Podcast
Questions and Answers
What is the main cause of clot formation within the blood vessels or the heart?
What is the main cause of clot formation within the blood vessels or the heart?
- Platelet activation and aggregation (correct)
- Production of fibrin
- Formation of Thrombin
- Blood Coagulation
Which type of clot adheres to a vessel wall?
Which type of clot adheres to a vessel wall?
- Thrombin
- Thrombus (correct)
- Embolus
- Fibrin
What is the main function of fibrin in the clot formation process?
What is the main function of fibrin in the clot formation process?
- Activating platelets
- Preventing platelet activation
- Cross-linking and stabilizing the clot (correct)
- Dissolving the clot
Why are both thrombi and emboli considered dangerous?
Why are both thrombi and emboli considered dangerous?
What is the role of platelets in response to vascular trauma?
What is the role of platelets in response to vascular trauma?
What is the first step in the response of platelets to vascular trauma?
What is the first step in the response of platelets to vascular trauma?
What happens during the second step of platelet response to vascular trauma?
What happens during the second step of platelet response to vascular trauma?
What is the final step in the response of platelets to vascular trauma?
What is the final step in the response of platelets to vascular trauma?
What is the role of thrombin in the coagulation cascade?
What is the role of thrombin in the coagulation cascade?
Which factor catalyzes the conversion of fibrinogen to fibrin in clot formation?
Which factor catalyzes the conversion of fibrinogen to fibrin in clot formation?
What is the result of the coagulation cascade in the formation of the clot?
What is the result of the coagulation cascade in the formation of the clot?
What is the primary function of factor Xa in the coagulation cascade?
What is the primary function of factor Xa in the coagulation cascade?
Which of the following is NOT a mechanism by which endothelial cells maintain a nonthrombogenic lining in blood vessels?
Which of the following is NOT a mechanism by which endothelial cells maintain a nonthrombogenic lining in blood vessels?
What is the role of Heparin like proteoglycans in the prevention of thrombosis?
What is the role of Heparin like proteoglycans in the prevention of thrombosis?
Which phenomenon is important in preventing the adhesion of circulating platelets to the blood vessel lining?
Which phenomenon is important in preventing the adhesion of circulating platelets to the blood vessel lining?
What activates the fibrinolytic pathway to prevent thrombosis?
What activates the fibrinolytic pathway to prevent thrombosis?
What is the primary function of platelet aggregation inhibitors?
What is the primary function of platelet aggregation inhibitors?
How do antiplatelet drugs contribute to thrombolytic therapy?
How do antiplatelet drugs contribute to thrombolytic therapy?
What is the role of heparin when administered as an adjunct to antiplatelet therapy?
What is the role of heparin when administered as an adjunct to antiplatelet therapy?
Which signals do platelet aggregation inhibitors interfere with?
Which signals do platelet aggregation inhibitors interfere with?
What is the mechanism of action of aspirin in low doses?
What is the mechanism of action of aspirin in low doses?
What is a therapeutic use of aspirin according to the text?
What is a therapeutic use of aspirin according to the text?
Which adverse effect is associated with aspirin therapy?
Which adverse effect is associated with aspirin therapy?
What is the goal of therapy with aspirin according to the text?
What is the goal of therapy with aspirin according to the text?
What is the most serious side effect associated with the use of ticlopidine?
What is the most serious side effect associated with the use of ticlopidine?
How does clopidogrel exert its effect on platelet activation?
How does clopidogrel exert its effect on platelet activation?
Which hepatic enzyme inhibitor can diminish the action of clopidogrel?
Which hepatic enzyme inhibitor can diminish the action of clopidogrel?
What is the alternative prophylactic therapy to aspirin in the secondary prevention of stroke and myocardial infarction?
What is the alternative prophylactic therapy to aspirin in the secondary prevention of stroke and myocardial infarction?
Which of the following drugs is a murine monoclonal antibody against the GP IIb IIIa?
Which of the following drugs is a murine monoclonal antibody against the GP IIb IIIa?
What is the primary prophylactic use of Dipyridamole in combination with warfarin?
What is the primary prophylactic use of Dipyridamole in combination with warfarin?
Which drug is a coronary vasodilator that increases CAMP and decreases thromboxane A2 synthesis?
Which drug is a coronary vasodilator that increases CAMP and decreases thromboxane A2 synthesis?
What is the main disadvantage associated with the use of Eptifibatide?
What is the main disadvantage associated with the use of Eptifibatide?
What is the primary difference between standard heparin and low molecular weight heparin?
What is the primary difference between standard heparin and low molecular weight heparin?
How does heparin exert its anticoagulant effect?
How does heparin exert its anticoagulant effect?
What is the primary advantage of low molecular weight heparin over standard heparin?
What is the primary advantage of low molecular weight heparin over standard heparin?
Which type of administration is available for low molecular weight heparin?
Which type of administration is available for low molecular weight heparin?
What is the primary therapeutic use of heparin according to the given text?
What is the primary therapeutic use of heparin according to the given text?
Why is intramuscular heparin contraindicated according to the given text?
Why is intramuscular heparin contraindicated according to the given text?
What is the maximal anticoagulant effect of intravenous heparin according to the text?
What is the maximal anticoagulant effect of intravenous heparin according to the text?
In which condition is heparin contraindicated according to the text?
In which condition is heparin contraindicated according to the text?
What is the mechanism of action of warfarin?
What is the mechanism of action of warfarin?
Where does warfarin primarily induce hypocoagulability?
Where does warfarin primarily induce hypocoagulability?
In which condition is warfarin contraindicated?
In which condition is warfarin contraindicated?
What is a therapeutic use of warfarin?
What is a therapeutic use of warfarin?
What is the purpose of thrombolytic therapy?
What is the purpose of thrombolytic therapy?
Which drug is superior to streptokinase and urokinase in dissolving older clots?
Which drug is superior to streptokinase and urokinase in dissolving older clots?
What is the mechanism of action of plasmin in thrombolytic therapy?
What is the mechanism of action of plasmin in thrombolytic therapy?
When is alteplase administered for ischemic stroke?
When is alteplase administered for ischemic stroke?
Which drug is contraindicated in pregnancy, metastatic cancers, and history of cerebrovascular accidents?
Which drug is contraindicated in pregnancy, metastatic cancers, and history of cerebrovascular accidents?
What is the primary therapeutic use of Urokinase according to the given text?
What is the primary therapeutic use of Urokinase according to the given text?
Which drug is a third-generation thrombolytic?
Which drug is a third-generation thrombolytic?
What are the adverse effects associated with Streptokinase?
What are the adverse effects associated with Streptokinase?
Which drug is used to reverse the effect of heparin?
Which drug is used to reverse the effect of heparin?
What is the primary function of Aprotinin?
What is the primary function of Aprotinin?
What is the therapeutic use of Sodium bicarbonate according to the given text?
What is the therapeutic use of Sodium bicarbonate according to the given text?
What is the primary adverse effect associated with the use of Protamine sulfate?
What is the primary adverse effect associated with the use of Protamine sulfate?
