all the answers

Which of the following is NOT a treatment for glycoside intoxication?

<p>Forced diuresis (B)</p> Signup and view all the answers

What is the main adverse effect of glycosides when plasma potassium (K+) is low?

<p>Arrhythmias (B)</p> Signup and view all the answers

What is the median effective dose (ED50)?

<p>The dose at which 50% of patients experience a therapeutic effect (C)</p> Signup and view all the answers

Which of the following is a caveat of glycoside use?

<p>Drug interaction with diuretics (D)</p> Signup and view all the answers

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